| P50 | author | Nicholas Athanasou | Q91273304 |
| P2093 | author name string | D J Mahoney | |
| | A Sabokbar | |
| | F Hemingway | |
| P2860 | cites work | BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth | Q22009942 |
| | The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells | Q22254033 |
| | LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator | Q24308657 |
| | Role of the A20-TRAF6 axis in lipopolysaccharide-mediated osteoclastogenesis | Q24311417 |
| | Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation | Q24311588 |
| | APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth | Q24315058 |
| | Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1 | Q24323286 |
| | Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6 | Q24563585 |
| | LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer | Q24564377 |
| | RANK is essential for osteoclast and lymph node development | Q24598872 |
| | osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification | Q24603266 |
| | The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature | Q24647037 |
| | Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL | Q24682139 |
| | Osteoclasts: what do they do and how do they do it? | Q24683898 |
| | Pathobiology of Paget's Disease of Bone | Q26824476 |
| | APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death | Q28137894 |
| | Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival | Q28142897 |
| | Constitutive expression of LIGHT on T cells leads to lymphocyte activation, inflammation, and tissue destruction | Q28206179 |
| | RANKL-RANK signaling in osteoclastogenesis and bone disease | Q28287091 |
| | Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family | Q28295196 |
| | The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1 | Q28299663 |
| | Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects | Q28505493 |
| | SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts | Q28510858 |
| | TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling | Q28513445 |
| | OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 |
| | Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death | Q28609905 |
| | Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice | Q29547898 |
| | Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway | Q33228319 |
| | Biological activities and clinical application of M-CSF. | Q33502818 |
| | Regulation and regulatory activities of transforming growth factor beta | Q33592508 |
| | Osteoprotegerin ligand and osteoprotegerin: novel implications for osteoclast biology and bone metabolism | Q33726838 |
| | Effect of osteoprotegerin and osteoprotegerin ligand on osteoclast formation by arthroplasty membrane derived macrophages | Q33885983 |
| | Polymorphic variants of LIGHT (TNF superfamily-14) alter receptor avidity and bioavailability | Q34065607 |
| | Minireview: the OPG/RANKL/RANK system | Q34102256 |
| | The human osteoclast precursor circulates in the monocyte fraction | Q34392302 |
| | Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human | Q34503355 |
| | Transforming growth factor beta inhibits bone resorption in fetal rat long bone cultures | Q34560491 |
| | Adrenergic regulation of bone metabolism: possible involvement of sympathetic innervation of osteoblastic and osteoclastic cells | Q34803977 |
| | Functions of AP1 (Fos/Jun) in bone development | Q34963037 |
| | LIGHT-HVEM signaling and the regulation of T cell-mediated immunity | Q35145636 |
| | LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease. | Q35149611 |
| | Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone | Q35595884 |
| | Lymphotoxin and LIGHT signaling pathways and target genes | Q35951798 |
| | Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival | Q36370261 |
| | TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. | Q36404187 |
| | Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma | Q36609462 |
| | Malignant melanoma and bone resorption | Q36614173 |
| | Rheumatoid and pyrophosphate arthritis synovial fibroblasts induce osteoclastogenesis independently of RANKL, TNF and IL-6. | Q36670711 |
| | Cellular mechanisms of multiple myeloma bone disease | Q36925346 |
| | RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism | Q37108966 |
| | Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene | Q37265676 |
| | Evidence that cytokines play a role in rheumatoid arthritis | Q37316594 |
| | Transforming growth factor beta 1 induces CXCL16 and leukemia inhibitory factor expression in osteoclasts to modulate migration of osteoblast progenitors. | Q37354476 |
| | NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism | Q37363042 |
| | Canonical and non-canonical pathways of osteoclast formation | Q37364619 |
| | TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand | Q37413745 |
