Growth factor regulation of growth factor production by multiple gene transfer to chondrocytes

scientific article

Growth factor regulation of growth factor production by multiple gene transfer to chondrocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/08977194.2012.750652
P932PMC publication ID3976180
P698PubMed publication ID23302100

P2093author name stringGeorge J Eckert
Shuiliang Shi
Stephen B Trippel
Scott Mercer
P2860cites workPrevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation --- United States, 2007-2009.Q34142378
Basic fibroblast growth factor inhibits the anabolic activity of insulin-like growth factor 1 and osteogenic protein 1 in adult human articular chondrocytesQ34693804
Cartilage morphogenetic proteins: role in joint development, homoeostasis, and regenerationQ35553517
Gene-based approaches for the repair of articular cartilageQ35629558
Synergistic effect of IGF-1 and OP-1 on matrix formation by normal and OA chondrocytes cultured in alginate beadsQ35846551
Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latencyQ37039648
Concepts in gene therapy for cartilage repair.Q37099568
Growth factor transgenes interactively regulate articular chondrocytesQ37715441
Growth factor actions on articular cartilageQ40526506
Effect of transfection strategy on growth factor overexpression by articular chondrocytesQ41846147
Regulation of articular chondrocyte aggrecan and collagen gene expression by multiple growth factor gene transferQ41915703
Contrasting modulation by transforming growth factor-beta-1 of insulin-like growth factor-I production in osteoblasts and chondrocytesQ41971507
Growth factor regulation of growth factors in articular chondrocytesQ42097596
Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explantsQ42505298
Transforming growth factor beta regulates the metabolism of proteoglycans in bovine cartilage organ culturesQ42513738
Acceleration of articular cartilage repair by combined gene transfer of human insulin-like growth factor I and fibroblast growth factor-2 in vivoQ42826063
Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilageQ42855002
Transforming growth factor beta: an autocrine regulator of chondrocytesQ43572826
Exogenous insulin-like growth factor-I stimulates an autoinductive IGF-I autocrine/paracrine response in chondrocytesQ43595031
Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explantsQ43783103
The combination of insulin-like growth factor 1 and osteogenic protein 1 promotes increased survival of and matrix synthesis by normal and osteoarthritic human articular chondrocytesQ44541021
Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vectorQ45527212
Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine modelQ45868543
Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I).Q45882616
Growth factor stimulation of adult articular cartilageQ46849942
Differential expression of TGF beta isoforms by human articular chondrocytes in response to growth factorsQ46988088
Bone morphogenetic protein (BMP)-2 enhances the expression of type II collagen and aggrecan in chondrocytes embedded in alginate beadsQ47286014
Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytesQ64380332
Transforming growth factor-beta and fibroblast growth factor act synergistically to inhibit collagen II synthesis through a mechanism involving regulatory DNA sequencesQ69723451
Effect of Transforming Growth Factor-β on the Insulin-like Growth Factor-I Autocrine/Paracrine Axis in Cultured Rat Articular ChondrocytesQ71655933
Recombinant human osteogenic protein 1 is a potent stimulator of the synthesis of cartilage proteoglycans and collagens by human articular chondrocytesQ71766997
Basic fibroblast growth factor regulates expression of growth factors in rat epiphyseal chondrocytesQ73866491
Articular cartilage repair and transplantationQ77093059
Beneficial effect of basic fibroblast growth factor on the repair of full-thickness defects in rabbit articular cartilageQ77957320
Enhanced repair of extensive articular defects by insulin-like growth factor-I-laden fibrin compositesQ78165069
Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2Q80931371
Promotion of the intrinsic damage-repair response in articular cartilage by fibroblastic growth factor-2Q81794212
P433issue1
P304page(s)32-38
P577publication date2013-01-09
P1433published inGrowth Factors JournalQ5611728
P1476titleGrowth factor regulation of growth factor production by multiple gene transfer to chondrocytes
P478volume31

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cites work (P2860)
Q35414105Effects of phosphorylatable short peptide-conjugated chitosan-mediated IL-1Ra and igf-1 gene transfer on articular cartilage defects in rabbits
Q41982504Endogenous versus exogenous growth factor regulation of articular chondrocytes
Q38642703Gene therapy for human osteoarthritis: principles and clinical translation
Q37004050Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology.
Q64064105NNS-Conjugated Chitosan Mediated IGF-1 and miR-140 Overexpression in Articular Chondrocytes Improves Cartilage Repair
Q35670745The Axolotl Fibula as a Model for the Induction of Regeneration across Large Segment Defects in Long Bones of the Extremities
Q42269793rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

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