The roles of CD147 in the progression of gliomas

scientific article published on 28 September 2015

The roles of CD147 in the progression of gliomas is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1586/14737140.2015.1092874
P698PubMed publication ID26414447

P2093author name stringZhinan Chen
Fei Fei
Zhou Fei
Sanzhong Li
P2860cites workExpression of emmprin (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas.Q55475249
Glioma cell extracellular matrix metalloproteinase inducer (EMMPRIN) (CD147) stimulates production of membrane-type matrix metalloproteinases and activated gelatinase A in co-cultures with brain-derived fibroblasts.Q55475300
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expressionQ24630430
MGMT gene silencing and benefit from temozolomide in glioblastomaQ27824832
Tumor angiogenesis: therapeutic implicationsQ27860595
CD147 Is a Signaling Receptor for Cyclophilin BQ28203139
Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouseQ28211495
Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblastsQ28216628
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trialQ29547224
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivoQ29614729
Angiogenesis as a therapeutic targetQ29619525
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenanceQ29620462
Basigin null mutant male mice are sterile and exhibit impaired interactions between germ cells and Sertoli cellsQ30411261
Expression of lactate/H⁺ symporters MCT1 and MCT4 and their chaperone CD147 predicts tumor progression in clear cell renal cell carcinoma: immunohistochemical and The Cancer Genome Atlas data analysesQ30487456
The MRC OX-47 antigen is a member of the immunoglobulin superfamily with an unusual transmembrane sequenceQ30976960
High expression of CD147 and MMP-9 is correlated with poor prognosis of triple-negative breast cancer (TNBC) patientsQ33762138
CD147 expression in human gastric cancer is associated with tumor recurrence and prognosisQ33825595
CD147 required for corneal endothelial lactate transportQ33975123
Overexpressions of RACK1 and CD147 Associated with Poor Prognosis in Stage T1 Pulmonary AdenocarcinomaQ34271830
Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinomaQ34485560
EMMPRIN Is an Independent Negative Prognostic Factor for Patients with Astrocytic GliomaQ34629446
Metalloproteinases and their inhibitors in angiogenesis.Q35571165
Extracellular Membrane-proximal Domain of HAb18G/CD147 Binds to Metal Ion-dependent Adhesion Site (MIDAS) Motif of Integrin β1 to Modulate Malignant Properties of Hepatoma CellsQ35762947
Cloning of cDNA for a novel mouse membrane glycoprotein (gp42): shared identity to histocompatibility antigens, immunoglobulins and neural-cell adhesion molecules.Q35956854
Human tumor cells induce angiogenesis through positive feedback between CD147 and insulin-like growth factor-IQ36109653
High glycolysis in gliomas despite low hexokinase transcription and activity correlated to chromosome 10 lossQ36136081
Breaching the diffusion barrier that compartmentalizes the transmembrane glycoprotein CE9 to the posterior-tail plasma membrane domain of the rat spermatozoonQ36232375
CD147 immunoglobulin superfamily receptor function and role in pathologyQ36398938
Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targetsQ36544108
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosisQ36611964
Extent of resection of glioblastoma revisited: personalized survival modeling facilitates more accurate survival prediction and supports a maximum-safe-resection approach to surgeryQ36925174
Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistanceQ36976346
EMMPRIN expression positively correlates with WHO grades of astrocytomas and meningiomasQ37097921
CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cellsQ37396842
Anti-EMMPRIN monoclonal antibody as a novel agent for therapy of head and neck cancer.Q37484367
The role of EMMPRIN expression in ovarian epithelial carcinomasQ37505550
Biology of angiogenesis and invasion in gliomaQ37533625
S100A9 Is a Novel Ligand of EMMPRIN That Promotes Melanoma MetastasisQ38320167
Glycomic alterations are associated with multidrug resistance in human leukemiaQ38325420
HAb18G/CD147 is involved in TGF-β-induced epithelial-mesenchymal transition and hepatocellular carcinoma invasionQ38973523
EMMPRIN reduction via scFv-M6-1B9 intrabody affects α3β1-integrin and MCT1 functions and results in suppression of progressive phenotype in the colorectal cancer cell line Caco-2.Q38985433
