The role of natural killer cells in periodontitis

scientific article published on October 2015

The role of natural killer cells in periodontitis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/PRD.12092
P698PubMed publication ID26252406

P2093author name stringLior Shapira
Stella Chaushu
Asaf Wilensky
P2860cites workA viral inhibitor of peptide transporters for antigen presentationQ46243412
IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumorsQ46391158
A Duffy binding-like domain is involved in the NKp30-mediated recognition of Plasmodium falciparum-parasitized erythrocytes by natural killer cellsQ46607865
NKp30 (NCR3) is a pseudogene in 12 inbred and wild mouse strains, but an expressed gene in Mus caroliQ47276299
Expression of human beta-defensins-1 and -2 peptides in unresolved chronic periodontitis.Q47321084
Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin productionQ47422836
TNFα mediates susceptibility to heat-induced apoptosis by protein phosphatase-mediated inhibition of the HSF1/hsp70 stress responseQ47614027
Comparison of relative TLR-2 and TLR-4 expression level of disease and healthy gingival tissue of smoking and non-smoking patients and periodontally healthy control patients.Q47689768
Relationship between clinical parameters and cytokine profiles in inflamed gingival tissue and serum samples from patients with chronic periodontitis.Q47996719
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Involvement of natural cytotoxicity receptors in human natural killer cell-mediated lysis of neuroblastoma and glioblastoma cell lines.Q55475545
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Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirusQ56956215
NKp44, a triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamilyQ22008826
Molecular and functional characterization of IRp60, a member of the immunoglobulin superfamily that functions as an inhibitory receptor in human NK cellsQ22010724
A Toll-like receptor recognizes bacterial DNAQ24290668
IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptorsQ24300426
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8Q24310398
Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicityQ24310824
Recognition of single-stranded RNA viruses by Toll-like receptor 7Q24568101
NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysisQ24647094
p46, a novel natural killer cell-specific surface molecule that mediates cell activationQ24647847
Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cellsQ24671834
Anti-TNF-alpha antibody allows healing of joint damage in polyarthritic transgenic miceQ24801075
Structure of the human NK cell triggering receptor NKp46 ectodomainQ27641939
Crystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptorsQ27641970
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3Q27860854
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processingQ28115772
Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoireQ28189785
The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46Q28204339
Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2)Q28207906
The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacteriumQ28208593
Proteolysis of macrophage inflammatory protein-1alpha isoforms LD78beta and LD78alpha by neutrophil-derived serine proteasesQ28236498
Characterization of inhibitory signaling motifs of the natural killer cell receptor Siglec-7: attenuated recruitment of phosphatases by the receptor is attributed to two amino acids in the motifsQ28306746
Innate or adaptive immunity? The example of natural killer cellsQ29615106
NK cell recognitionQ29615107
Toll-like receptors and innate immunityQ29615458
Innate immunityQ29618949
Oral microbial communities: biofilms, interactions, and genetic systemsQ30658118
Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cellsQ32102035
Molecular and genetic basis for strain-dependent NK1.1 alloreactivity of mouse NK cellsQ33245641
Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cellsQ33292289
Regulation of immune responses through inhibitory receptorsQ33652541
Cytokine profiling of macrophages exposed to Porphyromonas gingivalis, its lipopolysaccharide, or its FimA protein.Q33796702
Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interactionQ33886695
Natural cytotoxicity receptors that trigger human NK-cell-mediated cytolysis.Q33899290
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognitionQ33930537
Communication among oral bacteriaQ33970068
Induction of apoptotic cell death in peripheral blood mononuclear and polymorphonuclear cells by an oral bacterium, Fusobacterium nucleatumQ34003815
The natural cytotoxicity receptor 1 contribution to early clearance of Streptococcus pneumoniae and to natural killer-macrophage cross talkQ34009337
Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responsesQ34030338
Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.Q34178128
Direct recognition of Fusobacterium nucleatum by the NK cell natural cytotoxicity receptor NKp46 aggravates periodontal diseaseQ34211527
Roles of the NKG2D immunoreceptor and its ligandsQ34267094
Porphyromonas gingivalis lipopolysaccharide: an unusual pattern recognition receptor ligand for the innate host defense systemQ34335129
Ligands for natural killer cell receptors: redundancy or specificityQ34341435
Strategies for target cell recognition by natural killer cellsQ34341441
