Checkpoints that control B cell development

scientific article published on 04 May 2015

Checkpoints that control B cell development is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI78083
P932PMC publication ID4497745
P698PubMed publication ID25938781

P2093author name stringFritz Melchers
P2860cites workGalectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggeringQ24538653
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Positive and negative selection of natural autoreactive B cellsQ84823635
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A lineage of myeloid cells independent of Myb and hematopoietic stem cellsQ29620147
Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesisQ33194891
Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.Q33381545
S1P1 receptor directs the release of immature B cells from bone marrow into blood.Q33839902
Revising B cell receptorsQ33935117
Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cellsQ33996199
Fidelity and infidelity in commitment to B-lymphocyte lineage developmentQ33996246
Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cellsQ34125345
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.Q34134909
Regulation of the HIF-1alpha level is essential for hematopoietic stem cellsQ34134916
Selection events operating at various stages in B cell developmentQ34167959
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B cell development pathwaysQ34178187
Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunitsQ34230576
Hematopoiesis is severely altered in mice with an induced osteoblast deficiencyQ34290169
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Ontogeny of the hematopoietic systemQ34653344
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Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain componentsQ36399113
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ITAM-mediated tonic signalling through pre-BCR and BCR complexesQ36430140
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Rules for the rearrangement events at the L chain gene loci of the mouseQ36751802
B-cell self-tolerance in humansQ36942517
Sites and stages of autoreactive B cell activation and regulation.Q37058621
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Organization of immunological memory by bone marrow stromaQ37692177
Self-recognition and clonal selection: autoreactivity drives the generation of B cellsQ37991451
Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunityQ38166250
Generation of memory B cells inside and outside germinal centersQ38194532
The imperfect control of self-reactive germinal center B cellsQ38200841
Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.Q39246618
The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.Q39705131
Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions.Q39866994
Genes required for B cell developmentQ40271553
In-vitro analyses of mechanisms of B-cell developmentQ40424900
Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organsQ40590092
Cutting edge: signaling and cell surface expression of a mu H chain in the absence of lambda 5: a paradigm revisited.Q40633243
Deficiency of the adaptor SLP-65 in pre-B-cell acute lymphoblastic leukaemiaQ40645791
Immature multipotent hemopoietic progenitors lacking long-term bone marrow-reconstituting activity in the aorta-gonad-mesonephros region of murine day 10 fetusesQ40826652
Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangementQ41278530
Immature surface Ig+ B cells can continue to rearrange kappa and lambda L chain gene lociQ41522821
Germinal center reaction: antigen affinity and presentation explain it all.Q41835569
The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesisQ41998237
Interaction of murine precursor B cell receptor with stroma cells is controlled by the unique tail of lambda 5 and stroma cell-associated heparan sulfate.Q42046827
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.Q42064178
Residues that mediate DNA binding of autoimmune antibodiesQ42799912
The nonimmunoglobulin portion of lambda5 mediates cell-autonomous pre-B cell receptor signalingQ43483568
Editors and editing of anti-DNA receptors.Q43832072
Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cellsQ45856689
Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.Q46048350
Autoreactivity and allelic inclusion in a B cell nuclear transfer mouseQ46761763
Mutations affecting either generation or survival of cells influence the pool size of mature B cellsQ47263297
Cellular niches controlling B lymphocyte behavior within bone marrow during development.Q47365661
Multiple organ-reactive monoclonal autoantibodiesQ48777324
Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.Q50749492
Thymic stromal lymphopoietin induces early human B-cell proliferation and differentiation.Q51916152
The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.Q52112319
B-cell progenitors and precursors change their microenvironment in fetal liver during early development.Q52884003
The non-Ig parts of the VpreB and λ5 proteins of the surrogate light chain play opposite roles in the surface representation of the precursor B cell receptor.Q52888393
Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms.Q54310645
A critical role of λ5 protein in B cell developmentQ57339983
The Biology of Hematopoietic Stem CellsQ58043095
Intraembryonic, but Not Yolk Sac Hematopoietic Precursors, Isolated before Circulation, Provide Long-Term Multilineage ReconstitutionQ58478756
SnapShot: The Germinal Center ReactionQ58859205
Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.Q64890383
Definitive hematopoiesis is autonomously initiated by the AGM regionQ71535827
Does immunological tolerance explain the waste in the B-lymphocyte immune system? Experiment and theoryQ71556149
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2203-2210
P577publication date2015-05-04
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleCheckpoints that control B cell development
P478volume125

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cites work (P2860)
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