Opening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing

scientific article

Opening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/PD.5114
P932PMC publication ID5836985
P698PubMed publication ID28695688

P50authorMichael ParkerQ29643394
Ruth HornQ89722419
P2093author name stringRuth Horn
P2860cites workProcreative beneficence: why we should select the best childrenQ28203845
Letting the genome out of the bottle--will we get our wish?Q28264215
Ethical issues in consumer genome sequencing: Use of consumers' samples and dataQ28602462
ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencingQ29616235
Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research dataQ30881351
Prenatal whole genome sequencing: just because we can, should we?Q33959897
Return of genomic results to research participants: the floor, the ceiling, and the choices in betweenQ34000877
An exploration of genetic counselors' needs and experiences with prenatal chromosomal microarray testingQ34099702
Prenatal whole-genome sequencing--is the quest to know a fetus's future ethical?Q34398040
Promises, pitfalls and practicalities of prenatal whole exome sequencingQ34558273
Prenatal exome sequencing for fetuses with structural abnormalities: the next stepQ87662199
Evolving applications of microarray analysis in prenatal diagnosisQ35255522
Public perspectives on returning genetics and genomics research resultsQ35564757
Pregnancy Loss Following Amniocentesis or CVS Sampling-Time for a Reassessment of RiskQ35667154
Genetic information: a joint account?Q35838575
Noninvasive whole-genome sequencing of a human fetus.Q36048523
Parents' perceptions of the usefulness of chromosomal microarray analysis for children with autism spectrum disordersQ36068717
One-time general consent for research on biological samplesQ36412166
An old problem in a new age: Revisiting the clinical dilemma of misattributed paternityQ36699756
The best possible childQ37004931
Non-invasive prenatal testing for single gene disorders: exploring the ethicsQ37044362
Uptake, outcomes, and costs of implementing non-invasive prenatal testing for Down's syndrome into NHS maternity care: prospective cohort study in eight diverse maternity unitsQ37067727
Criteria for fairly allocating scarce health-care resources to genetic tests: which matter most?Q37397621
Genome sequencing: a systematic review of health economic evidenceQ37418013
Women's experiences receiving abnormal prenatal chromosomal microarray testing resultsQ37424832
Stakeholder views on returning research resultsQ38164857
Ethical issues raised by whole genome sequencingQ38210301
Managing the ethical challenges of next-generation sequencing in genomic medicineQ38239811
Prevalence and architecture of de novo mutations in developmental disordersQ38991782
The foundation of the child's right to an open futureQ39064683
The new genetics and informed consent: differentiating choice to preserve autonomyQ39411069
Prenatal whole-exome sequencing: parental attitudesQ40761599
An unwelcome side effect of direct-to-consumer personal genome testing: raiding the medical commonsQ42091906
Cell-free fetal DNA: the new tool in fetal medicineQ42393162
Revealing the results of whole-genome sequencing and whole-exome sequencing in research and clinical investigations: some ethical issuesQ45183763
The routine and the traumatic in prenatal genetic diagnosis: does clinical information inform patient decision-making?Q47291099
Imposing genetic diversityQ48037197
Advances in prenatal screening: the ethical dimension.Q48609420
An offer you can't refuse? Ethical implications of non-invasive prenatal diagnosisQ49161578
Family communication matters: the impact of telling relatives about unclassified variants and uninformative DNA-test results.Q51498901
The search for clarity in communicating research results to study participants.Q53132496
Content Analysis of Informed Consent for Whole Genome Sequencing Offered by Direct-to-Consumer Genetic Testing Companies.Q54465016
Generic Consent for Genetic ScreeningQ56894329
Presence of fetal DNA in maternal plasma and serumQ57075132
Return of results: not that complicated?Q57644037
Deploying whole genome sequencing in clinical practice and public health: meeting the challenge one bin at a timeQ57785176
Microarrays as a diagnostic tool in prenatal screening strategies: ethical reflectionQ58663048
Revealing false paternity: some ethical considerationsQ58669807
The disability rights critique of prenatal genetic testing. Reflections and RecommendationsQ73249140
Disability equality and prenatal testing: contradictory or compatible?Q79924672
P275copyright licenseCreative Commons AttributionQ6905323
P433issue1
P921main subjectresearch ethicsQ1132684
whole genome sequencingQ2068526
exome sequencingQ5420592
Maternal Serum Screening TestQ73040089
P304page(s)20-25
P577publication date2017-08-07
2018-01-01
P1433published inPrenatal DiagnosisQ15760059
P1476titleOpening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing
P478volume38

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cites work (P2860)
Q48280857Amniocentesis is still the best option for advanced genomic testing in case of fetal malformations
Q92475712Case report: targeted whole exome sequencing enables the first prenatal diagnosis of the lethal skeletal dysplasia Osteocraniostenosis
Q56517284Ethical and Counseling Challenges in Prenatal Exome Sequencing
Q92659362From diagnostic yield to clinical impact: a pilot study on the implementation of prenatal exome sequencing in routine care
Q89303078Genetic Counselors' Perspectives About Cell-Free DNA: Experiences, Challenges, and Expectations for Obstetricians
Q57643473Health professionals' and researchers' perspectives on prenatal whole genome and exome sequencing: 'We can't shut the door now, the genie's out, we need to refine it'
Q49339134Paediatric genomics: diagnosing rare disease in children
Q64108553Prenatal exome sequencing analysis in fetal structural anomalies detected by ultrasonography (PAGE): a cohort study
Q34558273Promises, pitfalls and practicalities of prenatal whole exome sequencing
Q88212766Rapid prenatal diagnosis using targeted exome sequencing: a cohort study to assess feasibility and potential impact on prenatal counseling and pregnancy management
Q50083885Whole Exome Sequencing: Applications in Prenatal Genetics

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