Toward a Better Understanding of the Complexity of Cancer Drug Resistance

scientific article

Toward a Better Understanding of the Complexity of Cancer Drug Resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1146/ANNUREV-PHARMTOX-010715-103111
P698PubMed publication ID26514196

P50authorMichael M. GottesmanQ6832389
P2093author name stringJean-Pierre Gillet
Orit Lavi
Matthew D Hall
P2860cites workMelanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulationQ24629474
Mutations of the BRAF gene in human cancerQ27860760
P407language of work or nameEnglishQ1860
P304page(s)85-102
P577publication date2015-10-28
P1433published inAnnual Review of Pharmacology and ToxicologyQ567365
P1476titleToward a Better Understanding of the Complexity of Cancer Drug Resistance
P478volume56

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cites work (P2860)
Q90083275A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein
Q37718215A piRNA-like Small RNA Induces Chemoresistance to Cisplatin-Based Therapy by Inhibiting Apoptosis in Lung Squamous Cell Carcinoma
Q92961815Anaplastic Lymphoma Kinase Confers Resistance to BRAF Kinase Inhibitors in Melanoma
Q38557650Applying nanomedicine in maladaptive inflammation and angiogenesis
Q42371843Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays
Q48112768CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy
Q46900302Cancer Immunotherapy Getting Brainy: Visualizing the Distinctive CNS Metastatic Niche to Illuminate Therapeutic Resistance.
Q92703787Cancer Stem Cells and Targeting Strategies
Q97643334Chemical strategies to overcome resistance against targeted anticancer therapeutics
Q92701884Deep Sequencing Analysis Reveals Distinctive Non-Coding RNAs When Comparing Tumor Multidrug-Resistant Cells and Extracellular Vesicles with Drug-Sensitive Counterparts
Q92156719Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer
Q91844985DrugComb: an integrative cancer drug combination data portal
Q90334544Effects of Natural Polyphenols on the Expression of Drug Efflux Transporter P-Glycoprotein in Human Intestinal Cells
Q39603486Emergent properties of a computational model of tumour growth
Q95840696Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer
Q92408754European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects
Q95276446Exosomal MicroRNA-221-3p Confers Adriamycin Resistance in Breast Cancer Cells by Targeting PIK3R1
Q37564876Exploring conformational equilibria of a heterodimeric ABC transporter.
Q52670051Identification of COL4A1 as a potential gene conferring trastuzumab resistance in gastric cancer based on bioinformatics analysis.
Q49382862Immunological hallmarks of cis-DDP-resistant Lewis lung carcinoma cells.
Q36125103Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death
Q55656421Integrative Analysis of Dysregulated lncRNA-Associated ceRNA Network Reveals Functional lncRNAs in Gastric Cancer.
Q92382750Knockdown of lncRNA MIAT inhibits proliferation and cisplatin resistance in non-small cell lung cancer cells by increasing miR-184 expression
Q55282022Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer.
Q50076078Leveraging Chemotype-Specific Resistance for Drug Target Identification and Chemical Biology
Q97569963LncRNA PSMA3-AS1 Promotes Lung Cancer Growth and Invasion via Sponging MiR-4504
Q58608801Machine learning predicts individual cancer patient responses to therapeutic drugs with high accuracy
Q60912359Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells-Deciphering Novel Potential Targets for a Cell Sensitization
Q93017361Microtubule-targeting anticancer drug eribulin induces drug efflux transporter P-glycoprotein
Q42798231Molecular Imaging of P-glycoprotein in Chemoresistant Tumors Using a Dual-Modality PET/Fluorescence Probe.
Q100534618Molecular and cellular paradigms of multidrug resistance in cancer
Q90608550N6-methyladenosine-induced ERRγ triggers chemoresistance of cancer cells through upregulation of ABCB1 and metabolic reprogramming
Q33772186Nanoparticle-based drug delivery systems: What can they really do in vivo?
Q57033051P-Glycoprotein-Targeted Photothermal Therapy of Drug-Resistant Cancer Cells Using Antibody-Conjugated Carbon Nanotubes
Q57287520P-glycoprotein targeted photodynamic therapy of chemoresistant tumors using recombinant Fab fragment conjugates
Q60930267P-glycoprotein-targeted photodynamic therapy boosts cancer nanomedicine by priming tumor microenvironment
Q64279888PYK2 promotes HER2-positive breast cancer invasion
Q37624466Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation
Q39820811Pharmacological Development of Target-Specific Delocalized Lipophilic Cation-Functionalized Carboranes for Cancer Therapy
Q94545721Phenotypic screening using large-scale genomic libraries to identify drug targets for the treatment of cancer
Q52343895Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes.
Q92533682Polytherapy and Targeted Cancer Drug Resistance
Q89824200Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms
Q38918710Proteogenomic studies on cancer drug resistance: towards biomarker discovery and target identification
Q92127589Proteomic Analysis of Breast Cancer Resistance to the Anticancer Drug RH1 Reveals the Importance of Cancer Stem Cells
Q48246978Recent advances in the biology and therapy of medullary thyroid carcinoma.
Q88404555Reversion of Multidrug Resistance by Co-Encapsulation of Doxorubicin and Metformin in Poly(lactide-co-glycolide)-d-α-tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles
Q52593092Revisiting the role of ABC transporters in multidrug-resistant cancer.
Q55465529Short- and long-term evolution in our arms race with cancer: Why the war on cancer is winnable.
Q64073261Structure and Anti-Tumor Activities of Exopolysaccharides from Roberts
Q64912838TNF-α Modulates P-Glycoprotein Expression and Contributes to Cellular Proliferation via Extracellular Vesicles.
Q48168156Targeting P-glycoprotein and SORCIN: Dihydromyricetin strengthens anti-proliferative efficiency of adriamycin via MAPK/ERK and Ca2+ -mediated apoptosis pathways in MCF-7/ADR and K562/ADR.
Q37702768Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin
Q58773220Th1-Biased Immunomodulation and In Vivo Antitumor Effect of a Novel Piperine Analogue
Q60914167The Adaptive Complexity of Cancer
Q90303582The Emerging Role of the SLCO1B3 Protein in Cancer Resistance
Q58694197The Network of Non-coding RNAs in Cancer Drug Resistance
Q39196784The therapeutic potential of targeting ABC transporters to combat multi-drug resistance.
Q96576495Theoretical insights on helix repacking as the origin of P-glycoprotein promiscuity
Q47216949Towards Comprehension of the ABCB1/P-Glycoprotein Role in Chronic Myeloid Leukemia
Q91906475Transcription factor Nrf2 induces the up-regulation of lncRNA TUG1 to promote progression and adriamycin resistance in urothelial carcinoma of the bladder
Q33754032microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression

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