The effect of blinding on estimates of mortality in randomised clinical trials of intensive care interventions: protocol for a systematic review and meta-analysis

scientific article published on 11 July 2017

The effect of blinding on estimates of mortality in randomised clinical trials of intensive care interventions: protocol for a systematic review and meta-analysis is …
instance of (P31):
scholarly articleQ13442814
meta-analysisQ815382

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P356DOI10.1136/BMJOPEN-2017-016187
P932PMC publication ID5541632
P698PubMed publication ID28701412

P50authorCarl Thomas AnthonQ59117079
Morten Hylander MøllerQ87875689
Anders PernerQ43973788
Anders GranholmQ49702507
Jon H LaakeQ56333900
P2860cites workBlinding was judged more difficult to achieve and maintain in nonpharmacologic than pharmacologic trialsQ57286644
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Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statementQ21195843
Statistics notes: blinding in clinical trials and other studiesQ24524794
Effects of suggestion and conditioning on the action of chemical agents in human subjects; the pharmacology of placebosQ24562956
Empirical evidence of bias in treatment effect estimates in controlled trials with different interventions and outcomes: meta-epidemiological studyQ24653790
Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trialsQ27860735
GRADE: an emerging consensus on rating quality of evidence and strength of recommendationsQ27860753
GRADE guidelines: 3. Rating the quality of evidenceQ29547891
Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanationQ29615706
Systematic reviews in health care: Assessing the quality of controlled clinical trialsQ29618659
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"Do not resuscitate" decisions in acute respiratory distress syndrome. A secondary analysis of clinical trial dataQ30868744
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Impact of quality of evidence on the strength of recommendations: an empirical studyQ33484962
The ethical problems with sham surgery in clinical researchQ33739165
Physician interpretations and textbook definitions of blinding terminology in randomized controlled trialsQ33942896
The impact of blinding on the results of a randomized, placebo-controlled multiple sclerosis clinical trialQ34348362
How important are comprehensive literature searches and the assessment of trial quality in systematic reviews? Empirical study.Q35065178
Bias in clinical intervention research.Q36380552
GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomesQ38006189
Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological studiesQ38044510
Mortality in Multicenter Critical Care Trials: An Analysis of Interventions With a Significant Effect.Q41141860
Practical tips for surgical research: blinding: who, what, when, why, how?Q42077047
Single-blind randomized clinical trial of laparoscopic versus open appendicectomy in childrenQ43572289
Blinding in randomised trials: hiding who got whatQ52937785
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)e016187
P577publication date2017-07-11
P1433published inBMJ OpenQ17003470
P1476titleThe effect of blinding on estimates of mortality in randomised clinical trials of intensive care interventions: protocol for a systematic review and meta-analysis
P478volume7

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