The role of complement system in adipose tissue-related inflammation

scientific article published on 11 January 2016

The role of complement system in adipose tissue-related inflammation is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1021391886
P356DOI10.1007/S12026-015-8783-5
P698PubMed publication ID26754764
P5875ResearchGate publication ID290221991

P2093author name stringHorea Rus
Dallas Boodhoo
Sonia I Vlaicu
Alexandru Tatomir
Petru A Mircea
Stefan Vesa
P2860cites workDietary fat, abdominal obesity and smoking modulate the relationship between plasma complement component 3 concentrations and metabolic syndrome riskQ58037914
Detection of refolding conformers of complement protein C9 during insertion into membranesQ59046450
The Complement Abnormalities of LipodystrophyQ67433383
Immunoelectron-microscopic localization of the terminal C5b-9 complement complex in human atherosclerotic fibrous plaqueQ68888362
Ultrastructural localization of the membrane attack complex of complement in human renal tissuesQ68941322
Activation of the human terminal complement pathway in atherosclerosisQ69007426
Cells carrying C5b-9 complement complexes in human atherosclerotic wallQ69599663
Penetration of C8 and C9 in the C5b-9 complex across the erythrocyte membrane into the cytoplasmic spaceQ69856269
Immunohistochemical localization of the terminal C5b-9 complement complex in human aortic fibrous plaqueQ69924809
Increased level of the complement C3 protein in endogenous hypertriglyceridemiaQ70432122
Differentiation-induced production of ASP in human adipocytesQ70953487
Partial lipodystrophy and familial C3 deficiencyQ71142680
ASP stimulates glucose transport in cultured human adipocytesQ73294623
Local activation of the complement system in endoneurial microvessels of diabetic neuropathyQ73392993
Acylation stimulating protein stimulates insulin secretionQ73807086
C5b-9 terminal complement complex assembly on apoptotic cells in human arterial wall with atherosclerosisQ75317796
Sublytic C5b-9 induces proliferation of human aortic smooth muscle cells: role of mitogen activated protein kinase and phosphatidylinositol 3-kinaseQ77910759
Tyrosine phosphorylation and activation of Janus kinase 1 and STAT3 by sublytic C5b-9 complement complex in aortic endothelial cellsQ78007332
Acylation-stimulating Protein (ASP)/Complement C3adesArg Deficiency Results in Increased Energy Expenditure in MiceQ79291846
Cutaneous vascular deposition of C5b-9 and its role as a diagnostic adjunct in the setting of diabetes mellitus and porphyria cutanea tardaQ79452847
Levels of C3 in patients with severe, morbid and extreme obesity: its relationship to insulin resistance and different cardiovascular risk factorsQ79693121
Inflammatory proteins are related to total and abdominal adiposity in a healthy adolescent population: the AVENA StudyQ80229831
Mannose-binding lectin as a predictor of microalbuminuria in type 1 diabetes: an inception cohort studyQ81690810
Complement activation in diabetic ketoacidosis and its treatmentQ81799236
Plasma levels of mannan-binding lectin-associated serine proteases MASP-1 and MASP-2 are elevated in type 1 diabetes and correlate with glycaemic controlQ86383152
Serum mannose-binding lectin is a strong biomarker of diabetic retinopathy in chinese patients with diabetesQ86901917
Determination of reference intervals for serum complement C3 and C4 levels in Chinese Han ethnic malesQ87902579
RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phaseQ24291853
Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissueQ24292702
Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cellsQ24319998
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDLQ24669594
Membrane attack by complement: the assembly and biology of terminal complement complexesQ26997385
Molecular cloning and characterization of RGC-32, a novel gene induced by complement activation in oligodendrocytesQ28577330
Complement: a key system for immune surveillance and homeostasisQ29615484
An integrative genomics approach to infer causal associations between gene expression and diseaseQ29616385
Association of adipocyte genes with ASP expression: a microarray analysis of subcutaneous and omental adipose tissue in morbidly obese subjects.Q30384917
Complement factor H is expressed in adipose tissue in association with insulin resistanceQ33556525
Acylation stimulating protein (ASP), an adipocyte autocrine: new directionsQ33650742
Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosisQ33661588
Glycation of the complement regulatory protein CD59 is a novel biomarker for glucose handling in humansQ33682481
