review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1146/ANNUREV-BIOCHEM-061516-044617 |
P698 | PubMed publication ID | 28654325 |
P50 | author | Ada Yonath | Q7426 |
Donna Matzov | Q54687679 | ||
Anat Bashan | Q28027621 | ||
P2860 | cites work | Ribosomal protection proteins and their mechanism of tetracycline resistance | Q24628384 |
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning | Q24652742 | ||
Ribosomal Antibiotics: Contemporary Challenges | Q26745532 | ||
A brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruits | Q26823889 | ||
Resistance to linezolid caused by modifications at its binding site on the ribosome | Q27006772 | ||
Designing Safer and Greener Antibiotics | Q27022324 | ||
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution | Q27626400 | ||
Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution | Q27627220 | ||
Structure of the 30S ribosomal subunit | Q27627261 | ||
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics | Q27627265 | ||
The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit | Q27629321 | ||
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. | Q27631119 | ||
Structure of ribosomal protein TL5 complexed with RNA provides new insights into the CTC family of stress proteins | Q27632703 | ||
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria | Q27635569 | ||
High resolution structure of the large ribosomal subunit from a mesophilic eubacterium | Q27636568 | ||
Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression | Q27640330 | ||
Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants | Q27641602 | ||
Presence of variations in ribosomal protein L16 corresponding to susceptibility of enterococci to oligosaccharides (Avilamycin and evernimicin). | Q39475744 | ||
Multidrug-resistant Enterococcus faecium. An untreatable nosocomial pathogen | Q40397051 | ||
The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes. | Q40588080 | ||
Mutations in the bacterial ribosomal protein l3 and their association with antibiotic resistance. | Q40676510 | ||
Structural rearrangements of a polyketide synthase module during its catalytic cycle | Q41456081 | ||
Structure of a modular polyketide synthase | Q41608053 | ||
A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism | Q41872353 | ||
Selective protein synthesis by ribosomes with a drug-obstructed exit tunnel | Q44890226 | ||
Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin | Q45156906 | ||
Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance | Q46455040 | ||
Molecular basis of fusB-mediated resistance to fusidic acid in Staphylococcus aureus. | Q46877406 | ||
Cryocrystallography of ribosomal particles | Q47584452 | ||
Polar bears, antibiotics, and the evolving ribosome (Nobel Lecture). | Q48307712 | ||
The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. | Q50900973 | ||
Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible. | Q50924008 | ||
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. | Q52930336 | ||
A tunnel in the large ribosomal subunit revealed by three-dimensional image reconstruction | Q69004129 | ||
Where will new antibiotics come from? | Q79817299 | ||
SnapShot: Antibiotic inhibition of protein synthesis I | Q84574037 | ||
The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole | Q27643897 | ||
Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity | Q27644059 | ||
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling | Q27646911 | ||
A Steric Block in Translation Caused by the Antibiotic Spectinomycin | Q27647153 | ||
Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin | Q27650303 | ||
Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit | Q27650650 | ||
Structural basis for hygromycin B inhibition of protein biosynthesis | Q27650910 | ||
The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics | Q27658997 | ||
The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome | Q27659850 | ||
Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action | Q27664697 | ||
Revisiting the structures of several antibiotics bound to the bacterial ribosome | Q27664704 | ||
Crystal structure of the eukaryotic ribosome | Q27666069 | ||
Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit | Q27666800 | ||
Antibiotic resistance is ancient | Q27672681 | ||
Structural basis for TetM-mediated tetracycline resistance | Q27673851 | ||
The structure of the eukaryotic ribosome at 3.0 Å resolution | Q27675638 | ||
Mechanism of tetracycline resistance by ribosomal protection protein Tet(O) | Q27676345 | ||
The Antibiotic Thermorubin Inhibits Protein Synthesis by Binding to Inter-Subunit Bridge B2a of the Ribosome | Q27676704 | ||
A new understanding of the decoding principle on the ribosome | Q27678131 | ||
Identification of the molecular attributes required for aminoglycoside activity against Leishmania | Q27679272 | ||
Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide | Q27682411 | ||
The bacterial ribosome as a target for antibiotics | Q28279726 | ||
Antibiotics for emerging pathogens | Q29615377 | ||
Origins and evolution of antibiotic resistance | Q29617791 | ||
Macrolide antibiotics allosterically predispose the ribosome for translation arrest | Q30584257 | ||
