Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium

scientific article published on 22 July 2011

Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2011.07.020
P932PMC publication ID3180904
P698PubMed publication ID21803035
P5875ResearchGate publication ID51534326

P2093author name stringYan Xu
Jeffrey A Whitsett
Hans Michael Haitchi
James L Lessard
Sheila M Bell
Liqian Zhang
Angela Mendell
P2860cites workSonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidneyQ24313237
Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets familyQ24319000
The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiologyQ24647882
Intestinal-enriched Krüppel-like factor (Krüppel-like factor 5) is a positive regulator of cellular proliferationQ24653635
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resourcesQ27860739
Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epitheliumQ28255146
Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiationQ28264507
Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identitiesQ28277481
SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation.Q28506036
Dicer function is essential for lung epithelium morphogenesisQ28506135
Abnormal development of urogenital organs in Dlgh1-deficient miceQ28509669
Intestinal tumor progression is associated with altered function of KLF5Q28579165
Strain-dependent perinatal lethality of Ovol1-deficient mice and identification of Ovol2 as a downstream target of Ovol1 in skin epidermisQ28584785
Vesico-ureteric reflux and urinary tract development in the Pax2 1Neu+/- mouseQ28584800
FOXA1 and IRF-1 intermediary transcriptional regulators of PPARgamma-induced urothelial cytodifferentiationQ38288442
Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coliQ38293889
Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3.Q38308261
Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling.Q38507457
Kruppel-like factor 5 is required for perinatal lung morphogenesis and functionQ39965475
KLF5 promotes cell proliferation and tumorigenesis through gene regulation and the TSU-Pr1 human bladder cancer cell lineQ40368983
Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programmeQ40571674
Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development.Q40968789
Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal-epithelial interactionsQ41681909
Morphological observations on the epithelium of the developing urinary bladder of the mouse and rat.Q42435027
Differentiation of epithelial cells in the urinary tract.Q42475801
Krüppel-like factor 5 activates MEK/ERK signaling via EGFR in primary squamous epithelial cellsQ42505334
Fibroblast growth factor-7 regulates stratification of the bladder urotheliumQ42512490
Sonic Hedgehog mediator Gli2 regulates bladder mesenchymal patterningQ43882582
Overexpression of RET leads to vesicoureteric reflux in miceQ45029533
Serum response factor, its cofactors, and epithelial-mesenchymal signaling in urinary bladder smooth muscle formationQ46062455
Ontogeny of the rat bladder: smooth muscle and epithelial differentiationQ46440757
Differential expression of immunohistochemical markers in bladder smooth muscle and myofibroblasts, and the potential utility of desmin, smoothelin, and vimentin in staging of bladder carcinoma.Q51791900
Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs.Q51947004
A core Klf circuitry regulates self-renewal of embryonic stem cells.Q51964604
Embryology and genetics of primary vesico-ureteric reflux and associated renal dysplasia.Q51997234
Superficial cell differentiation during embryonic and postnatal development of mouse urothelium.Q52006928
Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development.Q52012848
Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutantsQ52214152
Identification of a unique transgenic mouse line that develops megabladder, obstructive uropathy, and renal dysfunctionQ79485448
Differential expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) and its coactivators steroid receptor coactivator-1 and PPAR-binding protein PBP in the brown fat, urinary bladder, colon, and breast of the mouseQ28585053
A homolog of Drosophila grainy head is essential for epidermal integrity in miceQ28585220
DeltaNp63 plays an anti-apoptotic role in ventral bladder developmentQ28586002
Tbx18 regulates the development of the ureteral mesenchymeQ28586369
Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchymeQ28587480
Lim 1 is required for nephric duct extension and ureteric bud morphogenesisQ28588807
The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiationQ28590746
Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epitheliumQ28594344
MatInspector and beyond: promoter analysis based on transcription factor binding sitesQ29616314
Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery.Q30549880
Cloning of human, murine, and marsupial keratin 7 and a survey of K7 expression in the mouseQ30858916
Direct targets of Klf5 transcription factor contribute to the maintenance of mouse embryonic stem cell undifferentiated state.Q33704459
p63 regulates commitment to the prostate cell lineageQ33913879
Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral refluxQ33925813
The LEF1/beta -catenin complex activates movo1, a mouse homolog of Drosophila ovo required for epidermal appendage differentiationQ34027866
Krüppel-like factor 5 mediates the transforming activity of oncogenic H-RasQ34312909
Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineumQ34618722
Rapid 3D phenotyping of cardiovascular development in mouse embryos by micro-CT with iodine stainingQ34691626
PPARgamma-regulated tight junction development during human urothelial cytodifferentiationQ34863027
Uroplakins in urothelial biology, function, and diseaseQ34973621
Pathogenesis of Renal Injury in the Megabladder Mouse: A Genetic Model of Congenital Obstructive NephropathyQ35064538
Krüppel-like factor 5 promotes mitosis by activating the cyclin B1/Cdc2 complex during oncogenic Ras-mediated transformationQ35112792
The epithelial-specific Ets factors occupy a unique position in defining epithelial proliferation, differentiation and carcinogenesisQ35190399
Comprehensive surgical treatment of prune belly syndrome: 17 years' experience with 32 patientsQ35921623
Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcriptionQ36117420
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases.Q36322834
Structural characterization of myofibroblasts in the bladderQ36335071
The function of suburothelial myofibroblasts in the bladderQ36925700
Gene discovery and vesicoureteric refluxQ37078188
Renal tract malformations: perspectives for nephrologistsQ37150737
C/EBP{alpha} is required for pulmonary cytoprotection during hyperoxiaQ37343865
The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cellsQ37365676
Interstitial cells in the urinary bladder--localization and function.Q37660268
Smooth muscle differentiation and patterning in the urinary bladderQ37764509
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)79-90
P577publication date2011-07-22
P1433published inDevelopmental BiologyQ3025402
P1476titleKruppel-like factor 5 is required for formation and differentiation of the bladder urothelium
P478volume358

