| scholarly article | Q13442814 |
| P356 | DOI | 10.1001/JAMA.2015.2274 |
| P698 | PubMed publication ID | 25771069 |
| P50 | author | Binyan Wang | Q114224208 |
| Genfu Tang | Q114224213 | ||
| Xiuli Shi | Q114224221 | ||
| P2093 | author name string | Jianping Li | |
| Junbo Ge | |||
| Xianhui Qin | |||
| Xiaobin Wang | |||
| Yimin Cui | |||
| Yong Huo | |||
| Xian Wang | |||
| Yan Zhang | |||
| Fan Fan Hou | |||
| Gang Zhao | |||
| Qiang Dong | |||
| Yining Huang | |||
| Dayi Hu | |||
| Xiaoying Li | |||
| Rebecca F Gottesman | |||
| Xinchun Yang | |||
| Dafang Chen | |||
| Yefeng Cai | |||
| Tianlun Yang | |||
| Dingliang Zhu | |||
| Jia Fu | |||
| Xiaoshu Cheng | |||
| Lisheng Liu | |||
| Lianyou Zhao | |||
| Chuanshi Xiao | |||
| Ningling Sun | |||
| Jian'an Wang | |||
| Mingli He | |||
| CSPPT Investigators | |||
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | People's Republic of China | Q148 |
| hypertension | Q95566669 | ||
| folic acid | Q127060 | ||
| prevention | Q1717246 | ||
| P304 | page(s) | 1325-1335 | |
| P577 | publication date | 2015-04-01 | |
| P1433 | published in | The Journal of the American Medical Association | Q1470970 |
| P1476 | title | Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial | |
| P478 | volume | 313 |
| Q64080237 | 2018 Chinese Guidelines for Prevention and Treatment of Hypertension-A report of the Revision Committee of Chinese Guidelines for Prevention and Treatment of Hypertension |
| Q30061994 | A 2015 global update on folic acid-preventable spina bifida and anencephaly |
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| Q51548485 | A novel lateral flow assay based on GoldMag nanoparticles and its clinical applications for genotyping of MTHFR C677T polymorphisms. |
| Q58695665 | Advances in Stroke Prevention |
| Q38795338 | Advances in clinical determinants and neurological manifestations of B vitamin deficiency in adults |
| Q41678728 | Appropriate management of asymptomatic carotid stenosis |
| Q58693582 | Association Between Folic Acid Supplementation and Retinal Atherosclerosis in Chinese Adults With Hypertension Complicated by Diabetes Mellitus |
| Q90435499 | Association Between Maternal Exposure to Lead, Maternal Folate Status, and Intergenerational Risk of Childhood Overweight and Obesity |
| Q39688090 | Association Between Maternal Prepregnancy Body Mass Index and Plasma Folate Concentrations With Child Metabolic Health |
| Q37045214 | Association between Body Mass Index and All-Cause Mortality in Hypertensive Adults: Results from the China Stroke Primary Prevention Trial (CSPPT) |
| Q64104483 | Association between CYP3A4 gene rs4646437 polymorphism and the risk of hypertension in Chinese population: a case-control study |
| Q54937833 | Association between homocysteine and conventional predisposing factors on risk of stroke in patients with hypertension. |
| Q91655123 | Association between homocysteine level and blood pressure traits among Tibetans: A cross-sectional study in China |
| Q40448791 | Association between hyperhomocysteinemia and stroke with atherosclerosis and small artery occlusion depends on homocysteine metabolism-related vitamin levels in Chinese patients with normal renal function. |
| Q91496995 | Association between serum folate and cardiovascular deaths among adults with hypertension |
| Q49393259 | Association of Homocysteine with Aysmptomatic Intracranial and Extracranial Arterial Stenosis in Hypertension Patients |
| Q36597633 | Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype. |
| Q37374037 | Association of MTHFR, SLC19A1 Genetic Polymorphism, Serum Folate, Vitamin B12 and Hcy Status with Cognitive Functions in Chinese Adults |
| Q38879703 | Association of Maternal Plasma Folate and Cardiometabolic Risk Factors in Pregnancy with Elevated Blood Pressure of Offspring in Childhood. |
| Q92025223 | Association of brachial-ankle pulse wave velocity and carotid plaque in Chinese hypertensive adults: effect modification by age |
| Q92228663 | Association of plasma retinol levels with incident cancer risk in Chinese hypertensive adults: a nested case-control study |
| Q97550099 | Association of self-reported sleep duration and quality with BaPWV levels in hypertensive patients |
| Q40250990 | Association of serum uric acid with increased risk of cancer among hypertensive Chinese |
