Biosynthesis of Diterpenoids in Tripterygium Adventitious Root Cultures

scientific article

Biosynthesis of Diterpenoids in Tripterygium Adventitious Root Cultures is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1104/PP.17.00659
P932PMC publication ID5580761
P698PubMed publication ID28751314

P50authorReuben J. PetersQ40370805
Michael HartmannQ43054571
Amber N ParrishQ57030548
Narayanan SrividyaQ60034626
Mark LangeQ88799391
P2093author name stringMeimei Xu
Justin T Fischedick
Iris Lange
Fainmarinat S Inabuy
P2860cites workLoblolly pine abietadienol/abietadienal oxidase PtAO (CYP720B1) is a multifunctional, multisubstrate cytochrome P450 monooxygenaseQ24528906
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To gibberellins and beyond! Surveying the evolution of (di)terpenoid metabolismQ27014087
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The family of terpene synthases in plants: a mid-size family of genes for specialized metabolism that is highly diversified throughout the kingdomQ34173830
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Functional analysis of (4S)-limonene synthase mutants reveals determinants of catalytic outcome in a model monoterpene synthaseQ35212562
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Extracts of Tripterygium wilfordii Hook F in the Treatment of Rheumatoid Arthritis: A Systemic Review and Meta-Analysis of Randomised Controlled TrialsQ36896228
Meta-Analysis of Tripterygium Wilfordii Hook F in the Immunosuppressive Treatment of IgA NephropathyQ37798651
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Tripterygium preparations for the treatment of CKD: a systematic review and meta-analysisQ38105764
Targets and molecular mechanisms of triptolide in cancer therapyQ38268610
Expanding the Landscape of Diterpene Structural Diversity through Stereochemically Controlled Combinatorial BiosynthesisQ38495747
Integrative Approaches for the Identification and Localization of Specialized Metabolites in Tripterygium Roots.Q39173084
Synthesis and biological evaluation of dehydroabietic acid derivatives.Q39778597
Kaurane and abietane diterpenoids from Tripterygium doianum (Celastraceae).Q40530979
A modular approach for facile biosynthesis of labdane-related diterpenesQ41878218
Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the LamiaceaeQ41950927
Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii.Q42057829
Interaction with the small subunit of geranyl diphosphate synthase modifies the chain length specificity of geranylgeranyl diphosphate synthase to produce geranyl diphosphateQ43815799
Tripterygium wilfordii Hook. f. - how a traditional Taiwanese medicinal plant found its way to the WestQ44306703
Modularity of Conifer Diterpene Resin Acid Biosynthesis: P450 Enzymes of Different CYP720B Clades Use Alternative Substrates and Converge on the Same Products.Q46586219
Chemical comparison of Tripterygium wilfordii and Tripterygium hypoglaucum based on quantitative analysis and chemometrics methodsQ46910843
Immunosuppressive diterpenoids from Tripterygium wilfordiiQ47694350
The terpene synthase gene family in Tripterygium wilfordii harbors a labdane-type diterpene synthase among the monoterpene synthase TPS-b subfamily.Q47852658
The GA2 locus of Arabidopsis thaliana encodes ent-kaurene synthase of gibberellin biosynthesisQ48038021
Evolution of diterpene metabolism: Sitka spruce CYP720B4 catalyzes multiple oxidations in resin acid biosynthesis of conifer defense against insectsQ48055272
Gene discovery of modular diterpene metabolism in nonmodel systems.Q51046887
Terpenoids in transformed root culture of Tripterygium wilfordiiQ77181142
Anti-inflammatory oleanane triterpenes from Tripterygium wilfordii cell suspension cultures by fungal elicitationQ86657282
Simultaneous quantification of 18 bioactive constituents in Tripterygium wilfordii using liquid chromatography-electrospray ionization-mass spectrometryQ86842583
Elicitation and in situ adsorption enhanced secondary metabolites production of Tripterygium wilfordii Hook. f. adventitious root fragment liquid cultures in shake flask and a modified bubble column bioreactorQ87250583
Establishment of Tripterygium wilfordii Hook. f. Hairy root culture and optimization of its culture conditions for the production of triptolide and wilforineQ87483807
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)92-103
P577publication date2017-07-27
P1433published inPlant PhysiologyQ3906288
P1476titleBiosynthesis of Diterpenoids in Tripterygium Adventitious Root Cultures
P478volume175

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cites work (P2860)
Q46384619Antimicrobial Abietane-Type Diterpenoids from Plectranthus punctatus.
Q91730681Engineering chimeric diterpene synthases and isoprenoid biosynthetic pathways enables high-level production of miltiradiene in yeast
Q89810210Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis
Q47685656Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii
Q89944937Nerylneryl diphosphate is the precursor of serrulatane, viscidane and cembrane-type diterpenoids in Eremophila species
Q42657530Probing the Single Key Amino Acid Responsible for the Novel Catalytic Function of ent-Kaurene Oxidase Supported by NADPH-Cytochrome P450 Reductases in Tripterygium wilfordii
Q92183618Promiscuous terpene synthases from Prunella vulgaris highlight the importance of substrate and compartment switching in terpene synthase evolution

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