Rosuvastatin improves endothelial function in db/db mice: role of angiotensin II type 1 receptors and oxidative stress.

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Rosuvastatin improves endothelial function in db/db mice: role of angiotensin II type 1 receptors and oxidative stress. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1476-5381.2011.01416.X
P932PMC publication ID3188899
P698PubMed publication ID21486274
P5875ResearchGate publication ID51044948

P50authorYu HuangQ56528909
Wing Tak WongQ56988879
Xiaoqiang YaoQ57009857
Vivian Wing Yan LeeQ81457412
P2093author name stringY Lu
Z Y Chen
A Xu
L M Liu
X Y Tian
C W Lau
P2860cites workAntioxidant and antiplatelet effects of rosuvastatin in a hamster model of prediabetes.Q51801075
HMG-CoA Reductase Inhibitors Decrease Angiotensin II–Induced Vascular FibrosisQ61854913
Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic menQ73205391
Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin-induced diabetes mellitusQ79706677
Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic miceQ79948551
Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db miceQ80477528
The central role of adenosine in statin-induced ERK1/2, Akt, and eNOS phosphorylationQ80580061
Simvastatin preserves coronary endothelial function in hypercholesterolemia in the absence of lipid loweringQ31807283
Endothelial dysfunction in diabetes.Q33959485
Behavioral science research in diabetes: lifestyle changes related to obesity, eating behavior, and physical activity.Q34149216
Therapeutic levels of the hydroxmethylglutaryl-coenzyme A reductase inhibitor lovastatin activate ras signaling via phospholipase D2.Q34742771
Role of C-reactive protein in the assessment of cardiovascular riskQ35042927
The roles of hyperglycaemia and oxidative stress in the rise and collapse of the natural protective mechanism against vascular endothelial cell dysfunction in diabetesQ37044976
Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatmentQ37196829
Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities.Q37245109
Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signallingQ37380419
Endothelial dysfunction: the common consequence in diabetes and hypertension.Q37737686
Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase.Q39878461
Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic miceQ43171566
HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen speciesQ43641701
Pitavastatin enhanced BMP-2 and osteocalcin expression by inhibition of Rho-associated kinase in human osteoblastsQ43735838
Effects of rosuvastatin on nitric oxide-dependent function in aorta and corpus cavernosum of diabetic mice: relationship to cholesterol biosynthesis pathway inhibition and lipid loweringQ44564063
Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose: results from the LIPID trialQ44599698
Oxidative stress in the pathogenesis of thoracic aortic aneurysm: protective role of statin and angiotensin II type 1 receptor blockerQ44614425
Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathyQ45012594
Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection.Q45037051
Rosuvastatin attenuates monocyte-endothelial cell interactions and vascular free radical production in hypercholesterolemic miceQ45234516
Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levelsQ45280966
Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice.Q45954983
Effects of statins on vascular endothelial function in hypercholesterolemic patients with type 2 diabetes mellitus: fluvastatin vs. rosuvastatinQ46143681
Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitorsQ46211676
Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockadeQ46443790
Participation of K+ channels in the endothelium-dependent and endothelium-independent components of the relaxant effect of rosuvastatin in rat aortic ringsQ46477436
Effect of rosuvastatin on capillary filtration of albumin and blood pressure in rats with streptozotocin-induced diabetesQ46649543
Effects of rosuvastatin on endothelial function in patients with familial combined hyperlipidaemia (FCH).Q46730270
Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide productionQ46801152
The protective effect of rosuvastatin in human umbilical endothelial cells exposed to constant or intermittent high glucoseQ46811479
Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice.Q46862910
Improvement in endothelium dysfunction in diabetics treated with statins: a randomized comparison of atorvastatin 20 mg versus rosuvastatin 10 mg.Q46879881
Reduced coronary events in simvastatin-treated patients with coronary heart disease and diabetes or impaired fasting glucose levels: subgroup analyses in the Scandinavian Simvastatin Survival Study.Q51559365
Cardiovascular events and their reduction with pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: subgroup analyses in the cholesterol and recurrent events (CARE) trial. The Care InvestigaQ51566349
P433issue2b
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
P304page(s)598-606
P577publication date2011-09-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleRosuvastatin improves endothelial function in db/db mice: role of angiotensin II type 1 receptors and oxidative stress
P478volume164

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cites work (P2860)
Q36996652Activation of renin-angiotensin system is involved in dyslipidemia-mediated renal injuries in apolipoprotein E knockout mice and HK-2 cells
Q46843512Anti-oxidative stress effect of loading-dose rosuvastatin prior to percutaneous coronary intervention in patients with acute coronary syndrome: a prospective randomized controlled clinical trial
Q36994190Astaxanthin attenuates the apoptosis of retinal ganglion cells in db/db mice by inhibition of oxidative stress
Q38208727Benefit-risk assessment of rosuvastatin in the treatment of atherosclerosis and related diseases.
Q26991619Biochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular system
Q35705401Boldine Ameliorates Vascular Oxidative Stress and Endothelial Dysfunction: Therapeutic Implication for Hypertension and Diabetes
Q41824130Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II-mediated BMP4-oxidative stress cascade
Q55405814Comparison of Pulmonary and Systemic NO- and PGI2-Dependent Endothelial Function in Diabetic Mice.
Q41652967Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis
Q54989042Effect of rosuvastatin on the expression of candidate gene GALNT3 in atherosclerosis.
Q37707720Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells.
Q51317623PTEN upregulation may explain the development of insulin resistance and type 2 diabetes with high dose statins.
Q85427908Possible involvement of PPARγ-associated eNOS signaling activation in rosuvastatin-mediated prevention of nicotine-induced experimental vascular endothelial abnormalities
Q47377607Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering
Q47835623Rosuvastatin inhibits high glucose-stimulated upregulation of VCAM-1 via the MAPK-signalling pathway in endothelial cells
Q90605122Rosuvastatin reverses hypertension-induced changes in the aorta structure and endothelium-dependent relaxation in rats through suppression of apoptosis and inflammation
Q47903414Saxagliptin prevents vascular remodeling and oxidative stress in db/db mice. Role of endothelial nitric oxide synthase uncoupling and cyclooxygenase
Q36672866The endothelium in diabetes: its role in insulin access and diabetic complications
Q28076034Treating the host response to emerging virus diseases: lessons learned from sepsis, pneumonia, influenza and Ebola
Q46819734Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways

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