| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1038585164 |
| P356 | DOI | 10.1038/NATURE17042 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/nature17042 |
| P698 | PubMed publication ID | 26791724 |
| P2093 | author name string | Eric D Brown | |
| Gerard D Wright | |||
| P2860 | cites work | Antibiotic resistance is prevalent in an isolated cave microbiome | Q21089884 |
| Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection | Q22122301 | ||
| A new antibiotic kills pathogens without detectable resistance | Q24091299 | ||
| Essential Bacillus subtilis genes | Q24681292 | ||
| Privileged structures: efficient chemical "navigators" toward unexplored biologically relevant chemical spaces | Q26995668 | ||
| Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa | Q27666204 | ||
| Antibiotic resistance is ancient | Q27672681 | ||
| A structural basis for streptomycin-induced misreading of the genetic code | Q27675910 | ||
| Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics | Q27678160 | ||
| Whole-genome random sequencing and assembly of Haemophilus influenzae Rd | Q27860765 | ||
| Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings | Q27861111 | ||
| Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry | Q27861116 | ||
| The genetic landscape of a cell | Q28131628 | ||
| Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways | Q28478052 | ||
| Non-traditional antibacterial screening approaches for the identification of novel inhibitors of the glyoxylate shunt in gram-negative pathogens | Q28484292 | ||
| Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity | Q28542505 | ||
| The antibiotic resistome: the nexus of chemical and genetic diversity | Q29544028 | ||
| Drugs for bad bugs: confronting the challenges of antibacterial discovery | Q29547723 | ||
| Comprehensive transposon mutant library of Pseudomonas aeruginosa | Q29614861 | ||
| Prokaryotic toxin-antitoxin stress response loci | Q29615335 | ||
| Antibiotics for emerging pathogens | Q29615377 | ||
| Interaction network containing conserved and essential protein complexes in Escherichia coli | Q29615776 | ||
| Origins and evolution of antibiotic resistance | Q29617791 | ||
| Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. | Q30352594 | ||
| Essential genome of Pseudomonas aeruginosa in cystic fibrosis sputum | Q30636019 | ||
| Bioactive microbial metabolites | Q31157729 | ||
| Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration? | Q33231839 | ||
| The neglected intrinsic resistome of bacterial pathogens | Q33320525 | ||
| The discovery of antibacterial agents using diversity-oriented synthesis | Q33469588 | ||
| Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus | Q33494641 | ||
| Network visualization and analysis of gene expression data using BioLayout Express(3D). | Q33508084 | ||
| Antibiotics induce redox-related physiological alterations as part of their lethality. | Q33665248 | ||
| Specialized transduction designed for precise high-throughput unmarked deletions in Mycobacterium tuberculosis. | Q33724924 | ||
| Antibiotic sensitivity profiles determined with an Escherichia coli gene knockout collection: generating an antibiotic bar code | Q33768891 | ||
| Phenotypic landscape of a bacterial cell | Q33780274 | ||
| Challenges of antibacterial discovery | Q33793074 | ||
| The shared antibiotic resistome of soil bacteria and human pathogens | Q33804392 | ||
| The future of antibiotics | Q33821520 | ||
| Bacterial phylogeny structures soil resistomes across habitats | Q33837847 | ||
| Pay dirt: the story of streptomycin. Part I. From Waksman to Waksman | Q34051761 | ||
| A genome-wide strategy for the identification of essential genes in Staphylococcus aureus | Q34123679 | ||
| Persistence of antibiotic resistance in bacterial populations. | Q34195622 | ||
| Classics in infectious diseases: on the antibacterial action of cultures of a penicillium, with special reference to their use in the isolation of B. influenzae by Alexander Fleming, Reprinted from the British Journal of Experimental Pathology [...] | Q34275053 | ||
| A forward chemical screen identifies antibiotic adjuvants in Escherichia coli | Q34304387 | ||
| Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms. | Q34347048 | ||
| The scourge of antibiotic resistance: the important role of the environment | Q34347746 | ||
| An environmental bacterial taxon with a large and distinct metabolic repertoire | Q34400837 | ||
| Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance | Q34426513 | ||
| Beta-lactam antibiotics induce a lethal malfunctioning of the bacterial cell wall synthesis machinery | Q34645039 | ||
| Design, diversity-oriented synthesis and structure activity relationship studies of quinolinyl heterocycles as antimycobacterial agents | Q35031592 | ||
| Novel approaches are needed to develop tomorrow's antibacterial therapies | Q35140751 | ||
| Systematic discovery of multicomponent therapeutics | Q35147474 | ||
| The soil resistome: a critical review on antibiotic resistance origins, ecology and dissemination potential in telluric bacteria. | Q35305715 | ||
| New targets and screening approaches in antimicrobial drug discovery | Q36034635 | ||
| Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase | Q36055552 | ||
| Lessons from signature-tagged mutagenesis on the infectious mechanisms of pathogenic bacteria | Q36231150 | ||
| Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents | Q37145603 | ||
| Daptomycin: from the mountain to the clinic, with essential help from Francis Tally, MD. | Q37672614 | ||
| Intrinsic antibiotic resistance: mechanisms, origins, challenges and solutions | Q38090174 | ||
| Ribosome-targeting antibiotics and mechanisms of bacterial resistance. | Q38171225 | ||
| Unraveling the physiological complexities of antibiotic lethality. | Q38253949 | ||
| The antibiotic resistome: what's new? | Q38256461 | ||
| Unconventional screening approaches for antibiotic discovery | Q38534653 | ||
| Bioinformatics of antimicrobial resistance in the age of molecular epidemiology | Q38560571 | ||
| Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation | Q38571499 | ||
| Sampling the antibiotic resistome | Q40357052 | ||
| Simultaneous identification of bacterial virulence genes by negative selection. | Q40682435 | ||
| Experimental and computational assessment of conditionally essential genes in Escherichia coli | Q41063583 | ||
| Lesions in teichoic acid biosynthesis in Staphylococcus aureus lead to a lethal gain of function in the otherwise dispensable pathway | Q41670400 | ||
| Is the GAIN Act a turning point in new antibiotic discovery? | Q42268705 | ||
| Inhibition of WTA synthesis blocks the cooperative action of PBPs and sensitizes MRSA to β-lactams. | Q42932637 | ||
| Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production | Q43226870 | ||
| Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting. | Q43270534 | ||
| Impact of high-throughput screening in biomedical research | Q45352809 | ||
| Probing teichoic acid genetics with bioactive molecules reveals new interactions among diverse processes in bacterial cell wall biogenesis. | Q45992133 | ||
| Mining the microbial dark matter | Q46713549 | ||
| Antibiotics: Recover the lost art of drug discovery. | Q48438044 | ||
| An enzyme from bacteria able to destroy penicillin. 1940. | Q52397925 | ||
| ESKAPEing the labyrinth of antibacterial discovery. | Q53834237 | ||
| An Enzyme from Bacteria able to Destroy Penicillin | Q54138191 | ||
| Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy | Q57001135 | ||
| Physicochemical properties of antibacterial compounds: implications for drug discovery | Q80662325 | ||
| Are essential genes really essential? | Q84573635 | ||
| OPT-80, a macrocyclic antimicrobial agent for the treatment of Clostridium difficile infections: a review | Q94693976 | ||
| P433 | issue | 7586 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | drug discovery | Q1418791 |
| P304 | page(s) | 336-343 | |
| P577 | publication date | 2016-01-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Antibacterial drug discovery in the resistance era. | |
| P478 | volume | 529 |
| Q40495313 | 5-Alkyloxytryptamines are membrane-targeting, broad-spectrum antibiotics |
| Q55171212 | A 2-transcript host cell signature distinguishes viral from bacterial diarrhea and it is influenced by the severity of symptoms. |
| Q64905492 | A Critical Review on Selected External Physical Cues and Modulation of Cell Behavior: Magnetic Nanoparticles, Non-thermal Plasma and Lasers. |
| Q40208622 | A Highly Potent Class of Halogenated Phenazine Antibacterial and Biofilm-Eradicating Agents Accessed Through a Modular Wohl-Aue Synthesis |
| Q55239147 | A Rapid Growth-Independent Antibiotic Resistance Detection Test by SYBR Green/Propidium Iodide Viability Assay. |
| Q89307752 | A Unified Strategy for the Syntheses of the Isoquinolinium Alkaloids Berberine, Coptisine, and Jatrorrhizine |
| Q40742571 | A Vancomycin Derivative with a Pyrophosphate-Binding Group: A Strategy to Combat Vancomycin-Resistant Bacteria |
| Q99630504 | A boronic acid-functionalized phthalocyanine with an aggregation-enhanced photodynamic effect for combating antibiotic-resistant bacteria |
| Q36992106 | A cross-metathesis approach to novel pantothenamide derivatives |
| Q60907792 | A diversity-oriented rhodamine library for wide-spectrum bactericidal agents with low inducible resistance against resistant pathogens |
| Q60909484 | A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium |
| Q92284621 | A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria |
| Q77704224 | A new antibiotic selectively kills Gram-negative pathogens |
| Q93170718 | A screening platform to monitor RNA processing and protein-RNA interactions in ribonuclease P uncovers a small molecule inhibitor |
| Q64980344 | A symbiotic supramolecular approach to the design of novel amphiphiles with antibacterial properties against MSRA. |
| Q46794368 | Accelerating the discovery of antibacterial compounds using pathway-directed whole cell screening |
| Q40396743 | Activation of the glmS Ribozyme Confers Bacterial Growth Inhibition |
| Q92993278 | Additive Bayesian networks for antimicrobial resistance and potential risk factors in non-typhoidal Salmonella isolates from layer hens in Uganda |
