Protective Mechanisms of Flavonoids in Parkinson's Disease

scientific article published on 20 October 2015

Protective Mechanisms of Flavonoids in Parkinson's Disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1155/2015/314560
P932PMC publication ID4630416
P698PubMed publication ID26576219
P5875ResearchGate publication ID276849206

P50authorNagaraja HaleagraharaQ42087278
P2093author name stringAmmu Kutty Radhakrishnan
Kasthuri Bai Magalingam
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Flavonoids protect neuronal cells from oxidative stress by three distinct mechanismsQ31967393
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Disease model: Parkinson's disease.Q35203031
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IGF-I receptor signaling pathway is involved in the neuroprotective effect of genistein in the neuroblastoma SK-N-SH cells.Q39415715
Anticancer effect and apoptosis induction by quercetin in the human lung cancer cell line A-549.Q39421924
The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional propertiesQ39624081
Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's diseaseQ39686152
Role of oxidation-triggered activation of JNK and p38 MAPK in black tea polyphenols induced apoptotic death of A375 cellsQ39826249
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Apigenin inhibits the production of NO and PGE2 in microglia and inhibits neuronal cell death in a middle cerebral artery occlusion-induced focal ischemia mice modelQ40044970
A novel approach of proteomics and transcriptomics to study the mechanism of action of the antioxidant-iron chelator green tea polyphenol (-)-epigallocatechin-3-gallateQ40104979
Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia.Q40371518
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Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and deathQ40832650
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Quercetin glycosides induced neuroprotection by changes in the gene expression in a cellular model of Parkinson's diseaseQ42704462
Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in ratsQ42713211
Neuroprotective effect of naringin, a dietary flavonoid against 3-nitropropionic acid-induced neuronal apoptosisQ42726605
Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models.Q42733707
Naringin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress induced by D-galactose in miceQ43234972
Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbitsQ43807024
Involvement of protein kinase C activation and cell survival/ cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective actionQ44023075
4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary diseaseQ44108450
Indomethacin protects against neurodegeneration caused by MPTP intoxication in mice.Q44154168
Glucosamine inhibits IL-1beta-induced NFkappaB activation in human osteoarthritic chondrocytesQ44394411
Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activityQ44643164
Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental strokeQ45016492
The role of manganese superoxide dismutase in inflammation defenseQ35257552
Antioxidant Activity of Tea Polyphenols In Vivo: Evidence from Animal StudiesQ35547546
Regulation of apoptosis by Bcl‐2 family proteinsQ35574143
Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stressQ35753879
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MPTP as a mitochondrial neurotoxic model of Parkinson's diseaseQ35891901
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Flavonoids and the aging brain.Q36084519
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitorQ36086859
Oxidative stress and inflammation in Parkinson's disease: is there a causal link?Q36115736
Role of cytokines in inflammatory process in Parkinson's disease.Q36611576
Glutathione binding to the Bcl-2 homology-3 domain groove: a molecular basis for Bcl-2 antioxidant function at mitochondriaQ36661018
Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's diseaseQ36896118
Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation?Q37109892
Genistein inhibits TNF-α-induced endothelial inflammation through the protein kinase pathway A and improves vascular inflammation in C57BL/6 miceQ37136678
Human interleukin-10 gene transfer is protective in a rat model of Parkinson's diseaseQ37300999
Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's diseaseQ37419672
Parkinson's disease and mitochondrial complex I: a perspective on the Ndi1 therapyQ37630973
Oxygen free radicals and Parkinson's diseaseQ37693669
Suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acidsQ37936917
Free radicals, antioxidant enzymes, and carcinogenesisQ37936921
Neuronal vulnerability in Parkinson's disease.Q37968078
Natural polyphenols against neurodegenerative disorders: potentials and pitfallsQ37984162
Aiding and abetting roles of NOX oxidases in cellular transformationQ38037330
Regulation of Bax mitochondrial localization by Bcl-2 and Bcl-x(L): keep your friends close but your enemies closerQ38051964
Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder?Q38079791
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharideQ38318972
Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathwayQ39044119
Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigeninQ39051816
Mitochondrial membrane permeabilisation by amyloid aggregates and protection by polyphenols.Q39132165
Rutin, a bioflavonoid antioxidant protects rat pheochromocytoma (PC-12) cells against 6-hydroxydopamine (6-OHDA)-induced neurotoxicity.Q39152575
Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity.Q39201466
Quercetin inhibits rhinovirus replication in vitro and in vivoQ39371532
The lipid peroxidation by-product 4-hydroxy-2-nonenal (4-HNE) induces insulin resistance in skeletal muscle through both carbonyl and oxidative stress.Q39384159
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectParkinson's diseaseQ11085
2-phenylchromane flavonoidQ222174
protective agentQ50380088
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)314560
P577publication date2015-10-20
P1433published inOxidative medicine and cellular longevityQ26840015
P1476titleProtective Mechanisms of Flavonoids in Parkinson's Disease
P478volume2015

Reverse relations

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