The UL16-binding proteins, a novel family of MHC class I-related ligands for NKG2D, activate natural killer cell functionsQ34341447
Human natural killer cell receptors and co-receptorsQ34341459
Periodontal microbial ecologyQ34413957
The biology of human natural killer-cell subsetsQ34430869
Molecular microbial diagnosisQ34758683
Regulatory pathways involved in the infection-induced production of IFN-gamma by NK cellsQ35035735
Human natural killer cell deficiencies and susceptibility to infectionQ35035745
Toll-like Receptors and Their Signaling MechanismsQ35585033
The dynamic life of natural killer cellsQ35698475
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cellsQ35971414
The bacterial etiology of destructive periodontal disease: current conceptsQ36056602
Evidence for discrete stages of human natural killer cell differentiation in vivoQ36228536
Human natural killer cells: Molecular mechanisms controlling NK cell activation and tumor cell lysisQ36234414
Antibacterial activity of human natural killer cellsQ36355907
Natural killer cell developmental pathways: a question of balance.Q36427341
Development of human lymphoid cellsQ36427345
Role of the NK cell-activating receptor CRACC in periodontitis.Q36646765
Functional subsets of mouse natural killer cellsQ36652157
HLA-C is the inhibitory ligand that determines dominant resistance to lysis by NK1- and NK2-specific natural killer cellsQ36738298
Inflammation and factors that may regulate inflammatory responseQ37232596
B cells from periodontal disease patients express surface Toll-like receptor 4Q37283826
Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunityQ37509338
Dendritic cells stimulated with Actinobacillus actinomycetemcomitans elicit rapid gamma interferon responses by natural killer cellsQ37521512
Herpesviral-bacterial interactions in periodontal diseasesQ37657655
Biology and pathogenesis of cytomegalovirus in periodontal diseaseQ38169797
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotidesQ38289912
Recognition of viral hemagglutinins by NKp44 but not by NKp30.Q38297211
Periodontal herpesviruses: prevalence, pathogenicity, systemic riskQ38562419
The role of natural killer cells in innate resistance to infectionQ38890804
Signaling by toll-like receptor 2 and 4 agonists results in differential gene expression in murine macrophages.Q39518721
Tumor immunoediting by NKp46.Q39713057
Immunohistological analysis of CD1a langerhans cells and CD57 natural killer cells in healthy and diseased human gingival tissue: A comparative studyQ39880824
Downregulation of class I major histocompatibility complex surface expression by varicella-zoster virus involves open reading frame 66 protein kinase-dependent and -independent mechanisms.Q40120151
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production.Q40395254
Carcinoembryonic antigen (CEA) inhibits NK killing via interaction with CEA-related cell adhesion molecule 1.Q40419886
Membrane-associated heparan sulfate proteoglycans are involved in the recognition of cellular targets by NKp30 and NKp46.Q40528376
Animal chamber models for study of host-parasite interactionsQ40687389
The role of the host response in periodontal disease progression: implications for future treatment strategiesQ40864530
The molecular basis of natural killer (NK) cell recognition and functionQ41183811
Density and localization of lymphocytes with natural-killer (NK) cell activity in periodontal biopsy specimens from patients with severe periodontitisQ41375937
Human natural killer cells isolated from peripheral blood do not rearrange T cell antigen receptor beta chain genesQ41446321
Adoptive transfer studies demonstrating the antiviral effect of natural killer cells in vivoQ41957577
Direct binding of human NK cell natural cytotoxicity receptor NKp44 to the surfaces of mycobacteria and other bacteria.Q42085198
Identification of four subsets of human CD3-CD16+ natural killer (NK) cells by the expression of clonally distributed functional surface molecules: correlation between subset assignment of NK clones and ability to mediate specific alloantigen recognQ42938918
The activating receptor NKp46 is essential for the development of type 1 diabetes.Q43214288
Comparison of NK-cell (Leu-7+ and Leu-11b+) populations in clinically healthy gingiva, chronic gingivitis and chronic adult periodontitisQ43563181
Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subsetQ43600819
The role of RgpA in the pathogenicity of Porphyromonas gingivalis in the murine periodontitis modelQ43677044
Immune response in asymptomatic smokersQ44110958
Cytokine expression in periodontal health and diseaseQ45297941
NK markers are expressed on a high percentage of virus-specific CD8+ and CD4+ T cellsQ45744756
P433issue1
P921main subjectperiodontitisQ520127
P1104number of pages14
P304page(s)128-141
P577publication date2015-10-01
P1433published inPeriodontology 2000Q15724648
P1476titleThe role of natural killer cells in periodontitis
P478volume69

Reverse relations

cites work (P2860)
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Q38562438T- and B-cell subsets in periodontitis
Q50233375The influence of KIR gene presence/absence polymorphisms on the development of periodontal disease in smokers and non-smokers.
Q38429375Transcriptome of Healthy Gingival Tissue from Edentulous Sites in Patients with a History of Aggressive Periodontitis