review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Nagaraja Haleagrahara | Q42087278 |
P2093 | author name string | Ammu Kutty Radhakrishnan | |
Kasthuri Bai Magalingam | |||
P2860 | cites work | Interaction of metal-complexing compounds with lymphocytes and lymphoid cell lines | Q45096425 |
Analysis of gene expression changes in a cellular model of Parkinson disease | Q45223326 | ||
The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links alpha-synuclein causing rapid formation of stable oligomers | Q46205788 | ||
Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation | Q46295708 | ||
Modulation of radiation-induced alteration in the antioxidant status of mice by naringin | Q46528360 | ||
A comprehensive evaluation of the enzymatic and nonenzymatic antioxidant systems in childhood asthma. | Q46591384 | ||
Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity | Q46750098 | ||
Protective effect of hesperidin in a model of Parkinson's disease induced by 6-hydroxydopamine in aged mice | Q46830526 | ||
Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease | Q46870422 | ||
Oestradiol or genistein rescues neurons from amyloid beta-induced cell death by inhibiting activation of p38. | Q46887312 | ||
Neuroprotective and neurorescue effect of black tea extract in 6-hydroxydopamine-lesioned rat model of Parkinson's disease | Q46946554 | ||
Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits | Q48101192 | ||
Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptors | Q48157309 | ||
Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains | Q48187073 | ||
Estradiol upregulates Bcl-2 expression in adult brain neurons | Q48484270 | ||
Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondria-dependent apoptosis pathways and reactive oxygen induced-NF-κB activation in a cerebral ischemia mouse model. | Q48575817 | ||
Theaflavin, a black tea polyphenol, protects nigral dopaminergic neurons against chronic MPTP/probenecid induced Parkinson's disease. | Q48802775 | ||
Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome. | Q50485503 | ||
Chemical structure-dependent differential effects of flavonoids on the catalase activity as evaluated by a chemiluminescent method. | Q50699231 | ||
Catechin attenuates behavioral neurotoxicity induced by 6-OHDA in rats. | Q50742343 | ||
Therapeutic effect of emodin on collagen-induced arthritis in mice. | Q50943499 | ||
Myricetin attenuated MPP(+)-induced cytotoxicity by anti-oxidation and inhibition of MKK4 and JNK activation in MES23.5 cells. | Q54591838 | ||
Role of mitochondria in oxidative stress and ageing | Q57014212 | ||
TLR signaling tailors innate immune responses in human microglia and astrocytes | Q57041985 | ||
Antioxidant properties of polyphenol-rich cocoa products industrially processed | Q58817366 | ||
Review: Health Effects of Cocoa Flavonoids | Q59158122 | ||
Mitochondrial complex I deficiency in Parkinson's disease | Q69370277 | ||
Etiology of Parkinson's Disease | Q73260280 | ||
Mitochondrial dysfunction in Parkinson's disease | Q80228162 | ||
Antioxidant properties of quercetin | Q83738942 | ||
Etiology of Parkinson's disease | Q83826099 | ||
Kaempferol regulates MAPKs and NF-κB signaling pathways to attenuate LPS-induced acute lung injury in mice | Q84628701 | ||
Alzheimer disease | Q85013370 | ||
Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers | Q21198861 | ||
Pesticide exposure and Parkinson's disease: Epidemiological evidence of association | Q22251266 | ||
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms | Q24312029 | ||
The role of free radicals in the aging brain and Parkinson's Disease: convergence and parallelism | Q26852148 | ||
Do antioxidants impair signaling by reactive oxygen species and lipid oxidation products? | Q26864665 | ||
Molecular targets of dietary polyphenols with anti-inflammatory properties | Q28192995 | ||
Mammalian MAP kinase signalling cascades | Q28204140 | ||
Heme oxygenase-1: the "emerging molecule" has arrived | Q28207978 | ||
Aspirin protects striatal dopaminergic neurons from neurotoxin-induced degeneration: an in vivo microdialysis study | Q28218248 | ||
Role of mitogen-activated protein kinase kinase 4 in cancer | Q28301942 | ||
alpha-Synuclein produces a long-lasting increase in neurotransmitter release | Q28510893 | ||
Mitochondrial free radical generation, oxidative stress, and aging | Q29614202 | ||
Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes | Q29617606 | ||
Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms | Q31967393 | ||
Well-water consumption and Parkinson's disease in rural California | Q33563011 | ||
Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease | Q33625539 | ||
Synucleins in synaptic plasticity and neurodegenerative disorders | Q33734797 | ||
Exercise protects against MPTP-induced neurotoxicity in mice. | Q33907587 | ||
Flavonoids as antioxidants | Q33912189 | ||
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease | Q33951094 | ||
Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease | Q33952130 | ||
Physical activities and future risk of Parkinson disease | Q34054934 | ||
Bioconjugates of curcumin display improved protection against glutathione depletion mediated oxidative stress in a dopaminergic neuronal cell line: Implications for Parkinson's disease | Q34103751 | ||
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS) | Q34681297 | ||
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet. | Q34859478 | ||
Free radicals in Parkinson's disease | Q34957112 | ||
Neuroprotective and neurorestorative strategies for Parkinson's disease | Q34982296 | ||
Unfolding the role of protein misfolding in neurodegenerative diseases | Q35038274 | ||
Apoptosis and Parkinson's disease | Q35092238 | ||
Disease model: Parkinson's disease. | Q35203031 | ||
The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins? | Q35206992 | ||
IGF-I receptor signaling pathway is involved in the neuroprotective effect of genistein in the neuroblastoma SK-N-SH cells. | Q39415715 | ||
Anticancer effect and apoptosis induction by quercetin in the human lung cancer cell line A-549. | Q39421924 | ||
The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties | Q39624081 | ||
Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease | Q39686152 | ||