Reverse relations

cites work (P2860)
Q36685508Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription
Q92675264Characterization of Krt19 CreERT allele for targeting the nucleus pulposus cells in the postnatal mouse intervertebral disc
Q34425051Critical role of Klf5 in regulating gene expression during post-eyelid opening maturation of mouse corneas
Q34358867Curcumin promotes KLF5 proteasome degradation through downregulating YAP/TAZ in bladder cancer cells.
Q34766615Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells
Q58779134Differential transcription factor expression by human epithelial cells of buccal and urothelial derivation
Q90288420Direct conversion of fibroblasts into urothelial cells that may be recruited to regenerating mucosa of injured urinary bladder
Q38803510Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer
Q37479778FOXA1, GATA3 and PPARɣ Cooperate to Drive Luminal Subtype in Bladder Cancer: A Molecular Analysis of Established Human Cell Lines
Q90563988Functional roles of Grainyhead-like transcription factors in renal development and disease
Q38098922Genetics of human congenital urinary bladder disease
Q33652158Heterarchy of transcription factors driving basal and luminal cell phenotypes in human urothelium
Q38310122Identification of ELF3 as an early transcriptional regulator of human urothelium
Q38801627KLF5 promotes cell migration by up-regulating FYN in bladder cancer cells.
Q34558936Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways
Q35708828Kruppel-like factor 5 (KLF5) is critical for conferring uterine receptivity to implantation
Q28593611Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium
Q38597258Krüppel-like factor 5 is essential for maintenance of barrier function in mouse colon
Q38789453On a FOX hunt: functions of FOX transcriptional regulators in bladder cancer.
Q27022848The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation
Q38752422Transcription Factor KLF5 Binds a Cyclin E1 Polymorphic Intronic Enhancer to Confer Increased Bladder Cancer Risk
Q90339620Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity
Q39008570miR-5195-3p Inhibits Proliferation and Invasion of Human Bladder Cancer Cells by Directly Targeting Oncogene KLF5.

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