MiR-125b increases nasopharyngeal carcinoma radioresistance by targetingA20/NF-κB signaling pathway

scientific article published on 11 July 2017

MiR-125b increases nasopharyngeal carcinoma radioresistance by targetingA20/NF-κB signaling pathway is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

External links are
P356DOI10.1158/1535-7163.MCT-17-0385
P698PubMed publication ID28698199

P2093author name stringWei Huang
Hong Yi
Jia-Quan Qu
Xin-Hui Li
Zhi-Qiang Xiao
Zhen Zheng
Shan-Shan Lu
Hong-Mei Yi
Li-Na Li
Ta Xiao
Xu Ye
P2860cites workDe-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signallingQ24299573
Widespread changes in protein synthesis induced by microRNAsQ27860886
Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-RasQ28267417
MicroRNAs in CancerQ29615539
Targeting A20 decreases glioma stem cell survival and tumor growthQ33534629
Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repairQ34365755
Silencing of microRNA-21 confers radio-sensitivity through inhibition of the PI3K/AKT pathway and enhancing autophagy in malignant glioma cell linesQ34450866
Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexesQ34512302
Frequent inactivation of A20 in B-cell lymphomasQ34607223
Oncomir miR-125b suppresses p14(ARF) to modulate p53-dependent and p53-independent apoptosis in prostate cancerQ34667906
The role of p53 in determining sensitivity to radiotherapyQ35058584
Frequent down regulation of the tumor suppressor gene a20 in multiple myelomaQ35598382
Focus on nasopharyngeal carcinomaQ35773862
A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastomaQ35967192
MicroRNAs miR-125a and miR-125b constitutively activate the NF-κB pathway by targeting the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20)Q35974211
MiR-205 determines the radioresistance of human nasopharyngeal carcinoma by directly targeting PTEN.Q35974749
NF-kappa B-mediated adaptive resistance to ionizing radiationQ36493029
MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines.Q36738067
NF-κB regulates radioresistance mediated by β1-integrin in three-dimensional culture of breast cancer cellsQ36974768
NF-κB Signaling Regulates Expression of Epstein-Barr Virus BART MicroRNAs and Long Noncoding RNAs in Nasopharyngeal Carcinoma.Q37073277
OCT4 promotes tumorigenesis and inhibits apoptosis of cervical cancer cells by miR-125b/BAK1 pathwayQ37148223
The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathologyQ37567071
miR-125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20.Q37694685
A20: from ubiquitin editing to tumour suppressionQ37728850
Targeting inflammatory pathways for tumor radiosensitization.Q37769804
Expanding role of ubiquitination in NF-κB signalingQ37816941
Regulation of NF-κB signaling by the A20 deubiquitinaseQ37985541
Potential use of nucleic acid-based agents in the sensitization of nasopharyngeal carcinoma to radiotherapyQ38000925
miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers.Q38769727
Significance of NF-κB activation in immortalization of nasopharyngeal epithelial cells.Q38835290
MiRNA-203 Reduces Nasopharyngeal Carcinoma Radioresistance by Targeting IL8/AKT SignalingQ38841088
5-lipoxygenase is a direct target of miR-19a-3p and miR-125b-5pQ38919945
MiR-125b promotes cell migration and invasion by targeting PPP1CA-Rb signal pathways in gastric cancer, resulting in a poor prognosisQ38954738
Apogossypolone, a small-molecule inhibitor of Bcl-2, induces radiosensitization of nasopharyngeal carcinoma cells by stimulating autophagyQ38985787
miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1.Q39075026
MicroRNA 23b regulates autophagy associated with radioresistance of pancreatic cancer cellsQ39115100
Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma.Q39123741
MicroRNA-324-3p regulates nasopharyngeal carcinoma radioresistance by directly targeting WNT2B.Q39167154
MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD geneQ39305395
miR-29c targets TNFAIP3, inhibits cell proliferation and induces apoptosis in hepatitis B virus-related hepatocellular carcinoma.Q39505900
Identification of biomarkers for predicting nasopharyngeal carcinoma response to radiotherapy by proteomics.Q39712629
Functional characterization of p53 in nasopharyngeal carcinoma by stable shRNA expression.Q39872621
Ionizing radiation-induced NF-kappaB activation requires PARP-1 function to confer radioresistanceQ39908141
MicroRNA-125b regulates microglia activation and motor neuron death in ALS.Q41517777
Interplay between RNA-binding protein HuR and microRNA-125b regulates p53 mRNA translation in response to genotoxic stressQ41827348
NF-κB in cancer: a matter of life and deathQ42229340
The World Health Organization histological classification of tumours of the upper respiratory tract and ear. A commentary on the second edition.Q53390075
Nasopharyngeal carcinoma. Treatment planning with IMRT and 3D conformal radiotherapyQ62096583
Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976-1985: overall survival and patterns of failureQ68127789
A comparison between the Chinese 2008 and the 7th edition AJCC staging systems for nasopharyngeal carcinomaQ86639995
P921main subjectNF-κBQ411114
P577publication date2017-07-11
P1433published inMolecular Cancer TherapeuticsQ2363144
P1476titleMiR-125b increases nasopharyngeal carcinoma radioresistance by targetingA20/NF-κB signaling pathway

