Anticancer effects of the microbiome and its products

scientific article published on 22 May 2017

Anticancer effects of the microbiome and its products is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P6179Dimensions Publication ID1085463395
P356DOI10.1038/NRMICRO.2017.44
P698PubMed publication ID28529325

P50authorGuido KroemerQ19508945
Laurence ZitvogelQ28317098
Romain DaillèreQ40255955
Maria P RobertiQ93087262
Bertrand RoutyQ96103030
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse modelQ24654226
Role of the microbiome in non-gastrointestinal cancersQ26747710
Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial EnzymeQ27665609
Global cancer statistics, 2012Q27860501
Resurrecting the intestinal microbiota to combat antibiotic-resistant pathogensQ28075653
The hallmarks of agingQ28131641
Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young womenQ28251260
The three Es of cancer immunoeditingQ28251475
Aldara activates TLR7-independent immune defenceQ28286677
Characterizing human lung tissue microbiota and its relationship to epidemiological and clinical featuresQ28595730
Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndromeQ28645773
Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upregulation of gut bacterial polyamine productionQ28741377
Microbial influences in inflammatory bowel diseasesQ29614264
Induction of autophagy by spermidine promotes longevityQ29614498
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasisQ29616351
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cellsQ29618126
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generationQ29620116
Synchronized cycles of bacterial lysis for in vivo deliveryQ37307560
Fecal microbiota transplantation for patients with steroid-resistant acute graft-versus-host disease of the gut.Q37376599
Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.Q37503122
16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatmentQ37588284
Limitations in doxorubicin production from Streptomyces peucetiusQ37684107
An inulin and doxorubicin conjugate for improving cancer therapyQ37699469
EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013.Q38119345
Pore-forming toxins: ancient, but never really out of fashionQ38660364
Caloric Restriction Mimetics Enhance Anticancer ImmunosurveillanceQ38758370
Targeting Cancer Metabolism: Dietary and Pharmacologic InterventionsQ38792334
The Intestinal Microbiome and Estrogen Receptor-Positive Female Breast CancerQ38815561
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host MetabolismQ38869873
Anti-tumour immune effect of oral administration of Lactobacillus plantarum to CT26 tumour-bearing miceQ38876416
TLR7 promotes tumor progression, chemotherapy resistance, and poor clinical outcomes in non-small cell lung cancerQ38970486
Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancerQ38971333
Inhibition of Growth and Metastasis of Breast Cancer in Mice by Milk Fermented With Lactobacillus casei CRL 431.Q39008590
Probiotic Lactobacillus acidophilus and L. casei mix sensitize colorectal tumoral cells to 5-fluorouracil-induced apoptosisQ39720166
Differential induction of apoptosis in human colonic carcinoma cells (Caco-2) by Atopobium, and commensal, probiotic and enteropathogenic bacteria: mediation by the mitochondrial pathway.Q39758852
Mediterranean diet and faecal microbiota: a transversal studyQ39802329
Relationship between the in vitro response of dendritic cells to Lactobacillus and prevention of tumorigenesis in the mouseQ39937334
Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria.Q40189042
Antibiotic-Induced Changes in the Intestinal Microbiota and DiseaseQ36948447
Beneficial bacteria inhibit cachexiaQ37022010
Characterization of the microbiome of nipple aspirate fluid of breast cancer survivorsQ37024095
Lactobacillus rhamnosus GG Activation of Dendritic Cells and Neutrophils Depends on the Dose and Time of ExposureQ37147460
The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant DiseaseQ37147989
Non-absorbable apple procyanidins prevent obesity associated with gut microbial and metabolomic changesQ37163306
The long-term stability of the human gut microbiotaQ37217949
Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivationQ37237047
Immunogenic cell death in cancer therapyQ29620118
Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma.Q30358552
Compositional data analysis of the microbiome: fundamentals, tools, and challengesQ31105136
