miR-124, -128, and -137 Orchestrate Neural Differentiation by Acting on Overlapping Gene Sets Containing a Highly Connected Transcription Factor Network.

scientific article published on 07 September 2015

miR-124, -128, and -137 Orchestrate Neural Differentiation by Acting on Overlapping Gene Sets Containing a Highly Connected Transcription Factor Network. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/STEM.2204
P698PubMed publication ID26369286
P5875ResearchGate publication ID281608386

P50authorLuiz O. F. PenalvaQ73585023
Bruna Renata Silva CorrêaQ82760577
P2093author name stringAllison N Tegge
Erzsebet Kokovay
Mei Qiao
Swetha Mahesula
Márcia C T Santos
Marco A R Ferreira
Luana Q Kohnke
P2860cites workA miRNA signature of prion induced neurodegenerationQ21092168
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cellsQ21245271
Human MicroRNA targetsQ21563637
Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2FQ24317554
Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signalingQ24322974
MicroRNAs: regulators of neuronal fateQ24596859
The interplay between transcription factors and microRNAs in genome-scale regulatory networksQ24610233
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiationQ24627354
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicingQ24631683
Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and CufflinksQ24633890
Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interactionQ24650233
TopHat: discovering splice junctions with RNA-SeqQ24655505
The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS developmentQ24674190
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
microRNAs: key triggers of neuronal cell fateQ26865206
MicroRNAs and neuronal developmentQ27026231
Prediction of mammalian microRNA targetsQ27860498
An expansive human regulatory lexicon encoded in transcription factor footprintsQ28274429
miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitroQ28276065
Confirmed rare copy number variants implicate novel genes in schizophreniaQ28276679
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domainQ28295806
Potential Impact of miR-137 and Its Targets in SchizophreniaQ30454963
Transcription factor SP4 is a susceptibility gene for bipolar disorderQ30490052
Sp1 expression regulates lung tumor progression.Q30524654
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's diseaseQ33292417
MicroRNA networks in mouse lung organogenesisQ33592965
Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-betaQ33605734
Cross talk between microRNA and epigenetic regulation in adult neurogenesisQ33788417
Reprogramming of miRNA networks in cancer and leukemiaQ33812540
Computational prediction of microRNA networks incorporating environmental toxicity and disease etiologyQ33846279
MicroRNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expressionQ33947119
miR-34a regulates mouse neural stem cell differentiationQ33998797
TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neuronsQ34011533
Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death geneQ34017894
Is adult neurogenesis essential for olfaction?Q34146079
Altered microRNA regulation in Huntington's disease modelsQ34146968
Disc1 variation leads to specific alterations in adult neurogenesisQ34278135
Adult neural stem cells stake their groundQ34372142
Regulation of miRNA expression during neural cell specificationQ34412991
Origin of oligodendrocytes in the subventricular zone of the adult brain.Q34551388
Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia.Q34642142
Chromatin remodelling during developmentQ34698385
MiR-124 regulates early neurogenesis in the optic vesicle and forebrain, targeting NeuroD1.Q34779491
Allele variants in functional MicroRNA target sites of the neurotrophin-3 receptor gene (NTRK3) as susceptibility factors for anxiety disordersQ34976084
Rapid neurogenesis through transcriptional activation in human stem cells.Q34987004
Transcriptional factor specificity protein 1 (SP1) promotes the proliferation of glioma cells by up-regulating midkine (MDK).Q35027553
Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decayQ35067929
Understanding cooperativity of microRNAs via microRNA association networksQ35098185
An axis involving SNAI1, microRNA-128 and SP1 modulates glioma progressionQ35193962
miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cellsQ35818683
MicroRNAs in Neural Stem Cells and NeurogenesisQ35819878
Posttranscriptional control of neuronal development by microRNA networksQ36534223
Specific microRNAs modulate embryonic stem cell-derived neurogenesis.Q37020782
An Sp1 transcription factor coordinates caspase-dependent and -independent apoptotic pathwaysQ37107003
Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytesQ37107284
The role of microRNAs in the regulation of cancer stem cellsQ37428403
Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cellsQ37505070
Expression of microRNAs and other small RNAs in prefrontal cortex in schizophrenia, bipolar disorder and depressed subjectsQ37520746
MicroRNAs in brain development and function: a matter of flexibility and stability.Q37564200
miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactionsQ37661923
Genome-wide survey of tissue-specific microRNA and transcription factor regulatory networks in 12 tissuesQ37738471
MicroRNA regulation of neural stem cells and neurogenesisQ37808577
MicroRNAs in brain development and degenerationQ37885268
Functions of noncoding RNAs in neural development and neurological diseasesQ37942074
Dynamic Roles of microRNAs in NeurogenesisQ38015819
Chromatin-based epigenetics of adult subventricular zone neural stem cellsQ38151696
MicroRNA-dependent genetic networks during neural developmentQ38215233
cAMP response element-binding protein regulates differentiation and survival of newborn neurons in the olfactory bulb.Q38319189
Sp1 is upregulated in human glioma, promotes MMP-2-mediated cell invasion and predicts poor clinical outcomeQ38411011
Gene dysregulation in Huntington's disease: REST, microRNAs and beyondQ38510103
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factorsQ39283917
Sp1 is required for transforming growth factor-beta-induced mesenchymal transition and migration in pancreatic cancer cellsQ40169686
MicroRNA-128 governs neuronal excitability and motor behavior in miceQ41833350
miR-124 regulates adult neurogenesis in the subventricular zone stem cell nicheQ42243673
Sp1-dependent regulation of PPARα in bone metabolismQ42452888
A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity.Q42751771
Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expressionQ42822474
Increased SP4 and SP1 transcription factor expression in the postmortem hippocampus of chronic schizophreniaQ44180870
Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cellsQ44440498
Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activityQ44802879
Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's diseaseQ45290680
JWA suppresses tumor angiogenesis via Sp1-activated matrix metalloproteinase-2 and its prognostic significance in human gastric cancerQ45354167
The subventricular zone continues to generate corpus callosum and rostral migratory stream astroglia in normal adult miceQ46108638
Smad2 and Smad3 cooperate and antagonize simultaneously in vertebrate neurogenesisQ46109511
Impaired postnatal development of hippocampal dentate gyrus in Sp4 null mutant miceQ46150035
Drosophila miR-124 regulates neuroblast proliferation through its target anachronismQ47221762
TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitorsQ48143025
MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins.Q48690916
Simple designs and model-free tests for synergy.Q52371777
MicroRNA-124 regulates neuronal differentiation of mesenchymal stem cells by targeting Sp1 mRNA.Q52978378
P433issue1
P304page(s)220-232
P577publication date2015-09-15
P1433published inStem CellsQ15724411
P1476titlemiR-124, -128, and -137 Orchestrate Neural Differentiation by Acting on Overlapping Gene Sets Containing a Highly Connected Transcription Factor Network
P478volume34