| Q90662570 | Adevonin, a novel synthetic antimicrobial peptide designed from the Adenanthera pavonina trypsin inhibitor (ApTI) sequence |
| Q60949764 | Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response |
| Q89967482 | Amphiphilic Cationic Macromolecules Highly Effective Against Multi-Drug Resistant Gram-Positive Bacteria and Fungi With No Detectable Resistance |
| Q38840796 | An update on the use of C. elegans for preclinical drug discovery: screening and identifying anti-infective drugs |
| Q58585272 | Anti-MRSA Sesquiterpenes from the Semi-Mangrove Plant A. Gray |
| Q90988745 | AntiBac-Pred: A Web Application for Predicting Antibacterial Activity of Chemical Compounds |
| Q58641877 | Antibacterial Activity of Teixobactin Derivatives on Clinically Relevant Bacterial Isolates |
| Q30303549 | Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase |
| Q64081361 | Antibacterial and anticancer activities of orphan biosynthetic gene clusters from Atlantis II Red Sea brine pool |
| Q94551842 | Antibacterial, Antifungal, Antiviral, and Anthelmintic Activities of Medicinal Plants of Nepal Selected Based on Ethnobotanical Evidence |
| Q90332490 | Antibiotic Resistance: Current Perspectives |
| Q47429185 | Antibiotic efficacy-context matters |
| Q100428022 | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex |
| Q40542863 | Antibiotic resistance in Burkholderia species |
| Q45975273 | Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. |
| Q92633370 | Antibody Conjugates-Recent Advances and Future Innovations |
| Q91613804 | Antimicrobial Activities of Dictyostelium Differentiation-Inducing Factors and Their Derivatives |
| Q92227017 | Antimicrobial Activity of Substituted Benzopentathiepin-6-amines |
| Q90666032 | Antimicrobial activity of RP-1 peptide conjugate with ferrocene group |
| Q40202244 | Antimicrobial peptide-inspired NH125 analogues: bacterial and fungal biofilm-eradicating agents and rapid killers of MRSA persisters. |
| Q39016864 | Antimicrobial resistance surveillance in the genomic age. |
| Q64120548 | Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison |
| Q105148122 | Asperteramide A, an Unusual N -Phenyl-Carbamic Acid Methyl Ester Trimer Isolated from the Coral-Derived Fungus Aspergillus Terreus |
| Q91676120 | Bacterial Metabolism and Antibiotic Efficacy |
| Q38847719 | Bacterial disease management: challenges, experience, innovation and future prospects: Challenges in Bacterial Molecular Plant Pathology. |
| Q38964523 | Bacterial fatty acid metabolism in modern antibiotic discovery |
| Q39023951 | Bacterial proteases, untapped antimicrobial drug targets |
| Q50884240 | Bacteriophages or bacteriovores - that is the question: variations on the theme of eating Stenotrophomonas maltophilia. |
| Q44606676 | Beauvericin counteracted multi-drug resistant Candida albicans by blocking ABC transporters. |
| Q54217509 | Behavioral Economics Interventions to Improve Outpatient Antibiotic Prescribing for Acute Respiratory Infections: a Cost-Effectiveness Analysis. |
| Q28071846 | Beyond Traditional Antimicrobials: A Caenorhabditis elegans Model for Discovery of Novel Anti-infectives |
| Q64058555 | Brevibacillus laterosporus strains BGSP7, BGSP9 and BGSP11 isolated from silage produce broad spectrum multi-antimicrobials |
| Q28584458 | CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database |
| Q58739098 | Cathelicidins: Immunomodulatory Antimicrobials |
| Q61800934 | Cationic Amphipathic Triazines with Potent Anti-bacterial, Anti-inflammatory and Anti-atopic Dermatitis Properties |
| Q92839359 | Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action |
| Q97886972 | Chemical genetics in drug discovery |
| Q62686090 | Chemo-Diversification of Plant Extracts Using a Generic Bromination Reaction and Monitoring by Metabolite Profiling |
| Q61453596 | Chemogenomic model identifies synergistic drug combinations robust to the pathogen microenvironment |
| Q92678654 | Chimeric LuxR Transcription Factors Rewire Natural Product Regulation |
| Q26748249 | Chloramphenicol Derivatives as Antibacterial and Anticancer Agents: Historic Problems and Current Solutions |
| Q66459589 | Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria |
| Q91287755 | Coagulation factors: a novel class of endogenous host antimicrobial proteins against drug-resistant gram-negative bacteria |
| Q109715932 | Combination of Pseudo-LC-NMR and HRMS/MS-Based Molecular Networking for the Rapid Identification of Antimicrobial Metabolites From Fusarium petroliphilum |
| Q89510084 | Combinatorial Antimicrobial Susceptibility Testing Enabled by Non-Contact Printing |
| Q51160004 | Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. |
| Q37705303 | Combinatorial strategies for combating invasive fungal infections. |
| Q47946171 | Comparative analysis of internalisation, haemolytic, cytotoxic and antibacterial effect of membrane-active cationic peptides: aspects of experimental setup |
| Q46304940 | Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes |
| Q91904647 | Comparison of the Wild-Type Obligate Methylotrophic Bacterium Methylophilus quaylei and its Isogenic Streptomycin-Resistant Mutant via Metal Nanoparticle Generation |
