Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene

scientific article

Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1085101078
P356DOI10.1038/NBT.3843
P932PMC publication ID5462845
P698PubMed publication ID28459452

P50authorSatdarshan P MongaQ88533584
George MichalopoulosQ91297575
P2093author name stringJian-Hua Luo
Joel B Nelson
Yan P Yu
George Tseng
Ze-Hua Zuo
Silvia Liu
Zhang-Hui Chen
P2860cites workThe Hallmarks of CancerQ221226
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joiningQ34468164
Interaction of integrin-linked kinase and miniature chromosome maintenance 7-mediating integrin {alpha}7 induced cell growth suppressionQ34990955
CSR1 suppresses tumor growth and metastasis of prostate cancerQ35087938
Novel fusion transcripts associate with progressive prostate cancerQ35265643
Genomic Copy Number Variations in the Genomes of Leukocytes Predict Prostate Cancer Clinical Outcomes.Q35752335
p53-induced gene 3 mediates cell death induced by glutathione peroxidase 3.Q35956670
Characterization of Chromosome Changes in Two Human Prostatic Carcinoma Cell Lines (PC-3 and DU145) Using Chromosome Painting and Comparative Genomic HybridizationQ38504253
MAN2A1-FER Fusion Gene Is Expressed by Human Liver and Other Tumor Types and Has Oncogenic Activity in Mice.Q38714496
MCM7 amplification and overexpression are associated with prostate cancer progressionQ40358328
Gene therapy: adenovirus vectors.Q40835892
A simple method for the rapid generation of recombinant adenovirus vectorsQ40871252
Chromosomal analysis of human prostatic adenocarcinoma cell lines.Q42802487
Whole-genome methylation sequencing reveals distinct impact of differential methylations on gene transcription in prostate cancerQ47141373
Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma.Q55468006
Glutathione peroxidase 3, deleted or methylated in prostate cancer, suppresses prostate cancer growth and metastasisQ81098019
Concerning RNA-guided gene drives for the alteration of wild populationsQ21128771
Hallmarks of Cancer: The Next GenerationQ22252312
Multiplex genome engineering using CRISPR/Cas systemsQ24609428
Myopodin, a synaptopodin homologue, is frequently deleted in invasive prostate cancersQ24633414
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial ImmunityQ24669850
Expression of myopodin induces suppression of tumor growth and metastasisQ24672315
Discovery and Classification of Fusion Transcripts in Prostate Cancer and Normal Prostate TissueQ26997884
Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinasesQ28139775
Down-regulation of telomerase activity in malignant lymphomas by radiation and chemotherapeutic agentsQ28345325
A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2Q28366181
Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elementsQ29615788
Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificityQ29615792
DNA targeting specificity of RNA-guided Cas9 nucleasesQ29615793
CSR1 induces cell death through inactivation of CPSF3.Q33370902
(-)-Epigallocatechin-3-gallate induces Du145 prostate cancer cell death via downregulation of inhibitor of DNA binding 2, a dominant negative helix-loop-helix proteinQ33692811
Inhibition of prostate cancer growth and metastasis using small interference RNA specific for minichromosome complex maintenance component 7.Q33697912
Metallothionein 1 h tumour suppressor activity in prostate cancer is mediated by euchromatin methyltransferase 1Q33841451
Integrin alpha 7 interacts with high temperature requirement A2 (HtrA2) to induce prostate cancer cell deathQ34086887
Small molecules enhance CRISPR genome editing in pluripotent stem cells.Q34461590
P433issue6
P921main subjectsuicideQ10737
Cas9Q16965677
P304page(s)543-550
P577publication date2017-05-01
P1433published inNature BiotechnologyQ1893837
P1476titleTargeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene
P478volume35