| | IL-23 is critical for induction of arthritis, osteoclast formation, and maintenance of bone mass. | Q37497970 |
| | The osteoclast--what's new? | Q37918962 |
| | Alternative pathways of osteoclastogenesis in inflammatory arthritis | Q38271156 |
| | Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin | Q39116155 |
| | Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model | Q40073713 |
| | The source of APRIL up-regulation in human solid tumor lesions. | Q40263657 |
| | Proinflammatory effects of LIGHT through HVEM and LTbetaR interactions in cultured human umbilical vein endothelial cells | Q40416895 |
| | Fra-1 replaces c-Fos-dependent functions in mice | Q40445308 |
| | Decoy receptor 3 (DcR3) induces osteoclast formation from monocyte/macrophage lineage precursor cells | Q40582077 |
| | Transforming growth factor-beta induces osteoclast formation in the absence of RANKL. | Q40594156 |
| | TRAF5 functions in both RANKL- and TNFalpha-induced osteoclastogenesis | Q40666297 |
| | Transforming growth factor-beta gene family members and bone | Q40739760 |
| | Vitamin D(3) augments osteoclastogenesis via vitamin D-responsive element of mouse RANKL gene promoter | Q40757897 |
| | IL-1 mediates TNF-induced osteoclastogenesis | Q40909592 |
| | Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells | Q40927574 |
| | Human osteoclasts derive from CD14-positive monocytes | Q40936101 |
| | The insulin-like growth factor system and the coupling of formation to resorption | Q40957426 |
| | Transforming growth factor-beta stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cells | Q41004339 |
| | Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function | Q41391211 |
| | Osteoclast markers accumulate on cells developing from human peripheral blood mononuclear precursors | Q41608135 |
| | IL-6 is produced by osteoblasts and induces bone resorption | Q41714818 |
| | Crosstalk among IL-23 and DNAX activating protein of 12 kDa-dependent pathways promotes osteoclastogenesis | Q41752189 |
| | Tumor necrosis factor-alpha and its receptors, p55 and p75, in gingiva of adult periodontitis | Q42508467 |
| | The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome | Q43050637 |
| | Insulin-like growth factor-I supports formation and activation of osteoclasts | Q43458688 |
| | TGF-beta isoform and receptor expression in giant cell tumor and giant cell lesions of bone | Q43632670 |
| | Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouse | Q43681246 |
| | IGF2 modulates the microenvironment for osteoclastogenesis | Q44571146 |
| | Investigation of osteoclastogenic signalling of the RANKL substitute LIGHT. | Q44754181 |
| | Isolation of a novel insulin-like growth factor (IGF) binding protein from human bone: a potential candidate for fixing IGF-II in human bone | Q46149499 |
| | Role of IGF-I signaling in regulating osteoclastogenesis | Q46171428 |
| | The role of RANKL (TRANCE/TNFSF11), a tumor necrosis factor family member, in skeletal development: effects of gene knockout and transgenic rescue | Q46286533 |
| | NADPH oxidase activation is required for migration by LIGHT in human monocytes | Q46603608 |
| | RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II. | Q46628325 |
| | LIGHT induces cell proliferation and inflammatory responses of rheumatoid arthritis synovial fibroblasts via lymphotoxin beta receptor | Q46645020 |
| | Human interleukin-1-induced murine osteoclastogenesis is dependent on RANKL, but independent of TNF-alpha | Q47624693 |
| | Interleukin-8 stimulation of osteoclastogenesis and bone resorption is a mechanism for the increased osteolysis of metastatic bone disease. | Q47687944 |
| | A role for the lymphotoxin/LIGHT axis in the pathogenesis of murine collagen-induced arthritis | Q47817061 |
| | Update on the biologic effects of macrophage colony-stimulating factor. | Q47846474 |
| | Hypoxic stress enhances osteoclast differentiation via increasing IGF2 production by non-osteoclastic cells | Q47849526 |
| | Gene expression of monocyte chemoattractant protein-1 in giant cell tumors of bone osteoclastoma: possible involvement in CD68+ macrophage-like cell migration | Q47957048 |
| | Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells. 1975. | Q48940690 |
| | TRAF2 is essential for TNF-alpha-induced osteoclastogenesis. | Q50335956 |
| | Innervation of periosteum and bone by sympathetic vasoactive intestinal peptide-containing nerve fibers. | Q50909472 |
| | Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. | Q52192178 |
| | Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption. | Q52511692 |
| | Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism. | Q53941037 |
| | Two distinct cellular mechanisms of osteoclast formation and bone resorption in periprosthetic osteolysis. | Q53945794 |