| Q103028703 | Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences |
| Q54114106 | Computer simulations of the signalling network in FLT3 +-acute myeloid leukaemia - indications for an optimal dosage of inhibitors against FLT3 and CDK6. |
| Q38803671 | Contemporary challenges and opportunities in the diagnosis and outbreak detection of multidrug-resistant infectious disease |
| Q28071667 | Convergent biosynthetic pathways to β-lactam antibiotics |
| Q47214307 | Coupling next-generation sequencing to dominant positive screens for finding antibiotic cellular targets and resistance mechanisms in Escherichia coli |
| Q38661567 | Curative Treatment of Severe Gram-Negative Bacterial Infections by a New Class of Antibiotics Targeting LpxC. |
| Q59197547 | Current and Emerging Approaches to Engineer Antibacterial and Antifouling Electrospun Nanofibers |
| Q95628507 | Customised structural, optical and antibacterial characteristics of cinnamon nanoclusters produced inside organic solvent using 532 nm Q-switched Nd:YAG-pulse laser ablation |
| Q92324699 | De novo synthesis, structural assignment and biological evaluation of pseudopaline, a metallophore produced by Pseudomonas aeruginosa |
| Q89529445 | Deep Hypersaline Anoxic Basins as Untapped Reservoir of Polyextremophilic Prokaryotes of Biotechnological Interest |
| Q92557987 | Deep2Full: Evaluating strategies for selecting the minimal mutational experiments for optimal computational predictions of deep mutational scan outcomes |
| Q64265252 | Defining the core essential genome of |
| Q61449406 | Desferrioxamine:gallium-pluronic micelles increase outer membrane permeability and potentiate antibiotic activity against Pseudomonas aeruginosa |
| Q90193307 | Design, Synthesis, and Anti-Bacterial Evaluation of Triazolyl-Pterostilbene Derivatives |
| Q89618193 | Design, Synthesis, and Biochemical Characterization of Non-Native Antagonists of the Pseudomonas aeruginosa Quorum Sensing Receptor LasR with Nanomolar IC50 Values |
| Q88445687 | Design, solid-phase synthesis and evaluation of enterobactin analogs for iron delivery into the human pathogen Campylobacter jejuni |
| Q52577886 | Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial agents. |
| Q42718330 | Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes. |
| Q90133843 | Design, synthesis, and discovery of novel oxindoles bearing 3-heterocycles as species-specific and combinatorial agents in eradicating Staphylococcus species |
| Q40093569 | Development and use of personalized bacteriophage-based therapeutic cocktails to treat a patient with a disseminated resistant Acinetobacter baumannii infection |
| Q91665007 | Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E |
| Q92668948 | Development of a nebramine-cyclam conjugate as an antibacterial adjuvant to potentiate β-lactam antibiotics against multidrug-resistant P. aeruginosa |
| Q61814614 | Dictyostelium: An Important Source of Structural and Functional Diversity in Drug Discovery |
| Q46032234 | Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1. |
| Q92712303 | Disarming Pseudomonas aeruginosa Virulence by the Inhibitory Action of 1,10-Phenanthroline-5,6-Dione-Based Compounds: Elastase B (LasB) as a Chemotherapeutic Target |
| Q57023536 | Discovering a new class of antifungal agents that selectively inhibits microbial carbonic anhydrases |
| Q88797868 | Discovery and Development of 8-Substituted Cycloberberine Derivatives as Novel Antibacterial Agents against MRSA |
| Q58705939 | Discovery of (phenylureido)piperidinyl benzamides as prospective inhibitors of bacterial autolysin E from Staphylococcus aureus |
| Q92700100 | Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection |
| Q48092995 | Discovery of antimicrobial compounds targeting bacterial type FAD synthetases. |
| Q48180953 | Discovery of novel bacterial topoisomerase I inhibitors by use of in silico docking and in vitro assays. |
| Q64882215 | Discovery of potential antifungal triazoles: design, synthesis, biological evaluation, and preliminary antifungal mechanism exploration. |
| Q93345577 | Discovery, properties, and biosynthesis of pseudouridimycin, an antibacterial nucleoside-analog inhibitor of bacterial RNA polymerase |
| Q95338047 | Divergent synthesis of novel cylindrocyclophanes that inhibit methicillin-resistant Staphylococcus aureus (MRSA) |
| Q62673364 | Drug combinations: a strategy to extend the life of antibiotics in the 21st century |
| Q88806413 | Drug development: Locking down metabolism |
| Q40259823 | Dual function of tropodithietic acid as antibiotic and signaling molecule in global gene regulation of the probiotic bacterium Phaeobacter inhibens |
| Q100476544 | Effect of Secondary Structure and Side Chain Length of Hydrophobic Amino Acid Residues on the Antimicrobial Activity and Toxicity of 14 Residue Long de novo AMPs |
| Q97528564 | Effect of bacterial nanocellulose binding on the bactericidal activity of bovine lactoferrin |
| Q60343704 | Effect of the duration of antimicrobial exposure on the development of antimicrobial resistance (AMR) for macrolide antibiotics: protocol for a systematic review with a network meta-analysis |
