| scholarly article | Q13442814 |
| P50 | author | Judith Campisi | Q19956736 |
| Wilfred F J van IJcken | Q47502980 | ||
| Peter de Keizer | Q63389959 | ||
| P2093 | author name string | Tobias Madl | |
| Jan H J Hoeijmakers | |||
| Jeroen Essers | |||
| Adriaan B Houtsmuller | |||
| Wiggert A van Cappellen | |||
| Ron W F de Bruin | |||
| Ingrid van der Pluijm | |||
| Joris Pothof | |||
| Julian D D Klein | |||
| Sarah Stryeck | |||
| Renata M C Brandt | |||
| Kasper W J Derks | |||
| Marjolein P Baar | |||
| Yvonne Rijksen | |||
| Benjamin R M Bourgeois | |||
| Danny A Feijtel | |||
| Diana A Putavet | |||
| Hester van Willigenburg | |||
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| Efficacy and safety of AM-111 in the treatment of acute sensorineural hearing loss: a double-blind, randomized, placebo-controlled phase II study. | Q34427102 | ||
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| p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype | Q35007977 | ||
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| Analysis of osteoarthritis in a mouse model of the progeroid human DNA repair syndrome trichothiodystrophy. | Q35201115 | ||
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| Markers of renal function tests | Q35966409 | ||
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| Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling | Q36590628 | ||
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| Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. | Q37345878 | ||
| Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network | Q37385995 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | apoptotic process | Q14599311 |
| tissue homeostasis | Q14873636 | ||
| P304 | page(s) | 132-147.e16 | |
| P577 | publication date | 2017-03-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging | |
| P478 | volume | 169 |
| Q93163071 | A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells |
| Q99566234 | A bidirectional crosstalk between autophagy and TP53 determines the pace of aging |
| Q90575658 | A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma |
| Q91723465 | A functional genetic screen defines the AKT-induced senescence signaling network |
| Q92107778 | A medicinal and edible formula YH0618 ameliorates the toxicity induced by Doxorubicin via regulating the expression of Bax/Bcl-2 and FOXO4 |
| Q92688982 | A proteomic atlas of senescence-associated secretomes for aging biomarker development |
| Q90101431 | A sirtuin's role in preventing senescence by protecting ribosomal DNA |
| Q57688652 | A versatile drug delivery system targeting senescent cells |
| Q90576187 | ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging |
| Q54982478 | Abnormalities in Skeletal Muscle Myogenesis, Growth, and Regeneration in Myotonic Dystrophy. |
| Q64085673 | Age-related dysfunction of the DNA damage response in intestinal stem cells |
| Q51829667 | Ageing: Targeting senescence-associated tissue damage. |
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| Q92233713 | Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset |
| Q47104199 | Apoptosis in the aging liver. |
| Q64119661 | Approaches towards Longevity: Reprogramming, Senolysis, and Improved Mitotic Competence as Anti-Aging Therapies |
| Q89985605 | Aspirin ameliorates the long-term adverse effects of doxorubicin through suppression of cellular senescence |
| Q93090089 | Autophagy Dysfunction, Cellular Senescence, and Abnormal Immune-Inflammatory Responses in AMD: From Mechanisms to Therapeutic Potential |
| Q89578028 | Beyond Tumor Suppression: Senescence in Cancer Stemness and Tumor Dormancy |
| Q58712798 | Biomarkers of Cellular Senescence and Skin Aging |
| Q52804662 | Blocking negative effects of senescence in human skin fibroblasts with a plant extract. |
| Q90249628 | Bone Marrow Senescence and the Microenvironment of Hematological Malignancies |
| Q89447778 | Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing |
| Q90475758 | CHRONIC KIDNEY DISEASE: A VICARIOUS RELATION TO PREMATURE CELL SENESCENCE? |
| Q48263663 | CIN and Aneuploidy: Different Concepts, Different Consequences. |
| Q57165494 | Cardiac ageing: extrinsic and intrinsic factors in cellular renewal and senescence |
| Q99551829 | Cell Senescence: A Nonnegligible Cell State under Survival Stress in Pathology of Intervertebral Disc Degeneration |
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| Q93082045 | Cellular Senescence and Iron Dyshomeostasis in Alzheimer's Disease |
| Q96303231 | Cellular Senescence and Senotherapies in the Kidney: Current Evidence and Future Directions |
| Q92237966 | Cellular Senescence and the Kidney: Potential Therapeutic Targets and Tools |
| Q90417537 | Cellular Senescence as a Therapeutic Target for Age-Related Diseases: A Review |
| Q89997239 | Cellular Senescence in the Kidney |