| | The expression of mRNA for insulin-like growth factors and their receptor in giant cell tumors of human bone. | Q54154646 |
| | Does TNF have anti-osteoclastogenic actions? | Q54592893 |
| | Tumor Necrosis Factor α Regulatesαvβ5Integrin Expression by Osteoclast Precursorsin Vitro and in Vivo1 | Q58085549 |
| | RANKL-dependent and RANKL-independent mechanisms of macrophage-osteoclast differentiation in breast cancer | Q58211830 |
| | JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms | Q58326878 |
| | The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 |
| | Synovial fluid macrophages are capable of osteoclast formation and resorption | Q61703801 |
| | TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin | Q62078407 |
| | LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis | Q63253234 |
| | Insulin-like growth factors I and II are present in the skeletal tissues of ten vertebrates | Q67266453 |
| | Localization of tumor necrosis factor alpha in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis | Q68028260 |
| | Primary structure of human skeletal growth factor: homology with human insulin-like growth factor-II | Q68431796 |
| | Nerve growth factor in skeletal tissues of the embryonic chick | Q68858656 |
| | Short-term local injections of transforming growth factor-beta 1 decrease ovariectomy-stimulated osteoclastic resorption in vivo in rats | Q71773712 |
| | Osteoblasts and osteoclasts in adult human osteophyte tissue express the mRNAs for insulin-like growth factors I and II and the type 1 IGF receptor | Q72326655 |
| | Role of colony-stimulating factor-1 in bone metabolism | Q72809748 |
| | Rapid proliferation of calcitonin gene-related peptide-immunoreactive nerves during healing of rat tibial fracture suggests neural involvement in bone growth and remodelling | Q72857285 |
| | Evidence for a dense and intimate innervation of the bone tissue, including glutamate-containing fibers | Q73262130 |
| | Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts | Q73441763 |
| | LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response | Q73644490 |
| | Expression of osteoclast differentiation signals by stromal elements of giant cell tumors | Q73711524 |
| | Expression of neurotrophins and their receptors (TRK) during fracture healing | Q73835346 |
| | Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone | Q73835736 |
| | Growth hormone stimulatory effects on osteoclastic resorption are partly mediated by insulin-like growth factor I: an in vitro study | Q74071843 |
| | Transforming growth factor-beta1 (TGF-beta) stimulates the osteoclast-forming potential of peripheral blood hematopoietic precursors in a lymphocyte-rich microenvironment | Q74095881 |
| | Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function | Q74244387 |
| | Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization | Q74742272 |
| | Proinflammatory cytokine (TNFalpha/IL-1alpha) induction of human osteoclast formation | Q74802758 |
| | Cellular and humoral mechanisms of osteoclast formation and bone resorption in Gorham-Stout disease | Q77358465 |
| | Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cells | Q77484251 |
| | Immunohistochemical localization of nerve growth factor in fractured and unfractured rat bone | Q77497919 |
| | TNFalpha potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL | Q77679093 |
| | Locally applied nerve growth factor enhances bone consolidation in a rabbit model of mandibular distraction osteogenesis | Q79139219 |
| | LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes | Q80060014 |
| | The TNF superfamily member LIGHT contributes to survival and activation of synovial fibroblasts in rheumatoid arthritis | Q80140388 |
| | BAFF overexpression is associated with autoantibody production in autoimmune diseases | Q80367249 |
| | Murine osteoclast formation and function: differential regulation by humoral agents | Q82129423 |
| | The interaction of monocytes with rheumatoid synovial cells is a key step in LIGHT-mediated inflammatory bone destruction | Q82661844 |
| | Depth and volume of resorption induced by osteoclasts generated in the presence of RANKL, TNF-alpha/IL-1 or LIGHT | Q82976484 |
| | BAFF and APRIL as osteoclast-derived survival factors for myeloma cells: a rationale for TACI-Fc treatment in patients with multiple myeloma | Q83159481 |
| | A role for HVEM, but not lymphotoxin-beta receptor, in LIGHT-induced tumor cell death and chemokine production | Q84454564 |
| P433 | issue | 1 | |
| P304 | page(s) | 16-26 | |
| P577 | publication date | 2015-11-17 | |
| P1433 | published in | Clinical Reviews in Allergy & Immunology | Q1932354 |
| P1476 | title | Non-Canonical (RANKL-Independent) Pathways of Osteoclast Differentiation and Their Role in Musculoskeletal Diseases | |
| P478 | volume | 51 | |