| Q55281938 | Effects of Achyrocline satureioides Inflorescence Extracts against Pathogenic Intestinal Bacteria: Chemical Characterization, In Vitro Tests, and In Vivo Evaluation. |
| Q96639848 | Efficient self-assembly of heterometallic triangular necklace with strong antibacterial activity |
| Q91741533 | Electrochemical Immunosensors for Antibiotic Detection |
| Q91839870 | Elucidating the Catalytic Power of Glutamate Racemase by Investigating a Series of Covalent Inhibitors |
| Q47443193 | Emerging and evolving concepts in gene essentiality. |
| Q47741040 | Emerging mechanisms of antimicrobial resistance in bacteria and fungi: advances in the era of genomics |
| Q39042753 | Enterosalivary nitrate metabolism and the microbiome: Intersection of microbial metabolism, nitric oxide and diet in cardiac and pulmonary vascular health |
| Q36241590 | EpideMiology and control measures of outBreaks due to Antibiotic-Resistant orGanisms in EurOpe (EMBARGO): a systematic review protocol |
| Q58769218 | Epigenetic modulator UVI5008 inhibits MRSA by interfering with bacterial gyrase |
| Q91650255 | Essential Metabolic Routes as a Way to ESKAPE From Antibiotic Resistance |
| Q48371459 | Essential Two-Component Systems Regulating Cell Envelope Functions: Opportunities for Novel Antibiotic Therapies. |
| Q53762102 | Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity. |
| Q64263039 | Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligases |
| Q92238786 | Evolving Antibiotics against Resistance: a Potential Platform for Natural Product Development? |
| Q50221694 | Expanding the potential of NAI-107 for treating serious ESKAPE pathogens: synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells. |
| Q38852919 | Exploiting the porin pathway for polar compound delivery into Gram-negative bacteria. |
| Q38823110 | Exploring Intein Inhibition by Platinum Compounds as an Antimicrobial Strategy |
| Q55477355 | Expression of the Shrimp wap gene in Drosophila elicits defense responses and protease inhibitory activity. |
| Q47586901 | Factor H-IgG Chimeric Proteins as a Therapeutic Approach against the Gram-Positive Bacterial Pathogen Streptococcus pyogenes |
| Q48202020 | Fluoro-Carba-Sugars are Glycomimetic Activators of the glmS Ribozyme |
| Q41600562 | Fostering research into antimicrobial resistance in India |
| Q64095705 | Fragment-based screening identifies inhibitors of ATPase activity and of hexamer formation of Cagα from the Helicobacter pylori type IV secretion system |
| Q47095102 | Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101. |
| Q48322890 | Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme. |
| Q38838727 | From bench to bed and back again: phage therapy of childhood Escherichia coli diarrhea |
| Q59794850 | Full-length title: NRPPUR database search and in vitro analysis identify an NRPS-PKS biosynthetic gene cluster with a potential antibiotic effect |
| Q53696671 | Functionalization of β-lactam antibiotic on lysozyme capped gold nanoclusters retrogress MRSA and its persisters following awakening. |
| Q97684623 | Generation of Stilbene Antimicrobials against Multiresistant Strains of Staphylococcus aureus through Biotransformation by the Enzymatic Secretome of Botrytis cinerea |
| Q39063044 | Genetic Regulation of Virulence and Antibiotic Resistance in Acinetobacter baumannii |
| Q37712935 | Genetic engineering of a temperate phage-based delivery system for CRISPR/Cas9 antimicrobials against Staphylococcus aureus |
| Q60017695 | Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli |
| Q92576877 | Genomic and Metagenomic Approaches for Predictive Surveillance of Emerging Pathogens and Antibiotic Resistance |
| Q38987535 | Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes |
| Q45073974 | Global landscape of cell envelope protein complexes in Escherichia coli. |
| Q46263582 | Global phylogenetic analysis of Escherichia coli and plasmids carrying the mcr-1 gene indicates bacterial diversity but plasmid restriction |
| Q90040964 | High Stability Thiol-Coated Gold Nanostars Monolayers with Photo-Thermal Antibacterial Activity and Wettability Control |
| Q58569022 | High-Throughput Screening of Biodiversity for Antibiotic Discovery |
| Q96609310 | Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance |
| Q47093744 | Host Antimicrobial Peptides: The Promise of New Treatment Strategies against Tuberculosis |
| Q39045096 | Human lung ex vivo infection models. |
| Q91782238 | Hydrogels Embedded With Melittin and Tobramycin Are Effective Against Pseudomonas aeruginosa Biofilms in an Animal Wound Model |
| Q89766030 | Hypermutator Pseudomonas aeruginosa exploits multiple genetic pathways to develop multidrug resistance during long-term infections in the airways of cystic fibrosis patients |
| Q92459815 | Identification of Primary Antimicrobial Resistance Drivers in Agricultural Nontyphoidal Salmonella enterica Serovars by Using Machine Learning |
| Q91897802 | Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus |
| Q64994909 | Identification of anti-Gram-negative bacteria agents targeting the interaction between ribosomal proteins L12 and L10. |
| Q40067898 | Identification of the Biosynthesis Gene Cluster for the Novel Lantibiotic Paenilan from Paenibacillus polymyxa E681 and Characterization of its Product |