| Q55438718 | Association of total homocysteine with blood pressure in a general population of Chinese adults: a cross-sectional study in Jiangsu province, China. |
| Q92502407 | Associations between Blood Pressure Indices and Brachial-ankle Pulse Wave Velocity in Treated Hypertensive Adults: results from the China Stroke Primary Prevention Trial (CSPPT) |
| Q58701203 | Asymptomatic Carotid Stenosis: Intervention or Best Medical Therapy? |
| Q51563533 | Atherosclerosis determinants in renal disease: how much is homocysteine involved? |
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| Q47216784 | Biochemical and Clinical Impact of Organic Uremic Retention Solutes: A Comprehensive Update |
| Q90003321 | Biomarkers of Nutrition for Development (BOND): Vitamin B-12 Review |
| Q38769349 | Body mass index is inversely associated with arterial stiffness in Chinese adults with primary hypertension: results from the China Stroke Primary Prevention Trial (CSPPT). |
| Q28070413 | Causes, Consequences and Public Health Implications of Low B-Vitamin Status in Ageing |
| Q38879090 | Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's disease |
| Q36846237 | Characteristics of U.S. Adults with Usual Daily Folic Acid Intake above the Tolerable Upper Intake Level: National Health and Nutrition Examination Survey, 2003-2010. |
| Q38379497 | China Stroke Primary Prevention Trial: Visit-to-Visit Systolic Blood Pressure Variability Is an Independent Predictor of Primary Stroke in Hypertensive Patients |
| Q37670918 | China cardiovascular diseases report 2015: a summary |
| Q36436750 | Choline metabolites: gene by diet interactions |
| Q46124630 | Chronic Kidney Disease Induces Inflammatory CD40+ Monocyte Differentiation via Homocysteine Elevation and DNA Hypomethylation |
| Q50000826 | Chronic kidney disease and stroke: more observations but no trials |
| Q90724220 | Circulating Folate Concentrations and Risk of Peripheral Neuropathy and Mortality: A Retrospective Cohort Study in the U.K. |
| Q55122326 | Clinical utility of serum folate measurement in tertiary care patients: Argument for revising reference range for serum folate from 3.0 ng/mL to 13.0 ng/mL. |
| Q50048647 | Comparison of oxidative stress biomarkers in hypertensive patients with or without hyperhomocysteinemia |
| Q92535278 | Current state of cardiovascular research in China |
| Q36348620 | Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia |
| Q55476982 | Deleting Death and Dialysis: Conservative Care of Cardio-Vascular Risk and Kidney Function Loss in Chronic Kidney Disease (CKD). |
| Q30238971 | Dietary Supplements and Risk of Cause-Specific Death, Cardiovascular Disease, and Cancer: A Systematic Review and Meta-Analysis of Primary Prevention Trials |
| Q30251418 | Dietary supplements and disease prevention - a global overview. |
| Q96121418 | Distribution characteristics of circulating homocysteine and folate and related factors in agriculture, stock-raising and urban populations: a cross-sectional survey |
| Q38568617 | Does personalized medicine exist and can you test it in a clinical trial? |
| Q46344721 | Effect of B-vitamins on stroke risk among individuals with vascular disease who are not on antiplatelets: A meta-analysis |
| Q89970118 | Effect of Banxia Baizhu Tianma Tang for H-type hypertension: A protocol for a systematic review |
| Q38378430 | Effect of Baseline Nutritional Status on Long-term Multivitamin Use and Cardiovascular Disease Risk: A Secondary Analysis of the Physicians' Health Study II Randomized Clinical Trial |
| Q36507492 | Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine. |
| Q92339758 | Effect of Intensive Blood Pressure Control on Carotid Morphology and Hemodynamics in Chinese Patients with Hyperhomocysteinemia-Type Hypertension and High Risk of Stroke |
| Q39908471 | Effect of folic acid supplementation on cancer risk among adults with hypertension in China: A randomized clinical trial |
| Q40444444 | Effect of folic acid supplementation on risk of new-onset diabetes in adults with hypertension in China: Findings from the China Stroke Primary Prevention Trial (CSPPT). |
| Q58545775 | Effect of long-term low-dose folic acid supplementation on degree of total homocysteine-lowering: major effect modifiers |