C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.Q33745559
Enhanced triglyceride clearance with intraperitoneal human acylation stimulating protein in C57BL/6 miceQ33873819
Adipsin is an adipokine that improves β cell function in diabetesQ34025740
Complement and its role in innate and adaptive immune responsesQ34088142
C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signalingQ34309482
Response gene to complement 32 (RGC-32) in endothelial cells is induced by glucose and helpful to maintain glucose homeostasis.Q34414925
Recombinant acylation stimulating protein administration to C3-/- mice increases insulin resistance via adipocyte inflammatory mechanismsQ34442404
Proteomic analysis in type 2 diabetes patients before and after a very low calorie diet reveals potential disease state and intervention specific biomarkersQ34557152
Alterations of the classic pathway of complement in adipose tissue of obesity and insulin resistanceQ34605296
RGC32 deficiency protects against high-fat diet-induced obesity and insulin resistance in miceQ34944257
Beyond lysis: how complement influences cell fate.Q35064278
Prevalence of metabolic syndrome and pre-metabolic syndrome in health professionals: LATINMETS Brazil studyQ35118002
Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.Q35133482
Response gene to complement 32 promotes vascular lesion formation through stimulation of smooth muscle cell proliferation and migrationQ35135052
Downregulation of complement C3 and C3aR expression in subcutaneous adipose tissue in obese womenQ35151778
Detection and quantification of the control proteins of the alternative pathway of complement in 3T3-L1 adipocytesQ42834039
Extensive deposits of complement C3d and C5b-9 in the choriocapillaris of eyes of patients with diabetic retinopathyQ43940024
Weight gain in relation to plasma levels of complement factor 3: results from a population-based cohort studyQ44015071
High expression of complement components in omental adipose tissue in obese men.Q44477341
Fasting acylation-stimulating protein is predictive of postprandial triglyceride clearanceQ44620944
Obesity-inducing diet promotes acylation stimulating protein resistance.Q44845545
Glycation inactivation of the complement regulatory protein CD59: a possible role in the pathogenesis of the vascular complications of human diabetesQ45077962
Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changesQ45739398
Complement-mediated chronic inflammation is associated with diabetic microvascular complicationQ46096929
Acylation stimulating protein but not complement C3 associates with metabolic syndrome components in Chinese children and adolescentsQ46355388
Adiponectin, acylation stimulating protein and complement C3 are altered in obesity in very young childrenQ46457269
Reduced body weight, adipose tissue, and leptin levels despite increased energy intake in female mice lacking acylation-stimulating proteinQ47245431
Complement activation in diabetic ketoacidosis brainsQ48640667
The complement inhibitor CD59 regulates insulin secretion by modulating exocytotic events.Q50802836
C3 and C4 are strongly related to adipose tissue variables and cardiovascular risk factors.Q51144592
Lifestyle changes followed by bariatric surgery lower inflammatory markers and the cardiovascular risk factors C3 and C4.Q51313938
Complement factor 3 is associated with insulin resistance and with incident type 2 diabetes over a 7-year follow-up period: the CODAM Study.Q51323653
Possible direct influence of complement 3 in decreasing insulin sensitvity in a cohort of overweight and obese subjects.Q51328491
Acylation stimulating protein (ASP) deficiency alters postprandial and adipose tissue metabolism in male mice.Q51559463
Fasting and postprandial plasma concentrations of acylation-stimulation protein (ASP) in lean and obese Pima Indians compared to Caucasians.Q51560677
Mice lacking acylation stimulating protein (ASP) have delayed postprandial triglyceride clearance.Q51561024
Plasma acylation-stimulating protein in coronary artery disease.Q51574574
The membrane attack mechanism of complement: photolabeling reveals insertion of terminal proteins into target membraneQ52736479
C5b-9-induced endothelial cell proliferation and migration are dependent on Akt inactivation of forkhead transcription factor FOXO1.Q53624797
Quantitative evaluation of the terminal C5b-9 complement complex by ELISA in human atherosclerotic arteries.Q53811496
The membrane attack complex of complement: C5b-8 complex as accelerator of C9 polymerization.Q54458101
Effect of acylation stimulating protein on the triacylglycerol synthetic pathway of human adipose tissue.Q55051842