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamideQ31144277
Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanomaQ33340438
Phase I trial of systemic intravenous infusion of interleukin-13-Pseudomonas exotoxin in patients with metastatic adrenocortical carcinomaQ33421178
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor CytotoxicityQ33554629
Cell-bound exopolysaccharide from probiotic bacteria induces autophagic cell death of tumour cellsQ33600111
Changes in abundance of oral microbiota associated with oral cancerQ33700542
Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondriaQ33957357
Mucosa-associated bacteria in the human gastrointestinal tract are uniformly distributed along the colon and differ from the community recovered from fecesQ34101794
Host-microbial interactions in the metabolism of therapeutic and diet-derived xenobioticsQ34311685
Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells.Q34429647
Association of seropositivity to Helicobacter species and biliary tract cancer in the ATBC studyQ34438569
The potential role of lung microbiota in lung cancer attributed to household coal burning exposuresQ34440594
Mini-review: perspective of the microbiome in the pathogenesis of urothelial carcinomaQ34448175
Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecologyQ34481919
Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug ToxicityQ34493889
The microbiota in adaptive immune homeostasis and diseaseQ34533142
Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancerQ34539541
Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory EffectsQ34542239
Cardioprotection and lifespan extension by the natural polyamine spermidine.Q34544613
Acetate dependence of tumorsQ34745657
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stressQ34978574
Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.Q35050169
Policy: How to regulate faecal transplantsQ35099908
Reprogrammed and transmissible intestinal microbiota confer diminished susceptibility to induced colitis in TMF-/- miceQ35123366
Microbiota modulate tumoral immune surveillance in lung through a γδT17 immune cell-dependent mechanismQ35191621
Immune mechanisms in bacillus Calmette-Guerin immunotherapy for superficial bladder cancer.Q35197371
Safety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer.Q35419821
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responsesQ35446009
Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbesQ35489763
Discordant humoral and cellular immune responses to Cytomegalovirus (CMV) in glioblastoma patients whose tumors are positive for CMV.Q35506920
Mental health: thinking from the gut.Q35567682
The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibitionQ35571641
Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control studyQ40501515
Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial PeptidoglycanQ40626889
Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria.Q41583397
Acetate is a bioenergetic substrate for human glioblastoma and brain metastasesQ41667697
Anti-cancer activity of targeted pro-apoptotic peptidesQ41688099
Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal CancerQ41713919
Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosisQ41731982
Microbial-derived butyrate: an oncometabolite or tumor-suppressive metabolite?Q42003419
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretomeQ42257409
Nontoxic potentiation of cancer chemotherapy by dietary oligofructose or inulinQ42503968
Immunomodulatory and antitumor effects in vivo by the cytoplasmic fraction of Lactobacillus casei and Bifidobacterium longum.Q42830585
Continuous intravenous administration of live genetically modified salmonella typhimurium in patients with metastatic melanomaQ43161957
Enhancement of natural killer cytotoxicity delayed murine carcinogenesis by a probiotic microorganismQ43564045
Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patientsQ44591603
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22.Q45760347
Probiotic potential of lactic acid bacteria isolated from fermented dairy milks on antiproliferation of colon cancer cellsQ46179052
Does an apple a day keep the oncologist away?Q46642945
Estimation of the potential antitumor activity of microencapsulated Lactobacillus acidophilus yogurt formulation in the attenuation of tumorigenesis in Apc(Min/+) miceQ47447621
The treatment of malignant tumors by bacterial toxins as developed by the late William B. Coley, M.D., reviewed in the light of modern researchQ47779608
Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant gliomaQ48209763
Tumor regression with regional distribution of the targeted toxin TF-CRM107 in patients with malignant brain tumorsQ48587395
Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats.Q50429019
AhR sensing of bacterial pigments regulates antibacterial defence.Q52874611
Butyrate production from high-fiber diet protects against lymphoma tumor.Q53172774
Lactobacillus casei BL23 regulates Treg and Th17 T-cell populations and reduces DMH-associated colorectal cancer.Q53214867
Orally delivered microencapsulated probiotic formulation favorably impacts polyp formation in APC (Min/+) model of intestinal carcinogenesis.Q53233595
Synbiotic intervention of Bifidobacterium lactis and resistant starch protects against colorectal cancer development in rats.Q53307288
[Influence of Lactobacillus casei on rat bladder carcinogenesis].Q53472978
Tumor Immunity Produced by the Intradermal Inoculation of Living Tumor Cells and Living Mycobacterium bovis (Strain BCG)Q54053579
Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype.Q54292519
Expression of chemokine/cytokine genes and immune cell recruitment following the instillation of Mycobacterium bovis, bacillus Calmette-Guérin or Lactobacillus rhamnosus strain GG in the healthy murine bladder.Q54549677
Antibiotic use predicts an increased risk of cancerQ57303274
Prognostic Impact of Vitamin B6 Metabolism in Lung CancerQ57832558
Habitual Intake of Lactic Acid Bacteria and Risk Reduction of Bladder CancerQ58873671
Bacillus Calmette-Guerin versus doxorubicin versus thiotepa: a randomized prospective study in 202 patients with superficial bladder cancerQ67271686
Prophylactic effect of a Lactobacillus casei preparation on the recurrence of superficial bladder cancer. BLP Study GroupQ67966831
Antitumor activity of Lactobacillus casei in miceQ71578136
Effects of oral administration of Lactobacillus casei on antitumor responses induced by tumor resection in miceQ72346645
Antitumor effects of the intravesical instillation of heat killed cells of the Lactobacillus casei strain Shirota on the murine orthotopic bladder tumor MBT-2Q77131178
Lactobacillus species is more cytotoxic to human bladder cancer cells than Mycobacterium Bovis (bacillus Calmette-Guerin)Q78413105
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligandsQ80591503
Effect of hydrogen peroxide of bacterial origin on apoptosis and necrosis of gut mucosa epithelial cells as a possible pathomechanism of inflammatory bowel disease and cancerQ83180528
An intra-patient placebo-controlled phase I trial to evaluate the safety and tolerability of intradermal IMM-101 in melanomaQ84963994
Engineering Bacillus subtilis for the conversion of the antimetabolite 4-hydroxy-l-threonine to pyridoxineQ35578887
Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man studyQ35592471
Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled TrialQ35598580
High throughput sequencing reveals distinct microbial populations within the mucosal and luminal niches in healthy individualsQ35615264
The yin yang of bacterial polysaccharides: lessons learned from B. fragilis PSAQ35627540
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and ImmunityQ35634752
Gut mucosal microbiome across stages of colorectal carcinogenesis.Q35826754
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacyQ35833912
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiotaQ35833921
Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversityQ35843279
From Hype to Hope: The Gut Microbiota in Enteric Infectious DiseaseQ35861517
Gut Microbiota Orchestrates Energy Homeostasis during Cold.Q35861523
Genetic and Metabolic Signals during Acute Enteric Bacterial Infection Alter the Microbiota and Drive Progression to Chronic Inflammatory DiseaseQ35893552
Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.Q35901034
Intestinal microbiome analyses identify melanoma patients at risk for checkpoint-blockade-induced colitisQ35912366
Cervical Microbiota Associated with Higher Grade Cervical Intraepithelial Neoplasia in Women Infected with High-Risk Human PapillomavirusesQ35943509
Human symbionts inject and neutralize antibacterial toxins to persist in the gutQ35950477
Gut microbiome-derived metabolites modulate intestinal epithelial cell damage and mitigate graft-versus-host diseaseQ35964585
Microbiome and Anticancer ImmunosurveillanceQ35983760