| Q36926923 | Effect of renal impairment on atherosclerosis: only partially mediated by homocysteine |
| Q30248614 | Effect of vitamin B supplementation on cancer incidence, death due to cancer, and total mortality: A PRISMA-compliant cumulative meta-analysis of randomized controlled trials |
| Q90989803 | Electrocardiographic-left ventricular hypertrophy and incident stroke among Chinese hypertensive adults |
| Q47422208 | Elevated Plasma Homocysteine Level Increased the Risk of Early Renal Impairment in Acute Ischemic Stroke Patients |
| Q24186134 | Folate supplementation in people with sickle cell disease |
| Q54254875 | Folate supplementation in people with sickle cell disease. |
| Q52654777 | Folic Acid Exerts Post-Ischemic Neuroprotection In Vitro Through HIF-1α Stabilization. |
| Q42699149 | Folic Acid Impairs the Uptake of 5-Methyltetrahydrofolate in Human Umbilical Vascular Endothelial Cells |
| Q41866231 | Folic Acid Promotes Recycling of Tetrahydrobiopterin and Protects Against Hypoxia-Induced Pulmonary Hypertension by Recoupling Endothelial Nitric Oxide Synthase |
| Q34537420 | Folic Acid Supplementation and the Risk of Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials |
| Q50102454 | Folic Acid and Homocysteine in Chronic Kidney Disease and Cardiovascular Disease Progression: Which Comes First? |
| Q64259980 | Folic Acid and Vitamin B12 Administration in CKD, Why Not? |
| Q36580892 | Folic Acid and Vitamins D and B12 Correlate With Homocysteine in Chinese Patients With Type-2 Diabetes Mellitus, Hypertension, or Cardiovascular Disease |
| Q54964325 | Folic Acid in Stroke Prevention in Countries without Mandatory Folic Acid Food Fortification: A Meta-Analysis of Randomized Controlled Trials. |
| Q52640082 | Folic acid delays development of atherosclerosis in low-density lipoprotein receptor-deficient mice. |
| Q42068247 | Folic acid inhibits dedifferentiation of PDGF-BB-induced vascular smooth muscle cells by suppressing mTOR/P70S6K signaling |
| Q46265232 | Folic acid prevents cardiac dysfunction and reduces myocardial fibrosis in a mouse model of high-fat diet-induced obesity |
| Q90151571 | Global case studies for chronic kidney disease/end-stage kidney disease care |
| Q41430020 | H-Type hypertension, stroke and diabetes in China: Opportunities for primary prevention |
| Q30238784 | Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association |
| Q37373971 | High Prevalence of Hyperhomocysteinemia and Its Association with Target Organ Damage in Chinese Patients with Chronic Kidney Disease |
| Q47143985 | Higher Adiposity Is Associated With Slower Cognitive Decline in Hypertensive Patients: Secondary Analysis of the China Stroke Primary Prevention Trial |
| Q50095328 | Highlights from ACC 15 Scientific Sessions: Part 2. |
| Q94595283 | Highlights of the 2018 Chinese hypertension guidelines |
| Q89156950 | Homocysteine Levels and Arterial Stiffness in the General Population |
| Q36012440 | Homocysteine Metabolism Gene Polymorphisms (MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G) Jointly Elevate the Risk of Folate Deficiency |
| Q92588783 | Homocysteine and IgA nephropathy: observational and Mendelian randomization analyses |
| Q40323990 | Homocysteine and all-cause mortality in hypertensive adults without pre-existing cardiovascular conditions: Effect modification by MTHFR C677T polymorphism |
| Q91742250 | Homocysteine and small vessel stroke: A mendelian randomization analysis |
| Q91728518 | Homocysteine is not a risk factor for subclinical coronary atherosclerosis in asymptomatic individuals |
| Q100945970 | Homocysteine level is positively and independently associated with serum creatinine and urea nitrogen levels in old male patients with hypertension |
| Q52985410 | Homocysteine lowering for stroke prevention: Unravelling the complexity of the evidence. |
| Q38537945 | Homocysteine, methylenetetrahydrofolate reductase, folate status and atherothrombosis: A mechanistic and clinical perspective |
| Q38620630 | Homocysteine-lowering interventions for preventing cardiovascular events. |
| Q52795383 | Homocysteine-reducing B vitamins and ischemic heart disease: a separate-sample Mendelian randomization analysis. |