| Q43850749 | Imaging the Antistaphylococcal Activity of CATH-2: Mechanism of Attack and Regulation of Inflammatory Response. |
| Q89864975 | Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development |
| Q47131617 | Importance of Core Genome Functions for an Extreme Antibiotic Resistance Trait |
| Q46237661 | In Situ Disinfection through Photoinspired Radical Oxygen Species Storage and Thermal-Triggered Release from Black Phosphorous with Strengthened Chemical Stability. |
| Q50855186 | In Vitro Activities of LCB 01-0648, a Novel Oxazolidinone, against Gram-Positive Bacteria. |
| Q49552573 | In Vivo Activity of LCB 01-0699, a Prodrug of LCB 01-0648, against Staphylococcus aureus. |
| Q45976566 | In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA). |
| Q47142806 | Increasing the permeability of Escherichia coli using MAC13243. |
| Q90713703 | Inducible Antibacterial Activity in the Bacillales by Triphenyl Tetrazolium Chloride |
| Q40122828 | Infection therapy: the problem of drug resistance - and possible solutions |
| Q57166222 | Inflatable Penile Prostheses Implantation: Does Antibiotic Exposure Matter? |
| Q90225928 | Inhibition of Pore-Forming Proteins |
| Q64955891 | Insights into Red Sea Brine Pool Specialized Metabolism Gene Clusters Encoding Potential Metabolites for Biotechnological Applications and Extremophile Survival. |
| Q58794879 | Insights into the development of chemical probes for RNA |
| Q41565293 | Intertidal marine sediment harbours Actinobacteria with promising bioactive and biosynthetic potential |
| Q42351008 | Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth. |
| Q38605728 | Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel. |
| Q47941828 | Ligand design for riboswitches, an emerging target class for novel antibiotics |
| Q64068066 | Machine learning-powered antibiotics phenotypic drug discovery |
| Q52659220 | Magnolol restores the activity of meropenem against NDM-1-producing Escherichia coli by inhibiting the activity of metallo-beta-lactamase. |
| Q52842326 | Making the Mute Speak Again. |
| Q57486520 | Mechanistic Pathways for Peptidoglycan O-Acetylation and De-O-Acetylation |
| Q91705959 | Metabolomics-Driven Exploration of the Chemical Drug Space to Predict Combination Antimicrobial Therapies |
| Q58600286 | Metallo-polyelectrolytes as a class of ionic macromolecules for functional materials |
| Q47215889 | Microbial protein targets: towards understanding and intervention |
| Q90975671 | Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens |
| Q57149935 | Mining Actinomycetes for Novel Antibiotics in the Omics Era: Are We Ready to Exploit This New Paradigm? |
| Q59804929 | Modification Targeting the “Rana Box” Motif of a Novel Nigrocin Peptide From Hylarana latouchii Enhances and Broadens Its Potency Against Multiple Bacteria |
| Q40998796 | Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release. |
| Q64056406 | Molecular Fingerprints for a Novel Enzyme Family in with Glucosamine Kinase Activity |
| Q91795964 | Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant Klebsiella pneumoniae to Meropenem |
| Q61455372 | Molecules that Inhibit Bacterial Resistance Enzymes |
| Q38755880 | Multicomponent Petasis-borono Mannich Preparation of Alkylaminophenols and Antimicrobial Activity Studies |
| Q36349644 | Multidrug-resistant bacteria compensate for the epistasis between resistances. |
| Q66680689 | Mutagenesis of DsbAss is Crucial for the Signal Recognition Particle Mechanism in : Insights from Molecular Dynamics Simulations |
| Q93051838 | Mygalin: An Acylpolyamine With Bactericidal Activity |
| Q53779399 | N-Heterocyclic molecule-capped gold nanoparticles as effective antibiotics against multi-drug resistant bacteria. |
| Q46298691 | Na+-NQR (Na+-translocating NADH:ubiquinone oxidoreductase) as a novel target for antibiotics |
| Q99711055 | Naphthoquinone-derivative as a synthetic compound to overcome the antibiotic resistance of methicillin-resistant S. aureus |
| Q38889355 | New Found Hope for Antibiotic Discovery: Lipid II Inhibitors |
| Q92500593 | New Perspectives on Galleria mellonella Larvae as a Host Model Using Riemerella anatipestifer as a Proof of Concept |
| Q39230397 | Next-generation approaches to understand and combat the antibiotic resistome. |
| Q54203030 | Nitrothiophene carboxamides, a novel narrow spectrum antibacterial series: Mechanism of action and Efficacy. |
| Q91816187 | Novel 5-substituted derivatives of 2'-deoxy-6-azauridine with antibacterial activity |
| Q47233183 | Novel Naphthalimide Aminothiazoles as Potential Multitargeting Antimicrobial Agents |
| Q91724807 | Novel tool to quantify cell wall porosity relates wall structure to cell growth and drug uptake |
| Q40189627 | Opportunities for natural products in 21st century antibiotic discovery |
| Q100416071 | Over-activation of a nonessential bacterial protease DegP as an antibiotic strategy |
| Q92277520 | Patient Awareness of Antimicrobial Resistance and Antibiotic Use in Acne Vulgaris |
| Q40306876 | Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance. |
