Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study

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Human Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study is …
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scholarly articleQ13442814

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P356DOI10.1093/AJE/KWX087
P932PMC publication ID5860272
P698PubMed publication ID28459968

P50authorSimin LiuQ25999435
Rachel H. MackeyQ38641477
Lewis KullerQ88077314
Kevin D DeaneQ89587685
Mehret Birru TalabiQ89851497
V Michael HolersQ93110324
Yuefang F ChangQ114312027
P2093author name stringLarry W Moreland
William H Robinson
Janice S Dorman
Brian T Walitt
P2860cites workInterleukin-10 and the interleukin-10 receptorQ24290912
Cardiovascular risk factors in women with and without rheumatoid arthritisQ28171426
Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational StudyQ28210408
Emerging patterns of risk factor make-up enable subclassification of rheumatoid arthritisQ28304210
The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritisQ28306666
Predictive value of autoantibody testing for validating self-reported diagnoses of rheumatoid arthritis in the Women's Health InitiativeQ33621133
Interleukins and interleukin receptors in rheumatoid arthritis: Research, diagnostics and clinical implicationsQ34047753
The rheumatoid arthritis HLA-DRB1 shared epitopeQ34067135
Rheumatoid arthritis may be primarily associated with HLA-DR4 molecules sharing a particular sequence at residues 67-74.Q34143883
Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritisQ34401259
Association of DRB1 shared epitope genotypes with early mortality in rheumatoid arthritis: results of eighteen years of followup from the early rheumatoid arthritis studyQ34624148
Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studiesQ34889152
Prediction of radiological outcome in early rheumatoid arthritis in clinical practice: role of antibodies to citrullinated peptides (anti-CCP).Q35554533
A multicentre, randomised, double blind, placebo controlled phase II study of subcutaneous interferon beta-1a in the treatment of patients with active rheumatoid arthritis.Q35554739
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Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritisQ35605524
Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope allelesQ35636886
Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health InitiativeQ36001551
Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a population-based cohort study.Q36031031
MHC class I antigens and immune surveillance in transformed cells.Q36714774
The performance of anti-cyclic citrullinated peptide antibodies in predicting the severity of radiologic damage in inflammatory polyarthritis: results from the Norfolk Arthritis RegisterQ36732099
Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment responseQ37054390
Critical role for granulocyte colony-stimulating factor in inflammatory arthritisQ37388766
Rheumatoid arthritis in the Women's Health Initiative: methods and baseline evaluationQ37671914
Rheumatoid factor as a potentiator of anti-citrullinated protein antibody-mediated inflammation in rheumatoid arthritisQ37715460
High risk of clinical cardiovascular events in rheumatoid arthritis: Levels of associations of myocardial infarction and stroke through a systematic review and meta-analysisQ37775403
Traditional cardiovascular risk factors in rheumatoid arthritis: a meta-analysisQ37790040
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HLA-DRB1 and persistent chronic inflammation contribute to cardiovascular events and cardiovascular mortality in patients with rheumatoid arthritisQ42610707
Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patientsQ42619505
Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohortsQ42621920
Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope allelesQ42674479
Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteinsQ44687984
HLA genes associated with rheumatoid arthritis. Identification of susceptibility alleles using specific oligonucleotide probesQ44999242
Design of the Women’s Health Initiative Clinical Trial and Observational StudyQ56483522
Persistent Chronic Inflammation Contributes to the Development of Cancer in Patients with Rheumatoid Arthritis from a Defined Population of Northwestern SpainQ57307121
Severe obesity, heart disease, and death among white, african american, and hispanic postmenopausal womenQ57616749
Association of anti-cyclic citrullinated peptide antibodies with clinical and radiological disease severity in rheumatoid arthritisQ58134996
Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritisQ58234987
Outcomes ascertainment and adjudication methods in the women's health initiativeQ79202519
Very recent onset rheumatoid arthritis: clinical and serological patient characteristics associated with radiographic progression over the first years of diseaseQ80087673
Cardiovascular death in rheumatoid arthritis: a population-based studyQ81484761
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectrheumatoid arthritisQ187255
cardiovascular disease in womenQ105047283
P304page(s)245-254
P577publication date2017-04-28
P1433published inAmerican Journal of EpidemiologyQ4744243
P1476titleHuman Leukocyte Antigen Shared Epitope and Inflammation, Cardiovascular Disease, Cancer, and Mortality Among Postmenopausal Women in the Women's Health Initiative Rheumatoid Arthritis Study
P478volume186

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Q99638169Ethnic Disparities in Atherosclerotic Cardiovascular Disease Incidence and Prevalence Among Rheumatoid Arthritis Patients in the United States: a Systematic Reviewcites workP2860

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