scholarly article | Q13442814 |
P50 | author | Tomasz Baczek | Q56849433 |
Marcin Koba | Q61994361 | ||
P2860 | cites work | The relevance of enzymatic oxidation by horseradish peroxidase to antitumour potency of imidazoacridinone derivatives | Q77561034 |
Molecular mechanism of the enzymatic oxidation investigated for imidazoacridinone antitumor drug, C-1311 | Q79175571 | ||
Antitumour imidazoacridone C-1311 induces cell death by mitotic catastrophe in human colon carcinoma cells | Q81400239 | ||
Induction of unique structural changes in guanine-rich DNA regions by the triazoloacridone C-1305, a topoisomerase II inhibitor with antitumor activities | Q24811057 | ||
Cell killing by the novel imidazoacridinone antineoplastic agent, C-1311, is inhibited at high concentrations coincident with dose-differentiated cell cycle perturbation | Q36136247 | ||
Preclinical evaluation of novel imidazoacridinone derivatives with potent activity against experimental colorectal cancer | Q36136293 | ||
Cellular uptake, cytotoxicity and DNA-binding studies of the novel imidazoacridinone antineoplastic agent C1311. | Q36619630 | ||
Mitoxantrone and ametantrone induce interstrand cross-links in DNA of tumour cells | Q36641685 | ||
Pharmacological and toxicological aspects of new imidazoacridinone antitumor agents | Q36797525 | ||
Comparative cytotoxicity of C-1311 in colon cancer in vitro and in vivo using the hollow fiber assay | Q40036736 | ||
Comparative evaluation of C1311 cytotoxic activity and interference with cell cycle progression in a panel of human solid tumour and leukaemia cell lines. | Q40085052 | ||
C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells. | Q40137056 | ||
Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305. | Q40232516 | ||
Cell growth inhibition, G2M cell cycle arrest and apoptosis induced by the imidazoacridinone C1311 in human tumour cell lines | Q40778077 | ||
In vivo metabolism of the antitumor imidazoacridinone C1311 in the mouse and in vitro comparison with humans. | Q42536366 | ||
The antitumor triazoloacridone C-1305 is a topoisomerase II poison with unusual properties | Q42827284 | ||
Interactions of antitumor triazoloacridinones with DNA. | Q42829013 | ||
Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout cells to antitumor triazoloacridone C-1305 is associated with permanent G2 cell cycle arrest | Q44961884 | ||
Development and validation of an LC-UV method for the quantification and purity determination of the novel anticancer agent C1311 and its pharmaceutical dosage form | Q46495454 | ||
Pharmaceutical development of a parenteral lyophilised dosage form for the novel anticancer agent C1311. | Q46826201 | ||
Compatibility and stability of the novel anti-cancer agent C1311 in infusion devices and its in vitro biocompatibility | Q46929841 | ||
Sequential induction of mitotic catastrophe followed by apoptosis in human leukemia MOLT4 cells by imidazoacridinone C-1311. | Q46960032 | ||
Experimental antitumor activity and toxicity of the selected triazolo- and imidazoacridinones. | Q51040409 | ||
Retention prediction of peptides based on uninformative variable elimination by partial least squares. | Q51938282 | ||
QSAR of acridines, III. Structure-activity relationship for antitumour imidazoacridinones and intercorrelations between in vivo and in vitro tests. | Q52320015 | ||
Chromophore-modified antineoplastic imidazoacridinones. Synthesis and activity against murine leukemias | Q67733861 | ||
8-Substituted 5-[(aminoalkyl)amino]-6H-v-triazolo[4,5,1-de]acridin-6-ones as potential antineoplastic agents. Synthesis and biological activity | Q68560515 | ||
Inhibition of DNA topoisomerase II by imidazoacridinones, new antineoplastic agents with strong activity against solid tumors | Q71061316 | ||
Structure-activity relationship for antineoplastic imidazoacridinones: synthesis and antileukemic activity in vivo | Q71176181 | ||
Intercalation of imidazoacridinones to DNA and its relevance to cytotoxic and antitumor activity | Q74084156 | ||
The intercalation of imidazoacridinones into DNA induces conformational changes in their side chain | Q74231882 | ||
Pharmacokinetics and tissue distribution of the imidazoacridinone C1311 in tumour-bearing mice | Q77408664 | ||
P433 | issue | 8 | |
P304 | page(s) | 1385-1393 | |
P577 | publication date | 2010-11-17 | |
P1433 | published in | Medicinal Chemistry Research | Q3304000 |
P1476 | title | Physicochemical interaction of antitumor acridinone derivatives with DNA in view of QSAR studies | |
P478 | volume | 20 |
Q38213469 | Acridine and its derivatives: a patent review (2009 - 2013). |
Q34718278 | Acridone derivative 8a induces oxidative stress-mediated apoptosis in CCRF-CEM leukemia cells: application of metabolomics in mechanistic studies of antitumor agents |
Q49417795 | Acridone suppresses the proliferation of human breast cancer cells in vitro via ATP-binding cassette subfamily G member 2. |
Q38986162 | Synthesis, characterization and biological evaluation of carboranylmethylbenzo[b]acridones as novel agents for boron neutron capture therapy |
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