Novel avilamycin derivatives with improved polarity generated by targeted gene disruption | Q30970624 | ||
Personalized Nutrition by Prediction of Glycemic Responses. | Q33445995 | ||
Selection of small peptides, inhibitors of translation | Q33478199 | ||
The antituberculosis antibiotic capreomycin inhibits protein synthesis by disrupting interaction between ribosomal proteins L12 and L10. | Q33622886 | ||
The shared antibiotic resistome of soil bacteria and human pathogens | Q33804392 | ||
Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations. | Q34049640 | ||
Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational modifications on ribosomal nascent proteins. | Q34107147 | ||
Multidrug-resistant to extensively drug resistant tuberculosis: what is next? | Q37390251 | ||
Regulation of gene expression by macrolide-induced ribosomal frameshifting | Q37418561 | ||
Long-term nonsense suppression therapy moderates MPS I-H disease progression. | Q37619694 | ||
The A-Z of bacterial translation inhibitors | Q37636017 | ||
Call of the wild: antibiotic resistance genes in natural environments | Q37700168 | ||
Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action | Q37970718 | ||
Elements of ribosomal drug resistance and specificity. | Q38043799 | ||
Ribosome-targeting antibiotics and mechanisms of bacterial resistance. | Q38171225 | ||
Probing the initiation complex formation on E coli ribosomes using short complementary DNA oligomers | Q38334574 | ||
Effects of antisense DNA against the alpha-sarcin stem-loop structure of the ribosomal 23S rRNA. | Q38352201 | ||
Structure and Function of the Mitochondrial Ribosome | Q38792620 | ||
Electrochemically monitoring the antibiotic susceptibility of Pseudomonas aeruginosa biofilms. | Q38961144 | ||
Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic | Q34248263 | ||
Sequential multiplex PCR approach for determining capsular serotypes of Streptococcus pneumoniae isolates | Q34315537 | ||
Sequence selectivity of macrolide-induced translational attenuation | Q34442039 | ||
Increased selectivity toward cytoplasmic versus mitochondrial ribosome confers improved efficiency of synthetic aminoglycosides in fixing damaged genes: a strategy for treatment of genetic diseases caused by nonsense mutations | Q34475657 | ||
Structure-based drug design meets the ribosome | Q34489129 | ||
Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus | Q34497915 | ||
The general mode of translation inhibition by macrolide antibiotics | Q34526342 | ||
Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding | Q34543629 | ||
Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome | Q34580969 | ||
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing | Q34630593 | ||
Mechanisms of antibiotic resistance in Staphylococcus aureus | Q34657311 | ||
High-resolution structures of large ribosomal subunits from mesophilic eubacteria and halophilic archaea at various functional States | Q34948150 | ||
Environmental pollution by antibiotics and by antibiotic resistance determinants | Q34989442 | ||
Inactivation of the indigenous methyltransferase RlmN in Staphylococcus aureus increases linezolid resistance | Q35005203 | ||
Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases | Q35007821 | ||
A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit. | Q35037268 | ||
Role of antibiotic ligand in nascent peptide-dependent ribosome stalling | Q35081639 | ||
Antibiotics acting on the translational machinery | Q35086152 | ||
Bactobolin A binds to a site on the 70S ribosome distinct from previously seen antibiotics | Q35095601 | ||
Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA | Q35101167 | ||
Low fitness cost of the multidrug resistance gene cfr. | Q35139469 | ||
Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution | Q35567060 | ||
High-resolution structure of the Escherichia coli ribosome. | Q35598643 | ||
Oxacillin sensitization of methicillin-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus pseudintermedius by antisense peptide nucleic acids in vitro | Q35839071 | ||
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria | Q36000911 | ||
A platform for the discovery of new macrolide antibiotics. | Q36021739 | ||
Species-specific antibiotic-ribosome interactions: implications for drug development | Q36334935 | ||
Multidrug-resistance efflux pumps - not just for resistance | Q36538111 | ||
Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors | Q36593851 | ||
Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. | Q36701091 | ||
Erythromycin Resistance Peptides Selected from Random Peptide Libraries | Q36869393 | ||
Structural basis for cross-resistance to ribosomal PTC antibiotics | Q37020720 | ||
Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome | Q37086516 | ||
Advances in MRSA drug discovery: where are we and where do we need to be? | Q37112508 | ||
Programmed drug-dependent ribosome stalling | Q37378026 | ||
P921 | main subject | antibiotic | Q12187 |
P1104 | number of pages | 17 | |
P304 | page(s) | 567-583 | |
P577 | publication date | 2017-06-01 | |
P1433 | published in | Annual Review of Biochemistry | Q567356 |
P1476 | title | A Bright Future for Antibiotics? | |
P478 | volume | 86 |
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