Reverse relations

cites work (P2860)
Q50015658A comprehensive review of the genetic and biological evidence supports a role for MicroRNA-137 in the etiology of schizophrenia.
Q55314026A direct regulatory link between microRNA-137 and SHANK2: implications for neuropsychiatric disorders.
Q42317072Age-related epigenetic regulation in the brain and its role in neuronal diseases
Q90024483Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development
Q42730528Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes.
Q53082855BRM270 inhibits cancer stem cell maintenance via microRNA regulation in chemoresistant A549 lung adenocarcinoma cells.
Q38910482Candidate microRNAs as biomarkers of thyroid carcinoma: a systematic review, meta-analysis, and experimental validation
Q64228930Co-administration of Anti microRNA-124 and -137 Oligonucleotides Prevents Hippocampal Neural Stem Cell Loss Upon Non-convulsive Seizures
Q39290532Combination of RNA Interference and Stem Cells for Treatment of Central Nervous System Diseases
Q33633968Exosome Mediated Delivery of miR-124 Promotes Neurogenesis after Ischemia
Q64076951Exosome-transmitted miR-128-3p increase chemosensitivity of oxaliplatin-resistant colorectal cancer
Q26772836Exosomes as Novel Regulators of Adult Neurogenic Niches
Q61454780Heterogeneous Expression of SDF1 Retains Actively Proliferating Neural Progenitors in the Capillary Compartment of the Niche
Q41945586Lentivirus-mediated microRNA-124 gene-modified bone marrow mesenchymal stem cell transplantation promotes the repair of spinal cord injury in rats
Q37670480MSCs-Derived Exosomes and Neuroinflammation, Neurogenesis and Therapy of Traumatic Brain Injury
Q35888866MiR-124 Promote Neurogenic Transdifferentiation of Adipose Derived Mesenchymal Stromal Cells Partly through RhoA/ROCK1, but Not ROCK2 Signaling Pathway
Q37589647MiR-124 inhibits the migration and invasion of human hepatocellular carcinoma cells by suppressing integrin αV expression
Q92964646MicroRNA changes of bone marrow-derived mesenchymal stem cells differentiated into neuronal-like cells by Schwann cell-conditioned medium
Q58751612MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12
Q60959991MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus
Q42291765Synergic Functions of miRNAs Determine Neuronal Fate of Adult Neural Stem Cells.
Q61118457The functional synergism of microRNA clustering provides therapeutically relevant epigenetic interference in glioblastoma
Q90402261miR-124 participates in the proliferation and differentiation of brain glioma stem cells through regulating Nogo/NgR expression
Q64108189miR‑329‑3p regulates neural stem cell proliferation by targeting E2F1

Search more.