Cell-free DNA versus intact fetal cells for prenatal genetic diagnostics: what does the future hold?

scientific article published on 31 May 2015

Cell-free DNA versus intact fetal cells for prenatal genetic diagnostics: what does the future hold? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1586/14737159.2015.1051529
P698PubMed publication ID26027684

P2093author name stringRonald J Wapner
Karen Wou
Joe Leigh Simpson
Jessica L Feinberg
P2860cites workDNA Sequencing versus Standard Prenatal Aneuploidy ScreeningQ22250872
Isolation of fetal DNA from nucleated erythrocytes in maternal bloodQ24558688
Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartumQ24567463
Noninvasive prenatal aneuploidy testing of chromosomes 13, 18, 21, X, and Y, using targeted sequencing of polymorphic lociQ24632266
Fetal cells in the maternal circulation: feasibility for prenatal diagnosisQ33650187
DNA sequencing of maternal plasma to detect Down syndrome: an international clinical validation studyQ34029044
Genome-wide fetal aneuploidy detection by maternal plasma DNA sequencingQ34256640
Prenatal detection of fetal triploidy from cell-free DNA testing in maternal bloodQ34378350
Rapid clearance of fetal DNA from maternal plasmaQ34388637
Circulating trophoblastic cells provide genetic diagnosis in 63 fetuses at risk for cystic fibrosis or spinal muscular atrophyQ34418944
Expanding the scope of noninvasive prenatal testing: detection of fetal microdeletion syndromesQ34452242
Georg Schmorl on trophoblasts in the maternal circulationQ34566588
Procedure-related risk of miscarriage following amniocentesis and chorionic villus sampling: a systematic review and meta-analysisQ35209735
Analysis of cell-free DNA in maternal blood in screening for fetal aneuploidies: updated meta-analysisQ35552815
Rare chromosome abnormalities, prevalence and prenatal diagnosis rates from population-based congenital anomaly registers in EuropeQ35899367
Chromosomal microarray versus karyotyping for prenatal diagnosisQ36546668
Integration of noninvasive DNA testing for aneuploidy into prenatal care: what has happened since the rubber met the road?Q36787475
Noninvasive prenatal diagnosis of monogenic diseases by digital size selection and relative mutation dosage on DNA in maternal plasmaQ37000915
Noninvasive fetal genome sequencing: a primerQ37056703
The use of cell-free fetal nucleic acids in maternal blood for non-invasive prenatal diagnosisQ37306246
Turning the pyramid of prenatal careQ37851291
Diagnostic accuracy of non-invasive fetal RhD genotyping using cell-free fetal DNA: a meta analysisQ38178293
The promise of fetal cells in maternal bloodQ38467937
Noninvasive prenatal detection and selective analysis of cell-free DNA obtained from maternal blood: evaluation for trisomy 21 and trisomy 18.Q40028555
Microarray-based cell-free DNA analysis improves noninvasive prenatal testingQ40222706
Isolating fetal cells from maternal blood. Advances in prenatal diagnosis through molecular technologyQ40775838
Utilization of noninvasive prenatal testing: impact on referrals for diagnostic testingQ41060187
Fetal sex chromosome testing by maternal plasma DNA sequencing: clinical laboratory experience and biologyQ41609597
Combined screening for preeclampsia and small for gestational age at 11-13 weeks.Q43823700
Is it time to sound an alarm about false-positive cell-free DNA testing for fetal aneuploidy?Q43943228
Detection of microdeletion 22q11.2 in a fetus by next-generation sequencing of maternal plasmaQ44554684
Uptake of noninvasive prenatal testing at a large academic referral centerQ44999703
Cell-free DNA analysis for noninvasive examination of trisomyQ46784231
First-trimester or second-trimester screening, or both, for Down's syndromeQ46799629
Chromosome abnormalities detected by current prenatal screening and noninvasive prenatal testingQ46877513
Noninvasive prenatal testing: limitations and unanswered questionsQ47622449
Fetal cells in maternal blood: current and future perspectives.Q50876400
Enrichment of fetal trophoblast cells from the maternal peripheral blood followed by detection of fetal deoxyribonucleic acid with a nested X/Y polymerase chain reaction.Q51032871
Non-invasive early prenatal molecular diagnosis using retrieved transcervical trophoblast cells.Q51041376
Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18.Q51349861
Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the FetusQ56937251
Presence of fetal DNA in maternal plasma and serumQ57075132
Trophoblast retrieval and isolation from the cervix (TRIC) for noninvasive prenatal screening at 5 to 20 weeks of gestationQ58803674
Use of the Y Chromosome in Prenatal Sex DeterminationQ59074357
Fetal Nucleated Red Blood Cell Counts in Peripheral Blood of Mothers Bearing Down Syndrome FetusQ59135276
P433issue8
P304page(s)989-998
P577publication date2015-05-31
P1433published inExpert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcareQ15756305
P1476titleCell-free DNA versus intact fetal cells for prenatal genetic diagnostics: what does the future hold?
P478volume15

Reverse relations

cites work (P2860)
Q39756897Gestation related karyotype, QF-PCR and CGH-array failure rates in diagnostic amniocentesis.
Q36943659The impact of genomics on health outcomes, quality, and safety.
Q52613197Trophoblast retrieval and isolation from the cervix: origins of cervical trophoblasts and their potential value for risk assessment of ongoing pregnancies.

Search more.