The Colonic Crypt Protects Stem Cells from Microbiota-Derived MetabolitesQ36041507
The probiotic approach: an alternative treatment option in urologyQ36044867
Repertoire of human gut microbesQ36056054
Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapyQ36068286
Abating colon cancer polyposis by Lactobacillus acidophilus deficient in lipoteichoic acidQ36069042
Microbiome-wide association studies link dynamic microbial consortia to diseaseQ36069076
Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated CholangiocarcinomaQ36080191
Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancerQ36082731
Gastrointestinal microbial populations can distinguish pediatric and adolescent Acute Lymphoblastic Leukemia (ALL) at the time of disease diagnosis.Q36104405
Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon CarcinogenesisQ36117973
Trial Watch: Experimental Toll-like receptor agonists for cancer therapyQ36194849
A bacterial carbohydrate links innate and adaptive responses through Toll-like receptor 2.Q36228174
Production of butyrate from lysine and the Amadori product fructoselysine by a human gut commensalQ36419656
Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in miceQ36658938
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectmicrobiomeQ1330402
P304page(s)465-478
P577publication date2017-05-22
P1433published inNature Reviews MicrobiologyQ1071797
P1476titleAnticancer effects of the microbiome and its products
P478volume15

Reverse relations

cites work (P2860)
Q64102200A review of 10 years of human microbiome research activities at the US National Institutes of Health, Fiscal Years 2007-2016
Q92586194Antibiotics are associated with decreased progression-free survival of advanced melanoma patients treated with immune checkpoint inhibitors
Q98725969Bowel inflammation in cancer patients: the microbiome, antibiotics and interleukin-9
Q49594865Cancer immunotherapy in 2017: The breakthrough of the microbiota
Q90460882Characterization of the Anti-Cancer Activity of the Probiotic Bacterium Lactobacillus fermentum Using 2D vs. 3D Culture in Colorectal Cancer Cells
Q56889453Checkpoint Inhibitors: Conquering Cancer with a Little (T)-Help from Our Microbial Friends
Q98165144Combination of Detoxified Pneumolysin Derivative ΔA146Ply and Berbamine as a Treatment Approach for Breast Cancer
Q55012882Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy.
Q59161744Culturing the human microbiota and culturomics
Q91884674Current understanding of gut microbiota alterations and related therapeutic intervention strategies in heart failure
Q64102188Dysbiosis of the Gut Microbiome in Lung Cancer
Q99552018Elucidating the gut microbiota composition and the bioactivity of immunostimulatory commensals for the optimization of immune checkpoint inhibitors
Q57476181Enlisting commensal microbes to resist antibiotic-resistant pathogens
Q99578627Exploring the food-gut axis in immunotherapy response of cancer patients
Q40132867Fatty is not that bad: feeding short-chain fatty acids to restrain autoimmunity
Q93013941Fecal Akkermansia muciniphila Is Associated with Body Composition and Microbiota Diversity in Overweight and Obese Women with Breast Cancer Participating in a Presurgical Weight Loss Trial
Q99569163Gut Microbes' Impact on Oncogenic Drivers: Location Matters
Q92070062Gut Microbiome and the Response to Immunotherapy in Cancer
Q98178297Gut Microbiota Profiling in Patients With HER2-Negative Metastatic Breast Cancer Receiving Metronomic Chemotherapy of Capecitabine Compared to Those Under Conventional Dosage
Q61806850Gut Microbiota and Cancer: From Pathogenesis to Therapy
Q90682838Gut bacteria affect the tumoral immune milieu: distorting the efficacy of immunotherapy or not?
Q55240704Gut microbiome modulates efficacy of immune checkpoint inhibitors.
Q57065819Gut microbiome profiling and colorectal cancer in African Americans and Caucasian Americans
Q57113484Gut microbiota bile acid metabolism controls cancer immunosurveillance
Q90289012Gut microbiota in colorectal cancer: mechanisms of action and clinical applications
Q49958101Gut microbiota injury in allogeneic haematopoietic stem cell transplantation
Q91798966Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response
Q91971762HIV, Cancer, and the Microbiota: Common Pathways Influencing Different Diseases
Q92094096Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
Q47161100How Mucosal Epithelia Deal with Stress: Role of NKG2D/NKG2D Ligands during Inflammation.