| Q92025799 | Peptidoglycan O-Acetylation as a Virulence Factor: Its Effect on Lysozyme in the Innate Immune System |
| Q40192107 | Peripheral modifications of [Ψ[CH2NH]Tpg4]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics |
| Q67311480 | Phenotypic plasticity of Escherichia coli upon exposure to physical stress induced by ZnO nanorods. |
| Q96136244 | Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential |
| Q46363573 | Piqueria trinervia as a source of metabolites against Giardia intestinalis |
| Q54205904 | Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. |
| Q91776949 | Polybasic peptide-levofloxacin conjugates potentiate fluoroquinolones and other classes of antibiotics against multidrug-resistant Gram-negative bacteria |
| Q52355112 | Potential Antimicrobial Isopropanol-Conjugated Carbazole Azoles as Dual Targeting Inhibitors of Enterococcus faecalis. |
| Q99545095 | Predicting the antimicrobial efficacy of hydrogen bonded, self-associating amphiphiles |
| Q41077819 | Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening |
| Q47722687 | Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7. |
| Q90293831 | Production of β-Lactamase Inhibitors by Streptomyces Species |
| Q64232292 | Promising Recent Strategies with Potential Clinical Translational Value to Combat Antibacterial Resistant Surge |
| Q59813277 | Protein-protein interactions in bacteria: a promising and challenging avenue towards the discovery of new antibiotics |
| Q57979412 | QM/MM simulations identify the determinants of catalytic activity differences between type II dehydroquinase enzymes |
| Q57139953 | Raman spectral signature reflects transcriptomic features of antibiotic resistance in |
| Q92702323 | Rapid kill assessment of an N-arylated NH125 analogue against drug-resistant microorganisms |
| Q38651893 | Rapid screening for specific glycosylation and pathogen interactions on a 78 species avian egg white glycoprotein microarray |
| Q61817320 | Rationally designing antisense therapy to keep up with evolving bacterial resistance |
| Q38958278 | Recent Advances in the Rational Design and Optimization of Antibacterial Agents |
| Q97876123 | Recent advances in application of graphitic carbon nitride-based catalysts for degrading organic contaminants in water through advanced oxidation processes beyond photocatalysis: A critical review |
| Q49679615 | Recombinant yeast and human cells as screening tools to search for antibacterial agents targeting the transcription termination factor Rho. |
| Q48056331 | Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study. |
| Q58539530 | Refining the structure-activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms |
| Q92110440 | Repurposing Azithromycin and Rifampicin Against Gram-Negative Pathogens by Combination With Peptidomimetics |
| Q39078222 | Resistance diagnosis and the changing economics of antibiotic discovery |
| Q47578436 | Resource limitation prevents the emergence of drug resistance by intensifying within-host competition |
| Q42462291 | Ribosome Assembly as Antimicrobial Target |
| Q42283041 | Role for dithiolopyrrolones in disrupting bacterial metal homeostasis |
| Q58735057 | Rose Bengal-Mediated Photoinactivation of Multidrug Resistant Is Enhanced in the Presence of Antimicrobial Peptides |
| Q89941037 | Ruthenium based antimicrobial theranostics - using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus |
| Q89865193 | Safeguarding intestine cells against enteropathogenic Escherichia coli by intracellular protein reaction, a preventive antibacterial mechanism |
| Q91625796 | Secondary metabolites overproduction through transcriptional gene cluster refactoring |
| Q90013012 | Small Molecule Potentiation of Gram-Positive Selective Antibiotics against Acinetobacter baumannii |
| Q90609481 | Small antibacterial molecules highly active against drug-resistant Staphylococcus aureus |
| Q91025129 | Solution-phase total synthesis of teixobactin |
| Q56170738 | Species-specific activity of antibacterial drug combinations |
| Q91811652 | Structural Requirements of N-alpha-Mercaptoacetyl Dipeptide (NAMdP) Inhibitors of Pseudomonas Aeruginosa Virulence Factor LasB: 3D-QSAR, Molecular Docking, and Interaction Fingerprint Studies |
| Q89916856 | Structural approaches to pathway-specific antimicrobial agents |
| Q56029406 | Structural basis for dual-mode inhibition of the ABC transporter MsbA |
| Q62649637 | Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE |
| Q57805452 | Structure-guided disruption of the pseudopilus tip complex inhibits the Type II secretion in Pseudomonas aeruginosa |
| Q90228243 | Suppressing Antibacterial Resistance: Chemical Binding of Monolayer Quaternary Ammonium Salts to Polymethyl Methacrylate in an Aqueous Solution and its Clinical Efficacy |
| Q47603719 | Surface modification of valve metals using plasma electrolytic oxidation for antibacterial applications: A review |
| Q51144180 | Synergistic activity of cosecreted natural products from amoebae-associated bacteria. |
| Q89529685 | Synthesis and Antimicrobial Evaluation of Side-Chain Derivatives based on Eurotiumide A |
| Q90633128 | Synthesis and Biological Evaluation of Lipophilic Nucleoside Analogues as Inhibitors of Aminoacyl-tRNA Synthetases |
