| scholarly article | Q13442814 |
| P356 | DOI | 10.2217/NMT.15.50 |
| P698 | PubMed publication ID | 26619755 |
| P50 | author | Steven Petratos | Q63700525 |
| P2093 | author name string | Jae Young Lee | |
| Melissa Biemond | |||
| P2860 | cites work | Iron is a sensitive biomarker for inflammation in multiple sclerosis lesions | Q21090792 |
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| Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth | Q28204972 | ||
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| Neurofascins are required to establish axonal domains for saltatory conduction | Q28512452 | ||
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| Determinants of brain iron in multiple sclerosis: a quantitative 3T MRI study | Q48859916 | ||
| Granule-derived granzyme B mediates the vulnerability of human neurons to T cell-induced neurotoxicity | Q48868377 | ||
| Iron efflux from oligodendrocytes is differentially regulated in gray and white matter. | Q48898990 | ||
| Inflammation stimulates remyelination in areas of chronic demyelination | Q49070234 | ||
| Oligoclonal immunoglobulins and plasma cells in spinal fluid of patients with multiple sclerosis | Q50417372 | ||
| Alterations of juxtaparanodal domains in two rodent models of CNS demyelination. | Q50856877 | ||
| Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis. | Q51027456 | ||
| Functions of Nogo proteins and their receptors in the nervous system. | Q51896522 | ||
| Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis. | Q52047001 | ||
| Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve. | Q52134357 | ||
| In vivo effect of sera from animals with chronic relapsing experimental allergic encephalomyelitis on central and peripheral myelin. | Q52506094 | ||
| Contact with central nervous system myelin inhibits oligodendrocyte progenitor maturation. | Q54374042 | ||
| Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis. | Q54676875 | ||
| Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. | Q39266450 | ||
| Phagocytosis of neuronal debris by microglia is associated with neuronal damage in multiple sclerosis | Q39429415 | ||
| Glial and neuronal isoforms of Neurofascin have distinct roles in the assembly of nodes of Ranvier in the central nervous system | Q39644189 | ||
| Increased CD8+ cytotoxic T cell responses to myelin basic protein in multiple sclerosis | Q40569666 | ||
| Latent virus infection upregulates CD40 expression facilitating enhanced autoimmunity in a model of multiple sclerosis | Q41007071 | ||
| Axonally derived neuregulin-1 is required for remyelination and regeneration after nerve injury in adulthood. | Q41819452 | ||
| Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients | Q41826954 | ||
| Intracerebral human regulatory T cells: analysis of CD4+ CD25+ FOXP3+ T cells in brain lesions and cerebrospinal fluid of multiple sclerosis patients. | Q41869890 | ||
| Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes | Q41959017 | ||
| Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response. | Q42251580 | ||
| In vivo imaging of partially reversible th17 cell-induced neuronal dysfunction in the course of encephalomyelitis | Q42876667 | ||
| Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination. | Q43738357 | ||
| Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate | Q43965259 | ||
| Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial | Q44264108 | ||
| The role of CD8+ T cells and their local interaction with CD4+ T cells in myelin oligodendrocyte glycoprotein35-55-induced experimental autoimmune encephalomyelitis | Q44411501 | ||
| Altered expression patterns of group I and II metabotropic glutamate receptors in multiple sclerosis | Q44477073 | ||
| Epidemiology of multiple sclerosis. Does this really point toward an etiology? Lectio Doctoralis | Q44689572 | ||
| Direct impact of T cells on neurons revealed by two-photon microscopy in living brain tissue. | Q44795497 | ||
| Multiple sclerosis: validation of MR imaging for quantification and detection of iron. | Q45138808 | ||
| Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T. | Q46083107 | ||
| Neurogenesis and neuroprotection induced by peripheral immunomodulatory treatment of experimental autoimmune encephalomyelitis. | Q46691355 | ||
| Detection of ectopic B-cell follicles with germinal centers in the meninges of patients with secondary progressive multiple sclerosis. | Q47357498 | ||
| Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis. | Q48025137 | ||
| Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes | Q48099707 | ||
| Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter | Q48105976 | ||
| Cross-recognition of a myelin peptide by CD8+ T cells in the CNS is not sufficient to promote neuronal damage. | Q48211678 | ||
| Multiple sclerosis. Pathology of recurrent lesions | Q48269367 | ||
| Identification of glial cell proliferation in early multiple sclerosis lesions | Q48375316 | ||
| Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death | Q48380024 | ||
| Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis | Q48397010 | ||
| Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis. | Q48406120 | ||
| Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study | Q48408024 | ||
| Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time | Q48483179 | ||
| Benefit of interferon beta-1a on MSFC progression in secondary progressive MS. | Q48489376 | ||
| Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis | Q48501398 | ||
| Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity | Q48510916 | ||
| Neurotransmitters in cerebrospinal fluid reflect pathological activity | Q48534847 | ||
| Myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas- and Fas ligand-deficient lpr and gld mice | Q48535553 | ||
| Late motor decline after accomplished remyelination: impact for progressive multiple sclerosis | Q48639246 | ||
| The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion | Q48646930 | ||
| Impairment of learning and memory in TAG-1 deficient mice associated with shorter CNS internodes and disrupted juxtaparanodes | Q28588262 | ||
| LINGO-1 negatively regulates myelination by oligodendrocytes | Q28588853 | ||
| NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans | Q28594524 | ||
| Axonal transection in the lesions of multiple sclerosis | Q29615585 | ||
| A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis | Q29616119 | ||
| Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis | Q29620481 | ||
| Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial | Q30053056 | ||
| Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis | Q30480387 | ||
| Inefficient clearance of myelin debris by microglia impairs remyelinating processes | Q30636334 | ||
| Expression of major histocompatibility complex class I molecules on the different cell types in multiple sclerosis lesions. | Q30758003 | ||
| Changes in the expression and localization of the paranodal protein Caspr on axons in chronic multiple sclerosis | Q31146100 | ||
| Axon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/Paranodin | Q31923923 | ||
| Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice | Q33597044 | ||
| Novel forms of neurofascin 155 in the central nervous system: alterations in paranodal disruption models and multiple sclerosis | Q33656323 | ||
| Complement activation in multiple sclerosis plaques: an immunohistochemical analysis | Q33722349 | ||
| Spatiotemporal ablation of myelinating glia-specific neurofascin (Nfasc NF155) in mice reveals gradual loss of paranodal axoglial junctions and concomitant disorganization of axonal domains. | Q33722493 | ||
| The Nogo-Nogo receptor pathway limits a spectrum of adult CNS axonal growth | Q33767284 | ||
| Rituximab therapy reduces organ-specific T cell responses and ameliorates experimental autoimmune encephalomyelitis | Q33832088 | ||
| Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells | Q33930062 | ||
| MRI assessment of iron deposition in multiple sclerosis | Q33941442 | ||
| Oligodendroglia metabolically support axons and contribute to neurodegeneration. | Q34032818 | ||
| Silencing Nogo-A promotes functional recovery in demyelinating disease | Q34089956 | ||
| Multiple sclerosis: distribution of inflammatory cells in newly forming lesions | Q34089994 | ||
| Atlas of Multiple Sclerosis 2013: A growing global problem with widespread inequity | Q34170954 | ||
| The immunomodulator glatiramer acetate augments the expression of neurotrophic factors in brains of experimental autoimmune encephalomyelitis mice | Q34245104 | ||
| Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH. | Q34253953 | ||
| Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones | Q34255679 | ||
| Mechanisms of axonal injury: internodal nanocomplexes and calcium deregulation | Q34292220 | ||
| Excitatory amino acids as a final common pathway for neurologic disorders. | Q34321926 | ||
| Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. | Q34324660 | ||
| Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG) | Q34375520 | ||
| Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse | Q34384488 | ||
| Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel | Q34405882 | ||
| Iron and neurodegeneration in the multiple sclerosis brain | Q34470577 | ||
| Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation | Q34683399 | ||
| Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases. | Q34710256 | ||
| Multiple sclerosis: an immune or neurodegenerative disorder? | Q34786872 | ||
| Memantine induces reversible neurologic impairment in patients with MS. | Q34906988 | ||
| Immunoglobulins and complement in postmortem multiple sclerosis tissue | Q34937786 | ||
| Recovery from chronic spinal cord contusion after Nogo receptor intervention | Q35616151 | ||
| Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions | Q35745974 | ||
| Absence of perforin expression confers axonal protection despite demyelination. | Q35762252 | ||
| Mammalian peroxisomes and reactive oxygen species | Q35829813 | ||
| Peroxisomes, lipid metabolism, and peroxisomal disorders | Q35908942 | ||
| K+ channel alterations in the progression of experimental autoimmune encephalomyelitis | Q36007543 | ||
| Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis | Q36031613 | ||
| Neurofascin as a novel target for autoantibody-mediated axonal injury | Q36228999 | ||
| Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain | Q36229219 | ||
| Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction | Q36368672 | ||
| A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis | Q36376307 | ||
| Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis. | Q36494558 | ||
| Lymphocytes with cytotoxic activity induce rapid microtubule axonal destabilization independently and before signs of neuronal death | Q36590210 | ||
| Multiple sclerosis: brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood | Q36602220 | ||
| Abnormal NMDA receptor function exacerbates experimental autoimmune encephalomyelitis | Q36610373 | ||
| Axonal conduction and injury in multiple sclerosis: the role of sodium channels | Q36657811 | ||
| Limiting multiple sclerosis related axonopathy by blocking Nogo receptor and CRMP-2 phosphorylation | Q36661334 | ||
| Increased concentrations of glutamate and glutamine in normal-appearing white matter of patients with multiple sclerosis and normal MR imaging brain scans | Q36774758 | ||
| Multiple sclerosis: a complicated picture of autoimmunity. | Q36915907 | ||
| The origin and application of experimental autoimmune encephalomyelitis | Q36961600 | ||
| Axon-glial signaling and the glial support of axon function | Q37193060 | ||
| Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals | Q37208572 | ||
| Axons are injured by antigen-specific CD8(+) T cells through a MHC class I- and granzyme B-dependent mechanism | Q37210942 | ||
| Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis | Q37398059 | ||
| Demyelinated axons and motor function are protected by genetic deletion of perforin in a mouse model of multiple sclerosis | Q37399033 | ||
| GPI-anchored proteins at the node of Ranvier. | Q37585680 | ||
| Myelination and support of axonal integrity by glia | Q37808620 | ||
| Changes at the nodal and perinodal axonal domains: a basis for multiple sclerosis pathology? | Q37973165 | ||
| Multiple sclerosis: does Nogo play a role? | Q38082999 | ||
| The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment. | Q38186206 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | multiple sclerosis | Q8277 |
| P304 | page(s) | 527-548 | |
| P577 | publication date | 2015-12-01 | |
| P1433 | published in | Neurodegenerative disease management | Q27020361 |
| P1476 | title | Axonal degeneration in multiple sclerosis: defining therapeutic targets by identifying the causes of pathology | |
| P478 | volume | 5 |
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