Role of oxidation-triggered activation of JNK and p38 MAPK in black tea polyphenols induced apoptotic death of A375 cells | Q39826249 | ||
The prevalence of Parkinson's disease in a rural area of North-East England. | Q39943958 | ||
Apigenin inhibits the production of NO and PGE2 in microglia and inhibits neuronal cell death in a middle cerebral artery occlusion-induced focal ischemia mice model | Q40044970 | ||
A novel approach of proteomics and transcriptomics to study the mechanism of action of the antioxidant-iron chelator green tea polyphenol (-)-epigallocatechin-3-gallate | Q40104979 | ||
Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia. | Q40371518 | ||
The soy isoflavone, genistein, protects human cortical neuronal cells from oxidative stress | Q40529609 | ||
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death | Q40732702 | ||
Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death | Q40832650 | ||
Antioxidative action of flavonoids, quercetin and catechin, mediated by the activation of glutathione peroxidase | Q40921808 | ||
Modulation of Bcl-2 expression: a potential component of estrogen protection in NT2 neurons | Q41012212 | ||
Protective effects of flavonol isoquercitrin, against 6-hydroxy dopamine (6-OHDA)-induced toxicity in PC12 cells | Q41906540 | ||
Oxidative stress in Parkinson's disease | Q42051035 | ||
Quercetin glycosides induced neuroprotection by changes in the gene expression in a cellular model of Parkinson's disease | Q42704462 | ||
Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats | Q42713211 | ||
Neuroprotective effect of naringin, a dietary flavonoid against 3-nitropropionic acid-induced neuronal apoptosis | Q42726605 | ||
Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models. | Q42733707 | ||
Naringin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress induced by D-galactose in mice | Q43234972 | ||
Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbits | Q43807024 | ||
Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action | Q44023075 | ||
4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease | Q44108450 | ||
Indomethacin protects against neurodegeneration caused by MPTP intoxication in mice. | Q44154168 | ||
Glucosamine inhibits IL-1beta-induced NFkappaB activation in human osteoarthritic chondrocytes | Q44394411 | ||
Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activity | Q44643164 | ||
Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental stroke | Q45016492 | ||
The role of manganese superoxide dismutase in inflammation defense | Q35257552 | ||
Antioxidant Activity of Tea Polyphenols In Vivo: Evidence from Animal Studies | Q35547546 | ||
Regulation of apoptosis by Bcl‐2 family proteins | Q35574143 | ||
Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress | Q35753879 | ||
Occupational and environmental risk factors for Parkinson's disease | Q35791905 | ||
MPTP as a mitochondrial neurotoxic model of Parkinson's disease | Q35891901 | ||
Flavonoids in food and their health benefits | Q36023128 | ||
Parkinson's disease: from causes to mechanisms | Q36072236 | ||
Flavonoids and the aging brain. | Q36084519 | ||
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor | Q36086859 | ||
Oxidative stress and inflammation in Parkinson's disease: is there a causal link? | Q36115736 | ||
Role of cytokines in inflammatory process in Parkinson's disease. | Q36611576 | ||
Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondria | Q36661018 | ||
Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease | Q36896118 | ||
Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation? | Q37109892 | ||
Genistein inhibits TNF-α-induced endothelial inflammation through the protein kinase pathway A and improves vascular inflammation in C57BL/6 mice | Q37136678 | ||
Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease | Q37300999 | ||
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease | Q37419672 | ||
Parkinson's disease and mitochondrial complex I: a perspective on the Ndi1 therapy | Q37630973 | ||
Oxygen free radicals and Parkinson's disease | Q37693669 | ||
Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids | Q37936917 | ||
Free radicals, antioxidant enzymes, and carcinogenesis | Q37936921 | ||
Neuronal vulnerability in Parkinson's disease. | Q37968078 | ||
Natural polyphenols against neurodegenerative disorders: potentials and pitfalls | Q37984162 | ||
Aiding and abetting roles of NOX oxidases in cellular transformation | Q38037330 | ||
Regulation of Bax mitochondrial localization by Bcl-2 and Bcl-x(L): keep your friends close but your enemies closer | Q38051964 | ||
Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder? | Q38079791 | ||
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide | Q38318972 | ||
Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway | Q39044119 | ||
Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin | Q39051816 | ||
Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols. | Q39132165 | ||
Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity. | Q39152575 | ||
Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity. | Q39201466 | ||
Quercetin inhibits rhinovirus replication in vitro and in vivo | Q39371532 | ||
The lipid peroxidation by-product 4-hydroxy-2-nonenal (4-HNE) induces insulin resistance in skeletal muscle through both carbonyl and oxidative stress. | Q39384159 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P921 | main subject | Parkinson's disease | Q11085 |
2-phenylchromane flavonoid | Q222174 | ||
protective agent | Q50380088 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 314560 | |
P577 | publication date | 2015-10-20 | |
P1433 | published in | Oxidative medicine and cellular longevity | Q26840015 |
P1476 | title | Protective Mechanisms of Flavonoids in Parkinson's Disease | |
P478 | volume | 2015 |
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Q92136293 | Epalrestat improves motor symptoms by reducing oxidative stress and inflammation in the reserpine induced mouse model of Parkinson's disease |
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Q38764212 | Impact of Plant-Derived Flavonoids on Neurodegenerative Diseases. |
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