The genomic landscape of human immune-mediated diseases

scientific article published on 20 August 2015

The genomic landscape of human immune-mediated diseases is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1014266187
P356DOI10.1038/JHG.2015.99
P698PubMed publication ID26290150

P2093author name stringXin Wu
Huji Xu
Haiyan Chen
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
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Dickkopf-1 is a master regulator of joint remodelingQ79610564
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Guilt beyond a reasonable doubtQ80540702
Cutting edge: a variant of the IL-23R gene associated with inflammatory bowel disease induces loss of microRNA regulation and enhanced protein productionQ83289684
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Interleukin-12 and the regulation of innate resistance and adaptive immunityQ29614602
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibilityQ29614872
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1Q29614873
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related lociQ30417517
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritisQ30419111
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.Q30419116
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac diseaseQ30426720
Pervasive sharing of genetic effects in autoimmune diseaseQ30431030
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Genome-wide association study in a high-risk isolate for multiple sclerosis reveals associated variants in STAT3 geneQ33645905
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biologyQ33797864
The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humansQ33833964
Prioritizing candidate disease genes by network-based boosting of genome-wide association data.Q33887815
Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.Q33942125
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritisQ33982255
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IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokinesQ34090258
Immune-mediated disease genetics: the shared basis of pathogenesisQ34303522
Location of tumour necrosis factor alpha by immunohistochemistry in chronic inflammatory bowel diseaseQ34377789
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The common genetic hypothesis of autoimmune/inflammatory diseaseQ34607762
Th17 and natural Treg cell population dynamics in systemic lupus erythematosusQ34978528
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis riskQ35125868
Genetic interrelationship between insulin-dependent diabetes mellitus, the autoimmune thyroid diseases, and rheumatoid arthritisQ35200726
New Perspectives and Emerging Therapies for Immune-mediated Inflammatory DisordersQ35541936
The intricate role of complement component C4 in human systemic lupus erythematosusQ35627095
Obesity in autoimmune diseases: not a passive bystanderQ38237025
Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genesQ38518470
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Expression of IL-17, IL-23 and their receptors in minor salivary glands of patients with primary Sjögren's syndromeQ35676007
Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammationQ35791607
Gene map of the extended human MHC.Q35968433
Serum interleukin-17 & nitric oxide levels in patients with primary Sjögren's syndrome.Q36064302
Tumour necrosis factor inhibitors.Q36227991
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in miceQ36365451
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Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twinsQ36905127
A polymorphism in the coding region of Il12b promotes IL-12p70 and IL-23 heterodimer formationQ36905411
Immune-mediated diseases: where do we stand?Q36916194
IL-17/Th17 targeting: on the road to prevent chronic destructive arthritis?Q37015036
The epidermal growth factor receptor system in skin repair and inflammationQ37020092
Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritisQ37253521
Epidemiology of autoimmune diseases in DenmarkQ37278627
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.Q37298535
Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesisQ37316528
Immunochip analysis identifies multiple susceptibility loci for systemic sclerosisQ37441841
Interleukin-17 and its target genes: mechanisms of interleukin-17 function in diseaseQ37735334
The role of dendritic cells in the pathogenesis of systemic lupus erythematosusQ37737799
Epidemiology of immune-mediated inflammatory diseases: incidence, prevalence, natural history, and comorbidities.Q37740847
IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating diseaseQ37865163
The potential role of interleukin-17 in severe asthmaQ37902959
Biology and signal transduction pathways of the Lymphotoxin-αβ/LTβR systemQ37966050
Role of IL-17 in psoriasis and psoriatic arthritisQ37987880
Genetic variations in interleukin-12 related genes in immune-mediated diseasesQ38028141
Human genetics offers an emerging picture of common pathways and mechanisms in autoimmunityQ38049938
Th17 cells in type 1 diabetesQ38068028
Geographical variability and environmental risk factors in inflammatory bowel diseaseQ38075524
Mapping of immune-mediated disease genes.Q38120034
Genetic insights into common pathways and complex relationships among immune-mediated diseasesQ38126785
Inflammatory pathways in spondyloarthritisQ38130805
Genetics of autoimmunity: an update.Q38173983
Th17 and regulatory T cell balance in autoimmune and inflammatory diseasesQ38177967
Extraintestinal manifestations and complications in inflammatory bowel disease: from shared genetics to shared biological pathwaysQ38205103
The role of tumour necrosis factor in the pathogenesis of immune-mediated diseasesQ38207758
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)675-681
P577publication date2015-08-20
P1433published inJournal of Human GeneticsQ6295302
P1476titleThe genomic landscape of human immune-mediated diseases
P478volume60

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cites work (P2860)
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Q26741414The Gut Microbiota in Immune-Mediated Inflammatory Diseases
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