Reverse relations

cites work (P2860)
Q103749799Anti-mastitis SNV identification of NFκB1 in Chinese Holstein cows and the possible anti-inflammation role of NFκB1/p105 in bovine MECs
Q58561302CAV3.1 knockdown suppresses cell proliferation, migration and invasion of prostate cancer cells by inhibiting AKT
Q91789056CircRNA ZNF609 Knockdown Suppresses Cell Growth via Modulating miR-188/ELF2 Axis in Nasopharyngeal Carcinoma
Q92715938CircRNA_000543 knockdown sensitizes nasopharyngeal carcinoma to irradiation by targeting miR-9/platelet-derived growth factor receptor B axis
Q91626368Curcumin enhances radiosensitization of nasopharyngeal carcinoma by regulating circRNA network
Q93023212EBV encoded miRNA BART8-3p promotes radioresistance in nasopharyngeal carcinoma by regulating ATM/ATR signaling pathway
Q100962562ELK1 activated-long noncoding RNA LBX2-AS1 aggravates the progression of ovarian cancer through targeting miR-4784/KDM5C axis
Q96614285FOXD1, negatively regulated by miR-186, promotes the proliferation, metastasis and radioresistance of nasopharyngeal carcinoma cells
Q93198768MiRNAs in Radiotherapy Resistance of Nasopharyngeal Carcinoma
Q52608528MicroRNA Roles in the Nuclear Factor Kappa B Signaling Pathway in Cancer.
Q90698082MicroRNA-212 suppresses cell proliferation in nasopharyngeal carcinoma by targeting ELF3
Q94526791Multiple Mechanisms Involving in Radioresistance of Nasopharyngeal Carcinoma
Q92272427Radio-Susceptibility of Nasopharyngeal Carcinoma: Focus on Epstein-Barr virus, MicroRNAs, Long non-coding RNAs and Circular RNAs
Q50181420Rapid detection of quantum dot immune chromatography nasopharyngeal carcinoma EBNA1 antibody.
Q58568433Retraction: MiR-125b Increases Nasopharyngeal Carcinoma Radioresistance By Targeting A20/NF-κB Signaling Pathway
Q92616932The clinicopathological significance of decreased miR-125b-5p in hepatocellular carcinoma: evidence based on RT-qPCR, microRNA-microarray, and microRNA-sequencing
Q92182116Wnt3a promotes radioresistance via autophagy in squamous cell carcinoma of the head and neck
Q104465390miR‑182‑5p contributes to radioresistance in nasopharyngeal carcinoma by regulating BNIP3 expression