CD147 promotes melanoma progression through hypoxia-induced MMP2 activation.Q39088478
RNA interference targeting CD147 inhibits the invasion of human cervical squamous carcinoma cells by downregulating MMP-9.Q39174612
Clinical impact of HAb18G/CD147 expression in esophageal squamous cell carcinomaQ39500859
Up-regulated EMMPRIN/CD147 protein expression might play a role in colorectal carcinogenesis and its subsequent progression without an alteration of its glycosylation and mRNA levelQ39698021
Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapyQ39830942
Expression and clinical significance of CD147 in genitourinary carcinomasQ39872877
CD147 impacts angiogenesis and metastasis formation.Q39892358
RNA interference targeting the CD147 induces apoptosis of multi-drug resistant cancer cells related to XIAP depletionQ39903350
A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysisQ39941968
Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231.Q40136574
A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanomaQ40200798
Deglycosylation of CD147 down-regulates Matrix Metalloproteinase-11 expression and the adhesive capability of murine hepatocarcinoma cell HcaF in vitroQ40271394
High incidence of EMMPRIN expression in human tumorsQ40276050
Matrix metalloproteinase 2 is associated with stable and matrix metalloproteinases 8 and 9 with vulnerable carotid atherosclerotic lesions: a study in human endarterectomy specimen pointing to a role for different extracellular matrix metalloproteinQ40341617
Inhibition of basigin expression in glioblastoma cell line via antisense RNA reduces tumor cell invasion and angiogenesisQ40406438
Glioma invasion in the central nervous systemQ41131785
Glycolysis as primary energy source in tumor cell chemotaxisQ41711023
Neurothelin: an inducible cell surface glycoprotein of blood-brain barrier-specific endothelial cells and distinct neuronsQ41939143
FDA accelerated approval benefits glioblastomaQ42787201
Distribution of the integral plasma membrane glycoprotein CE9 (MRC OX-47) among rat tissues and its induction by diverse stimuli of metabolic activationQ42821962
Expression of HAb18G is associated with tumor progression and prognosis of breast carcinomaQ43137955
Prognostic significance of CD147 in patients with glioblastomaQ43686572
CD147 expression indicates unfavourable prognosis in prostate cancerQ43968053
The impact of improved treatment strategies on overall survival in glioblastoma patientsQ45256790
EMMPRIN/CD147 expression is associated with disease-free survival of patients with colorectal cancerQ45386247
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastomaQ46796397
Prognostic significance of let-7b expression in breast cancer and correlation to its target gene of BSG expressionQ46968801
HAb18G (CD147), a cancer-associated biomarker and its role in cancer detectionQ47811362
¹⁸F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomasQ48673004
Clinical implications and prognostic value of EMMPRIN/CD147 and MMP2 expression in pediatric gliomasQ48923618
Correlation between expression of extracellular matrix metalloproteinase inducer and matrix metalloproteinase-2 and cervical lymph node metastasis of nasopharyngeal carcinomaQ51074511
A randomized controlled trial of Licartin for preventing hepatoma recurrence after liver transplantationQ51080130
Upregulation of HAb18G/CD147 in activated human umbilical vein endothelial cells enhances the angiogenesisQ51816576
CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathwayQ53483909
Phase 2 trial of hypofractionated high-dose intensity modulated radiation therapy with concurrent and adjuvant temozolomide for newly diagnosed glioblastoma.Q55461227
Extracellular Matrix Metalloproteinase Inducer is a Negative Prognostic Factor of Pediatric MedulloblastomaQ55463284
P433issue11
P304page(s)1351-1359
P577publication date2015-09-28
P1433published inExpert Review of Anticancer TherapyQ2999044
P1476titleThe roles of CD147 in the progression of gliomas
P478volume15

Reverse relations

cites work (P2860)
Q64108170Shikonin inhibits proliferation and induces apoptosis in glioma cells via downregulation of CD147
Q38739580The effects of CD147 on the cell proliferation, apoptosis, invasion, and angiogenesis in glioma
Q48283352The role of extracellular matrix metalloproteinase inducer glycosylation in regulating matrix metalloproteinases in periodontitis.