A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus

scientific article published on 18 May 2016

A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus is …
instance of (P31):
meta-analysisQ815382
scholarly articleQ13442814

External links are
P356DOI10.1136/ANNRHEUMDIS-2016-209436
P698PubMed publication ID27193031

P50authorMarta E Alarcón-RiquelmeQ28751753
Francisco J. García-HernandezQ58467781
Isidoro González-ÁlvaroQ88287923
José Mario SabioQ90562828
Miguel Angel Gonzalez-GayQ91377370
M Francisca González-EscribanoQ114417520
Carles TolosaQ114417521
Jane WorthingtonQ29998784
Leonid PadyukovQ42291137
Patricia E CarreiraQ51556977
Norberto Ortego-CentenoQ54165708
Javier MartinQ55089349
Alejandro BalsaQ57028851
Timothy VyseQ58232638
P2093author name stringAna Suárez
Antonio González
Ana Márquez
Luis Rodríguez-Rodríguez
Laura Vidal-Bralo
María M Ayala-Gutiérrez
P2860cites workA flexible and accurate genotype imputation method for the next generation of genome-wide association studiesQ21129496
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease lociQ21145042
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other lociQ24306903
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lociQ28281906
Genetics and epigenetics of rheumatoid arthritisQ28534348
Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility lociQ28924378
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared lociQ28943258
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac diseaseQ28943307
Genetics of rheumatoid arthritis contributes to biology and drug discoveryQ29417000
Annotation of functional variation in personal genomes using RegulomeDBQ29614867
STRING v10: protein-protein interaction networks, integrated over the tree of lifeQ29615545
Gene Ontology Consortium: going forwardQ29616846
Replication of recently identified systemic lupus erythematosus genetic associations: a case-control studyQ30488972
A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlapQ34102802
Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosusQ34551268
How do autoimmune diseases cluster in families? A systematic review and meta-analysisQ34622288
Role of the conserved oligomeric Golgi (COG) complex in protein glycosylationQ34763238
Shared signatures between rheumatoid arthritis, systemic lupus erythematosus and Sjögren's syndrome uncovered through gene expression meta-analysis.Q34968138
Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients.Q35953527
Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihoodQ36294045
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.Q36343939
Deficiency of Subunit 6 of the Conserved Oligomeric Golgi Complex (COG6-CDG): Second Patient, Different PhenotypeQ36433417
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility lociQ37153818
Genetic susceptibility to SLE: recent progress from GWAS.Q38080314
Allele-specific transcription factor binding to common and rare variants associated with disease and gene expressionQ39906487
Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritisQ41779186
Rheumatoid arthritis does not share most of the newly identified systemic lupus erythematosus genetic factors.Q42632049
Association of AFF1 rs340630 and AFF3 rs10865035 polymorphisms with systemic lupus erythematosus in a Chinese populationQ46902670
Systemic lupus erythematosus.Q53202066
Evidence of association of macrophage migration inhibitory factor gene polymorphisms with systemic lupus erythematosusQ56452938
Rheumatoid arthritisQ56656479
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectsystemic lupus erythematosusQ1485
rheumatoid arthritisQ187255
P304page(s)286-294
P577publication date2016-05-18
P1433published inAnnals of the Rheumatic DiseasesQ4767876
P1476titleA combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus
P478volume76

Reverse relations

cites work (P2860)
Q64075676'RA and the microbiome: do host genetic factors provide the link?
Q89556548A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn's disease
Q37691169Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.
Q55092221Association of a rare variant of the TNFSF13B gene with susceptibility to Rheumatoid Arthritis and Systemic Lupus Erythematosus.
Q98222385Clinical value of DNA methylation markers in autoimmune rheumatic diseases
Q49644349Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis.
Q64100517Exploring Impact of Rare Variation in Systemic Lupus Erythematosus by a Genome Wide Imputation Approach
Q92725660Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct
Q64106861Genetic variants differentially associated with rheumatoid arthritis and systemic lupus erythematosus reveal the disease-specific biology
Q50526496Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci.
Q90681080Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases
Q92026216High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation
Q64079480Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients
Q48502389Moving towards a molecular taxonomy of autoimmune rheumatic diseases
Q48219517NLRP1, PTPN22 and PADI4 gene polymorphisms and rheumatoid arthritis in ACPA-positive Singaporean Chinese
Q33631616Omics Approaches to Identify Potential Biomarkers of Inflammatory Diseases in the Focal Adhesion Complex
Q92662245The Potential Role of Genomic Medicine in the Therapeutic Management of Rheumatoid Arthritis
Q36127459Urine metabolome profiling of immune-mediated inflammatory diseases
Q52365346Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.

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