| Q64994317 | Hyperhomocysteinaemia is an independent risk factor for peripheral arterial disease in a Chinese Han population. |
| Q36569806 | Hyperhomocysteinaemia is an independent risk factor of abdominal aortic aneurysm in a Chinese Han population. |
| Q38896912 | Hyperhomocysteinemia impairs regional blood flow: involvements of endothelial and neuronal nitric oxide. |
| Q37045221 | Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats |
| Q36265878 | Hyperhomocysteinemia predicts renal function decline: a prospective study in hypertensive adults |
| Q26745496 | Hypertension and Related Cardiovascular Disease Burden in China |
| Q87022031 | Hypertension. Folic acid reduces stroke risk |
| Q52313611 | Identification of homocysteine-suppressive mitochondrial ETC complex genes and tissue expression profile - Novel hypothesis establishment. |
| Q89260249 | Identifying the optimal blood pressure target for ideal health |
| Q41104017 | Impact of Achieved Blood Pressure on First Stroke in Uncomplicated Grade 1 Hypertension |
| Q50074639 | Impact of achieved blood pressure on renal function decline and first stroke in hypertensive patients with chronic kidney disease |
| Q41429816 | Impact of dietary supplementation of one-carbon metabolism on neural recovery |
| Q92298815 | Improving diabetic and hypertensive retinopathy with a medical food containing L-methylfolate: a preliminary report |
| Q49387312 | Independent and combined effect of bilirubin and smoking on the progression of chronic kidney disease |
| Q47183307 | Individualized prevention against hypertension based on Traditional Chinese Medicine Constitution Theory: A large community-based retrospective, STROBE-compliant study among Chinese population |
| Q37631826 | Influence of food groups on plasma total homocysteine for specific MTHFR C677T genotypes in Chinese population |
| Q47142117 | Influence of renal function on the association between homocysteine level and risk of ischemic stroke |
| Q90340474 | Interpreting stimulated plasma renin and aldosterone to select physiologically individualized therapy for resistant hypertension: importance of the class of stimulating drugs |
| Q36023213 | Joint associations of folate, homocysteine and MTHFR, MTR and MTRR gene polymorphisms with dyslipidemia in a Chinese hypertensive population: a cross-sectional study |
| Q38807977 | Joint effect of maternal plasma homocysteine and prepregnancy obesity on child blood pressure: a prospective birth cohort study |
| Q92933640 | Lack of association between serum homocysteine level and middle cerebral artery stenosis |
| Q41203894 | Lipid levels and new-onset diabetes in a hypertensive population: the China Stroke Primary Prevention Trial |
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| Q95322549 | Low doses of folic acid can reduce hyperhomocysteinemia-induced glomerular injury in spontaneously hypertensive rats |
| Q54087842 | Low risk of ischaemic stroke in hyperhomocysteinaemia. |
| Q47102116 | MTHFR C677T gene polymorphism and the severity of coronary lesions in acute coronary syndrome |
| Q92825909 | MTHFR Gene Mutations Correlate with White Matter Disease Burden and Predict Cerebrovascular Disease and Dementia |
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| Q39129432 | Medical cost savings in Sakado City and worldwide achieved by preventing disease by folic acid fortification. |
| Q89751370 | Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia |
| Q51148410 | Methylene Tetrahydrofolate Reductase (MTHFR) rs868014 Polymorphism Regulated by miR-1203 Associates with Risk and Short Term Outcome of Ischemic Stroke. |
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| Q37737269 | Nonspecific ST-T changes associated with unsatisfactory blood pressure control among adults with hypertension in China: Evidence from the CSPTT study |
| Q64083804 | Nutrition and Risk of Stroke |
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| Q50244607 | Plasma Homocysteine Levels Are Associated With Circadian Blood Pressure Variation in Chinese Hypertensive Adults |
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| Q47159796 | Plasma proteomics reveals coagulation, inflammation, and metabolic shifts in H-type hypertension patients with and without acute ischemic stroke |
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