The naturally occurring flavolignan, deoxypodophyllotoxin, inhibits lipopolysaccharide-induced iNOS expression through the NF-kappaB activation in RAW264.7 macrophage cells

scientific article published on July 2008

The naturally occurring flavolignan, deoxypodophyllotoxin, inhibits lipopolysaccharide-induced iNOS expression through the NF-kappaB activation in RAW264.7 macrophage cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1248/BPB.31.1312
P953full work available at URLhttps://www.jstage.jst.go.jp/article/bpb/31/7/31_7_1312/_pdf
P698PubMed publication ID18591766

P7228access restriction statusopen accessQ232932
P2093author name stringSeung Ho Lee
Meihua Jin
Cheorl-Ho Kim
Tae Cheon Jeong
Eunkyung Lee
Hyeun Wook Chang
Yun Kyung Kim
Tae Chul Moon
Ju Hae Yang
Seok-Jong Suh
Zhejiu Quan
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Disialoganglioside (GD3) synthase gene expression suppresses vascular smooth muscle cell responses via the inhibition of ERK1/2 phosphorylation, cell cycle progression, and matrix metalloproteinase-9 expressionQ34324319
Molecular basis of chemoprevention by resveratrol: NF-kappaB and AP-1 as potential targetsQ35914344
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharideQ38318972
Deoxypodophyllotoxin (DPT) inhibits eosinophil recruitment into the airway and Th2 cytokine expression in an OVA-induced lung inflammationQ38510058
Dual inhibition of cyclooxygenases-2 and 5-lipoxygenase by deoxypodophyllotoxin in mouse bone marrow-derived mast cellsQ38517264
Deoxypodophyllotoxin, a naturally occurring lignan, inhibits the passive cutaneous anaphylaxis reactionQ38517523
ERK1/2 mediates TNF-alpha-induced matrix metalloproteinase-9 expression in human vascular smooth muscle cells via the regulation of NF-kappaB and AP-1: Involvement of the ras dependent pathwayQ38518281
Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesisQ40386904
Cell biology. NO says yes to mitochondriaQ40671843
Nuclear factor kappa B, a mediator of lipopolysaccharide effectsQ40825105
Inhibitory effects of podophyllotoxin derivatives on herpes simplex virus replicationQ40983859
Antiproliferative constituents in umbelliferae plants. III. Constituents in the root and the ground part of Anthriscus sylvestris HoffmQ41035500
Biosynthesis and action of nitric oxide in mammalian cellsQ41684081
Deoxypodophyllotoxin; the cytotoxic and antiangiogenic component from Pulsatilla koreanaQ43933854
Flow cytometric estimation on cytotoxic activity of leaf extracts from seashore plants in subtropical Japan: isolation, quantification and cytotoxic action of (-)-deoxypodophyllotoxinQ44060267
Evidence for Common Mechanisms in the Transcriptional Control of Type II Nitric Oxide Synthase in Isolated HepatocytesQ61709083
Induction of nuclear factor kappa B after low-dose ionizing radiation involves a reactive oxygen intermediate signaling pathwayQ72748374
Inducible nitric oxide synthase in human diseasesQ77151701
IkappaB-NF-kappaB structures: at the interface of inflammation controlQ77726306
P433issue7
P921main subjectNF-κBQ411114
lipopolysaccharideQ421804
Anthriscus sylvestrisQ683490
deoxypodophyllotoxinQ27106380
P6954online access statusopen accessQ232932
P304page(s)1312-1315
P577publication date2008-07-01
P1433published inBiological and Pharmaceutical BulletinQ15754240
P1476titleThe naturally occurring flavolignan, deoxypodophyllotoxin, inhibits lipopolysaccharide-induced iNOS expression through the NF-kappaB activation in RAW264.7 macrophage cells
P478volume31

Reverse relations

cites work (P2860)
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