Reduced adipose tissue triglyceride synthesis and increased muscle fatty acid oxidation in C5L2 knockout miceQ55162949
Serum C3 is a stronger inflammatory marker of insulin resistance than C-reactive protein, leukocyte count, and erythrocyte sedimentation rate: comparison study in an elderly populationQ56994562
Low-grade inflammation and insulin resistance independently explain substantial parts of the association between body fat and serum C3: The CODAM studyQ57415486
The TLQP-21 peptide activates the G-protein-coupled receptor C3aR1 via a folding-upon-binding mechanismQ35159111
Elevated serum levels of mannose-binding lectin and diabetic nephropathy in type 2 diabetesQ35213862
Role of complement and complement regulatory proteins in the complications of diabetesQ35657115
The role of complement activation in atherosclerosisQ35838666
Elevated properdin and enhanced complement activation in first-degree relatives of South Asian subjects with type 2 diabetesQ35841122
Complement activation and prognosis in patients with type 2 diabetes and myocardial infarction: a report from the DIGAMI 2 trial.Q35841134
Polymerization of the ninth component of complement (C9): formation of poly(C9) with a tubular ultrastructure resembling the membrane attack complex of complementQ36278524
Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cellsQ36362882
Up-regulation of the complement system in subcutaneous adipocytes from nonobese, hypertriglyceridemic subjects is associated with adipocyte insulin resistanceQ36442478
Clinical analysis of selected complement-derived molecules in human adipose tissueQ36604268
Molecular basis for a link between complement and the vascular complications of diabetesQ36977373
Response gene to complement 32 deficiency causes impaired placental angiogenesis in mice.Q37104156
Role of response gene to complement 32 in diseasesQ37121718
The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistanceQ37280702
Mice lacking C1q are protected from high fat diet-induced hepatic insulin resistance and impaired glucose homeostasisQ37311913
Adipokines and the immune system: an adipocentric view.Q37331640
RGC-32 is a novel regulator of the T-lymphocyte cell cycleQ37334611
Plasma Levels of Acylation-Stimulating Protein Are Strongly Predicted by Waist/Hip Ratio and Correlate with Decreased LDL Size in Men.Q37515367
Innate immunity and adipose tissue biologyQ37740579
Acylation stimulating protein: a female lipogenic factor?Q37846807
Complement C3 and cleavage products in cardiometabolic riskQ37854933
Role of C5b-9 complement complex and response gene to complement-32 (RGC-32) in cancerQ38068141
The role of the complement system in metabolic organs and metabolic diseasesQ38107674
Adipose tissue inflammation: feeding the development of type 2 diabetes mellitusQ38118441
Visceral adipose tissue as a source of inflammation and promoter of atherosclerosisQ38188132
Relationships among acylation stimulating protein, adiponectin and complement C3 in lean vs obese type 2 diabetesQ38318585
The role of complement factor C3 in lipid metabolismQ38369254
The role of complement activation in atherogenesis: the first 40 yearsQ38532361
Beta cell dysfunction and insulin resistanceQ39325879
A new effector of lipid metabolism: complement factor properdinQ39386373
Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cellsQ40304477
Determinants and definition of abdominal obesity as related to risk of diabetes, metabolic syndrome and coronary disease in Turkish men: a prospective cohort studyQ40327679
Complement C3 is a risk factor for the development of diabetes: a population-based cohort study.Q40450370
Association of serum C3 levels with the risk of myocardial infarction.Q40989911
Complement-mediated adipocyte lysis by nephritic factor seraQ41980848
Mechanisms involved in the regulation of free fatty acid release from isolated human fat cells by acylation-stimulating protein and insulinQ42473514
Complement C3: an emerging risk factor in cardiometabolic diseaseQ42594073
The C3a anaphylatoxin receptor is a key mediator of insulin resistance and functions by modulating adipose tissue macrophage infiltration and activationQ42796229
Adipsin and an endogenous pathway of complement from adipose cells.Q42818598
P433issue3
P921main subjectinflammationQ101991
P304page(s)653-664
P577publication date2016-01-11
P1433published inImmunologic ResearchQ15754981
P1476titleThe role of complement system in adipose tissue-related inflammation
P478volume64

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cites work (P2860)
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