| Q64267593 | Synthesis and Biological Evaluation of Quinoline Derivatives as a Novel Class of Broad-Spectrum Antibacterial Agents |
| Q48175813 | Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors |
| Q102381501 | Synthesis and Structure Activity Relationship of Xenocoumacin 1 and Analogs as Inhibitors of Ribosomal Protein Synthesis |
| Q59327167 | Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus |
| Q92610846 | Synthesis of water-soluble prodrugs of 5-modified 2'-deoxyuridines and their antibacterial activity |
| Q92861769 | Targeting Antibiotic Resistance Genes Is a Better Approach to Block Acquisition of Antibiotic Resistance Than Blocking Conjugal Transfer by Recipient Cells: A Genome-Wide Screening in Escherichia coli |
| Q92485705 | Targeting S. mutans biofilms: a perspective on preventing dental caries |
| Q47134645 | Targeting the Bacterial Orisome in the Search for New Antibiotics |
| Q46745179 | Teixobactin as a scaffold for unlimited new antimicrobial peptides: SAR study. |
| Q91638638 | Testing a Human Antimicrobial RNase Chimera Against Bacterial Resistance |
| Q55082798 | Tetracycline-Inactivating Enzymes. |
| Q51748626 | The Antimicrobial Activity of a Carbon Monoxide Releasing Molecule (EBOR-CORM-1) Is Shaped by Intraspecific Variation within Pseudomonas aeruginosa Populations. |
| Q44872584 | The Challenge of Overcoming Antibiotic Resistance: An Adjuvant Approach? |
| Q33628014 | The Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor |
| Q52656083 | The Macromolecular Machines that Duplicate the Escherichia coli Chromosome as Targets for Drug Discovery. |
| Q90514316 | The Zebrafish as a Model Host for Invasive Fungal Infections |
| Q48120883 | The activity of the C4-dicarboxylic acid chemoreceptor of Pseudomonas aeruginosa is controlled by chemoattractants and antagonists. |
| Q39340690 | The advancement of multidimensional QSAR for novel drug discovery - where are we headed? |
| Q61805379 | The antimicrobial potential of Streptomyces from insect microbiomes |
| Q52656657 | The lantibiotic gallidermin acts bactericidal against Staphylococcus epidermidis and Staphylococcus aureus and antagonizes the bacteria-induced proinflammatory responses in dermal fibroblasts. |
| Q36260641 | The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase |
| Q36179001 | The polymyxin B-induced transcriptomic response of a clinical, multidrug-resistant Klebsiella pneumoniae involves multiple regulatory elements and intracellular targets |
| Q50071895 | The race for antimicrobials in the multidrug resistance era. |
| Q90059229 | Thermal proteome profiling for interrogating protein interactions |
| Q57910254 | Thermal proteome profiling in bacteria: probing protein state |
| Q90262316 | Thermo-responsive triple-function nanotransporter for efficient chemo-photothermal therapy of multidrug-resistant bacterial infection |
| Q37106265 | Thusin, a Novel Two-Component Lantibiotic with Potent Antimicrobial Activity against Several Gram-Positive Pathogens |
| Q38867326 | Toolbox for Antibiotics Discovery from Microorganisms |
| Q89494836 | Topical Therapeutic Efficacy of Ebselen Against Multidrug-Resistant Staphylococcus aureus LT-1 Targeting Thioredoxin Reductase |
| Q55398522 | Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics. |
| Q40125065 | Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2. |
| Q39258608 | Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues |
| Q39292881 | Total Synthesis and Functional Evaluation of Fourteen Derivatives of Lysocin E: Importance of Cationic, Hydrophobic, and Aromatic Moieties for Antibacterial Activity. |
| Q40538609 | Total Synthesis of Aspergillomarasmine A and Related Compounds: A Sulfamidate Approach Enables Exploration of Structure-Activity Relationships |
| Q91973738 | Translation-Targeting RiPPs and Where to Find Them |
| Q88376487 | Triclosan Is an Aminoglycoside Adjuvant for Eradication of Pseudomonas aeruginosa Biofilms |
| Q64890483 | Tridecaptin M, a New Variant Discovered in Mud Bacterium, Shows Activity against Colistin- and Extremely Drug-Resistant Enterobacteriaceae. |
| Q90108297 | Tryptoline-based benzothiazoles re-sensitize MRSA to β-lactam antibiotics |
| Q40625268 | Two Small RNAs Conserved in Enterobacteriaceae Provide Intrinsic Resistance to Antibiotics Targeting the Cell Wall Biosynthesis Enzyme Glucosamine-6-Phosphate Synthase |
| Q64327308 | Using Fragment-Based Approaches to Discover New Antibiotics |
| Q95325034 | Venturicidin A, A Membrane-active Natural Product Inhibitor of ATP synthase Potentiates Aminoglycoside Antibiotics |
| Q90663260 | Virulence-Inhibiting Herbal Compound Falcarindiol Significantly Reduced Mortality in Mice Infected with Pseudomonas aeruginosa |
| Q57112743 | Visual and Microscopic Evaluation of Streptomyces Developmental Mutants |
| Q52349670 | Whole-organism phenotypic screening for anti-infectives promoting host health. |
| Q90381334 | Zirconium Carboxyaminophosphonate Nanosheets as Support for Ag Nanoparticles |
| Q93167747 | Ziziphus mucronata Willd. (Rhamnaceae): it's botany, toxicity, phytochemistry and pharmacological activities |
Search more.