Q89599356Immune Responses Raised in an Experimental Colon Carcinoma Model Following Oral Administration of Lactobacillus casei
Q92482391Ingestion of Non-digestible Carbohydrates From Plant-Source Foods and Decreased Risk of Colorectal Cancer: A Review on the Biological Effects and the Mechanisms of Action
Q90702676Inhibitory effects of viral infection on cancer development
Q90163614Intestinal Microbiota: A Novel Target to Improve Anti-Tumor Treatment?
Q61446623Klebsiella pneumoniae prevents spore germination and hyphal development of Aspergillus species
Q64118375Mechanistic Insights Into Probiotic Properties of Lactic Acid Bacteria Associated With Ethnic Fermented Dairy Products
Q90051711Microbiota-Propelled T Helper 17 Cells in Inflammatory Diseases and Cancer
Q91321458Modulating the microbiome to improve therapeutic response in cancer
Q58726363Mucosal microbiota of intestinal polyps reveals putative biomarkers of colorectal cancer
Q93052035Multiple Sclerosis and Cancer: The Ying-Yang Effect of Disease Modifying Therapies
Q52928868Optically-controlled bacterial metabolite for cancer therapy.
Q90746050Pancreatic Cancer, Gut Microbiota, and Therapeutic Efficacy
Q40039516Potential contribution of gut microbiota and systemic inflammation on HIV vaccine effectiveness and vaccine design
Q99605164Predicting Response to Immunotherapy in Metastatic Renal Cell Carcinoma
Q92383050Priorities for the next 10 years of human microbiome research
Q55400961Profiling the Urinary Microbiota in Male Patients With Bladder Cancer in China.
Q91670292Protective Role of Fecal Microbiota Transplantation on Colitis and Colitis-Associated Colon Cancer in Mice Is Associated With Treg Cells
Q55259937Proteinaceous Secretory Metabolites of Probiotic Human Commensal Enterococcus hirae 20c, E. faecium 12a and L12b as Antiproliferative Agents Against Cancer Cell Lines.
Q64113253Role of Gut Microbiota in the Pharmacological Effects of Natural Products
Q90225030Role of Zinc in Immune System and Anti-Cancer Defense Mechanisms
Q49793201Starvation, Stress Resistance, and Cancer
Q90479321Study of the cwaRS-ldcA Operon Coding a Two-Component System and a Putative L,D-Carboxypeptidase in Lactobacillus paracasei
Q90218826The Cross-Talk Between Gut Microbiota and Lungs in Common Lung Diseases
Q89727343The Influence of Lung Microbiota on Lung Carcinogenesis, Immunity, and Immunotherapy
Q60920745The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma
Q93016881The Role of the Canine Gut Microbiome and Metabolome in Health and Gastrointestinal Disease
Q57801565The impact of counseling on nutritional status among hematopoietic stem cell recipients: results of a randomized controlled trial
Q57997662The intimate relationship between gut microbiota and cancer immunotherapy
Q92180014The microbiome, cancer, and cancer therapy
Q91297745The next step towards anticancer microbiota therapeutics
Q58783075The urinary microbiome associated with bladder cancer
Q94544748Traditional Chinese Medicine and Gut Microbiome: Their Respective and Concert Effects on Healthcare
Q99552007Trial watch : the gut microbiota as a tool to boost the clinical efficacy of anticancer immunotherapy
Q47393365Trial watch: Immune checkpoint blockers for cancer therapy
Q92642258Use of Antibiotics and Risk of Cancer: A Systematic Review and Meta-Analysis of Observational Studies

Search more.