New approaches for direct conversion of patient fibroblasts into neural cells

scientific article published on 14 October 2015

New approaches for direct conversion of patient fibroblasts into neural cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BRAINRES.2015.10.012
P932PMC publication ID4834061
P698PubMed publication ID26475975

P50authorPooja HorQ96065173
P2093author name stringJustin K Ichida
Suhasni Gopalakrishnan
P2860cites workDirect conversion of fibroblasts to functional neurons by defined factorsQ24641912
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutationQ26269852
Rapid single-step induction of functional neurons from human pluripotent stem cellsQ26269862
Direct lineage conversion of terminally differentiated hepatocytes to functional neuronsQ26269878
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cellsQ26269888
Induction of human neuronal cells by defined transcription factorsQ26269896
Generation of induced neuronal cells by the single reprogramming factor ASCL1Q26269984
Directing astroglia from the cerebral cortex into subtype specific functional neuronsQ27324490
Induction of pluripotent stem cells from adult human fibroblasts by defined factorsQ27860967
Generation of germline-competent induced pluripotent stem cellsQ28131699
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factorsQ28589872
Cerebral organoids model human brain development and microcephalyQ28973619
Epigenetic memory in induced pluripotent stem cellsQ29547892
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cellsQ29615870
Self-organizing optic-cup morphogenesis in three-dimensional cultureQ29616181
Single Transcription Factor Conversion of Human Blood Fate to NPCs with CNS and PNS Developmental Capacity.Q50585607
Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia.Q50670391
Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cellsQ57962393
Generation of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortexQ83366745
Direct generation of functional dopaminergic neurons from mouse and human fibroblastsQ29616184
Immunogenicity of induced pluripotent stem cellsQ29616185
Pluripotent stem cells induced from mouse somatic cells by small-molecule compoundsQ29616608
Hierarchical mechanisms for direct reprogramming of fibroblasts to neuronsQ29871108
Chemical approaches to stem cell biology and therapeuticsQ30431314
Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factorsQ30514064
Remote control of induced dopaminergic neurons in parkinsonian rats.Q30581671
Ectopic expression of neurogenin 2 alone is sufficient to induce differentiation of embryonic stem cells into mature neuronsQ31066354
Generation of neural progenitor cells by chemical cocktails and hypoxiaQ33701798
Small molecules enable highly efficient neuronal conversion of human fibroblastsQ34031414
Turning straw into gold: directing cell fate for regenerative medicineQ34169386
Direct reprogramming of mouse fibroblasts to neural progenitorsQ34180572
Specification of transplantable astroglial subtypes from human pluripotent stem cellsQ34186625
Direct conversion of human fibroblasts to dopaminergic neuronsQ34190302
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors.Q34196432
MicroRNA-mediated conversion of human fibroblasts to neurons.Q34200249
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditionsQ34204810
Direct reprogramming of fibroblasts into neural stem cells by defined factorsQ34263432
Direct conversion of fibroblasts into stably expandable neural stem cellsQ34263438
Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factorQ34280164
Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult miceQ34331873
Generation of induced neurons via direct conversion in vivoQ34335374
Generation of oligodendroglial cells by direct lineage conversion.Q34339119
Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.Q34339127
Generation of inner ear sensory epithelia from pluripotent stem cells in 3D cultureQ34356634
In vivo reprogramming of astrocytes to neuroblasts in the adult brainQ34372623
In vivo conversion of astrocytes to neurons in the injured adult spinal cordQ34406755
Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cellsQ34451120
Generation of human striatal neurons by microRNA-dependent direct conversion of fibroblastsQ34469252
CellNet: network biology applied to stem cell engineeringQ34520877
Self-formation of optic cups and storable stratified neural retina from human ESCs.Q34639338
Sox2-mediated conversion of NG2 glia into induced neurons in the injured adult cerebral cortex.Q34684480
Efficient generation of integration-free ips cells from human adult peripheral blood using BCL-XL together with Yamanaka factorsQ34738075
Direct conversion of fibroblasts into functional astrocytes by defined transcription factorsQ34980759
Variation in the safety of induced pluripotent stem cell linesQ34991636
Directed differentiation of functional astroglial subtypes from human pluripotent stem cellsQ35414493
Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.Q35497588
Functional integration of dopaminergic neurons directly converted from mouse fibroblastsQ35534141
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.Q35600035
MicroRNA-Mediated In Vitro and In Vivo Direct Conversion of Astrocytes to Neuroblasts.Q35648513
Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells.Q35732928
Selective conversion of fibroblasts into peripheral sensory neuronsQ35738803
Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional NeuronsQ35740223
Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small MoleculesQ35740228
Transcriptional Mechanisms of Proneural Factors and REST in Regulating Neuronal Reprogramming of AstrocytesQ35871829
Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage ConversionQ35902185
Astrocytes and disease: a neurodevelopmental perspectiveQ35945056
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal deathQ36246294
Environmental impact on direct neuronal reprogramming in vivo in the adult brainQ37206992
Reprogramming of human primary somatic cells by OCT4 and chemical compoundsQ37267824
Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity.Q37288224
Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neuronsQ37350844
Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALSQ37495227
In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease modelQ37668698
The stem cell potential of glia: lessons from reactive gliosisQ37830315
Direct reprogramming of adult somatic cells into other lineages: past evidence and future perspectivesQ38050228
All roads lead to induced pluripotent stem cells: the technologies of iPSC generation.Q38187715
Direct lineage reprogramming: strategies, mechanisms, and applicationsQ38346530
In vivo reprogramming for tissue repair.Q38365611
Conversion of mouse and human fibroblasts into functional spinal motor neuronsQ38651033
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuitsQ39211798
Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cellsQ39433954
Dissecting engineered cell types and enhancing cell fate conversion via CellNetQ42035941
Induction of retinal ganglion-like cells from fibroblasts by adenoviral gene deliveryQ42283759
Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors.Q42560019
An indirect approach to generating specific human cell typesQ42747193
Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cellsQ42762269
White matter from fibroblasts.Q42769367
Drug screening for ALS using patient-specific induced pluripotent stem cellsQ42820289
Reprogramming of pericyte-derived cells of the adult human brain into induced neuronal cells.Q48348076
Reprogramming of postnatal astroglia of the mouse neocortex into functional, synapse-forming neuronsQ48797632
Generation of multipotent induced neural crest by direct reprogramming of human postnatal fibroblasts with a single transcription factor.Q50450522
P407language of work or nameEnglishQ1860
P304page(s)2-13
P577publication date2015-10-16
P1433published inBrain ResearchQ4955782
P1476titleNew approaches for direct conversion of patient fibroblasts into neural cells
P478volume1656

Reverse relations

cites work (P2860)
Q58595040Comparative genomic analysis of embryonic, lineage-converted, and stem cell-derived motor neurons
Q47868914Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells
Q64059931Direct conversion of fibroblasts to osteoblasts as a novel strategy for bone regeneration in elderly individuals
Q64040152Expanding the Boundaries of RNA Sequencing as a Diagnostic Tool for Rare Mendelian Disease
Q40772027Functionalizing Ascl1 with Novel Intracellular Protein Delivery Technology for Promoting Neuronal Differentiation of Human Induced Pluripotent Stem Cells
Q38921974Network Reconstruction Reveals that Valproic Acid Activates Neurogenic Transcriptional Programs in Adult Brain Following Traumatic Injury
Q55446282Reprogramming of mouse fibroblasts into neural lineage cells using biomaterials.

Search more.