Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?

scientific article published on 28 December 2015

Prognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed? is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JOIM.12455
P698PubMed publication ID26709197

P50authorMattias MattssonQ85925915
P2093author name stringR Rosenquist
P Baliakas
K Stamatopoulos
P2860cites workGuidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelinesQ24616084
Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolutionQ26823586
TP53 mutation and survival in chronic lymphocytic leukemiaQ27851577
Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemiaQ27851685
Recurrent mutations refine prognosis in chronic lymphocytic leukemia.Q27853022
Chronic lymphocytic leukemia: 2015 Update on diagnosis, risk stratification, and treatmentQ28082086
Genomic aberrations and survival in chronic lymphocytic leukemiaQ28141442
Chronic lymphocytic leukemiaQ28236621
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemiaQ28279141
Idelalisib and rituximab in relapsed chronic lymphocytic leukemiaQ28306347
Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemiaQ28394721
Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractorinessQ29013141
Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemiaQ29620690
Chromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic dataQ30685440
Chronic lymphocytic leukemia in young (≤ 55 years) patients: a comprehensive analysis of prognostic factors and outcomesQ33558148
Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemiaQ33595764
The clinical significance of patients' sex in chronic lymphocytic leukemiaQ33695983
Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemiaQ33957743
Richter's transformation in chronic lymphocytic leukemia.Q34112617
A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysisQ34282319
Development of a comprehensive prognostic index for patients with chronic lymphocytic leukemiaQ34418874
Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemiaQ34805491
B-cell clones as early markers for chronic lymphocytic leukemiaQ34943783
Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerationsQ35029461
Detailed analysis of therapy-driven clonal evolution of TP53 mutations in chronic lymphocytic leukemiaQ35407650
Three-year follow-up of treatment-naïve and previously treated patients with CLL and SLL receiving single-agent ibrutinibQ35450520
Experience with rituximab immunotherapy as an early intervention in patients with Rai stage 0 to II chronic lymphocytic leukemiaQ35461949
NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLLQ35794466
Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapiesQ36083000
Sex differences in incidence and outcome of chronic lymphocytic leukemia patientsQ36590969
Evolution and impact of subclonal mutations in chronic lymphocytic leukemiaQ36619124
Relevance of the immunoglobulin VH somatic mutation status in patients with chronic lymphocytic leukemia treated with fludarabine, cyclophosphamide, and rituximab (FCR) or related chemoimmunotherapy regimensQ37028643
Validation of a new prognostic index for patients with chronic lymphocytic leukemiaQ37068125
Monoclonal B-cell lymphocytosis (MBL): biology, natural history and clinical managementQ37552813
Molecular genetics of high-risk chronic lymphocytic leukemiaQ38065304
Uncovering the DNA methylome in chronic lymphocytic leukemiaQ38074267
Prognostic markers and their clinical applicability in chronic lymphocytic leukemia: where do we stand?Q38088354
Richter syndromeQ38135347
The complex interplay between cell-intrinsic and cell-extrinsic factors driving the evolution of chronic lymphocytic leukemiaQ38473614
Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre studyQ39876261
Prognostic impact and landscape of NOTCH1 mutations in chronic lymphocytic leukemia (CLL): a study on 852 patientsQ43555954
Prognostic nomogram and index for overall survival in previously untreated patients with chronic lymphocytic leukemiaQ44904842
Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial.Q45915574
Definition of progression risk based on combinations of cellular and molecular markers in patients with Binet stage A chronic lymphocytic leukaemiaQ47812640
A B-cell epigenetic signature defines three biologic subgroups of chronic lymphocytic leukemia with clinical impact.Q50784932
Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia.Q52621343
SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients.Q52644149
Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: implications for the role of antigen selection in leukemogenesis.Q53029323
Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia.Q53596463
Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.Q54580268
Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope.Q54789536
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
lymphocyteQ715347
P304page(s)347-357
P577publication date2015-12-28
P1433published inJournal of Internal MedicineQ6295387
P1476titlePrognostic indices in chronic lymphocytic leukaemia: where do we stand how do we proceed?
P478volume279

Reverse relations

cites work (P2860)
Q38998146Antigen receptor stereotypy in chronic lymphocytic leukemia.
Q40784167CD49d prevails over the novel recurrent mutations as independent prognosticator of overall survival in chronic lymphocytic leukemia.
Q64091853Cytogenetic complexity in chronic lymphocytic leukemia: definitions, associations, and clinical impact
Q58561791Effectiveness of the Combination of Rituximab and Standard Chemotherapeutic Regimens in Previously Untreated Patients with Chronic Lymphocytic Leukaemia in Real-Life: Results from a Noninterventional Study (CILI Study)
Q38669131Genetic landscape and deregulated pathways in B-cell lymphoid malignancies
Q91753087Guidelines for Diagnosis and Treatment of Chronic Lymphocytic Leukemia. Krohem B-Cll 2017
Q60932287Limited value of routine follow-up visits in chronic lymphocytic leukemia managed initially by watch and wait: A North Denmark population-based study
Q49692075Management of high risk chronic lymphocytic leukaemia (CLL) patients in Australia
Q92890447Methylation alteration of SHANK1 as a predictive, diagnostic and prognostic biomarker for chronic lymphocytic leukemia
Q42378526Next-generation sequencing in chronic lymphocytic leukemia: recent findings and new horizons.
Q89637413Prognostic model for newly diagnosed CLL patients in Binet stage A: results of the multicenter, prospective CLL1 trial of the German CLL study group
Q61803940Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia
Q55077967The International Prognostic Index for Patients with Chronic Lymphocytic Leukemia Has the Higher Value in Predicting Overall Outcome Compared with the Barcelona-Brno Biomarkers Only Prognostic Model and the MD Anderson Cancer Center Prognostic Index