| Q39246705 | Cellular Senescence: A Translational Perspective |
| Q94476206 | Cellular plasticity and metastasis in breast cancer: a pre- and post-malignant problem |
| Q93075400 | Cellular senescence and radiation-induced pulmonary fibrosis |
| Q100558674 | Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche |
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| Q49851084 | Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives |
| Q49565626 | Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics |
| Q64056763 | Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis |
| Q48089331 | Cellular senescence in the aging and diseased kidney |
| Q91743238 | Cellular senescence in the lung across the age spectrum |
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| Q90140626 | Current perspective on the regulation of FOXO4 and its role in disease progression |
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| Q55077179 | Dopaminergic mediation in the brain aging and neurodegenerative diseases: a role of senescent cells. |
| Q58585294 | Editorial: Cancer Models |
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| Q55030277 | Effects of senolytic drugs on human mesenchymal stromal cells. |
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| Q93270345 | Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice |
| Q91659143 | Elimination of senescent osteoclast progenitors has no effect on the age-associated loss of bone mass in mice |
| Q89001536 | Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth |
| Q49384083 | Emerging roles of extracellular vesicles in cellular senescence and aging |
| Q92932432 | Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype |
| Q49523811 | Epigenetic Basis of Cellular Senescence and Its Implications in Aging |
| Q52324791 | Epigenetic Mechanisms Impacting Aging: A Focus on Histone Levels and Telomeres. |
| Q50193501 | Epigenetic regulation in cell senescence |
| Q64262011 | Epithelial innate immunity mediates tubular cell senescence after kidney injury |
| Q64118671 | Extension of Maximal Lifespan and High Bone Marrow Chimerism After Nonmyeloablative Syngeneic Transplantation of Bone Marrow From Young to Old Mice |
| Q94522036 | FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome |
| Q92782251 | FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice |
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| Q50137602 | FoxO transcription factors in cancer metabolism |
| Q57187699 | Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence |
| Q38659874 | Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology |
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| Q90350293 | Galactose-modified duocarmycin prodrugs as senolytics |
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| Q92967400 | Hallmarks of Aging in the Liver |
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| Q54979927 | Hydrogen sulfide ameliorates aging-associated changes in the kidney. |
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| Q52331716 | Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy. |
| Q39309490 | Inflammation and premature aging in advanced chronic kidney disease |
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| Q93160103 | Intracellular Peptides in Cell Biology and Pharmacology |
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| Q41183678 | Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis |
| Q61799432 | Jumonji C Demethylases in Cellular Senescence |
| Q92185092 | KLF2 induces the senescence of pancreatic cancer cells by cooperating with FOXO4 to upregulate p21 |
| Q92666602 | Knockdown of angiopoietin-like 2 induces clearance of vascular endothelial senescent cells by apoptosis, promotes endothelial repair and slows atherogenesis in mice |
| Q92618251 | Lactose induced redox-dependent senescence and activated Nrf2 pathway |
| Q42356261 | Licence to kill senescent cells in idiopathic pulmonary fibrosis? |
| Q57285536 | Linking cellular stress responses to systemic homeostasis |
| Q39328053 | Lipid (per) oxidation in mitochondria: an emerging target in the ageing process? |
| Q90154670 | LncRNA GUARDIN suppresses cellular senescence through a LRP130-PGC1α-FOXO4-p21-dependent signaling axis |
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| Q46134297 | Loss of lamin B1 is a biomarker to quantify cellular senescence in photoaged skin |
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| Q50063772 | Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence. |
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| Q55312849 | Non-Cell Autonomous Effects of the Senescence-Associated Secretory Phenotype in Cancer Therapy. |
| Q64063496 | Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis |
| Q64886178 | Optimization strategies for ACI: A step-chronicle review. |
| Q88688853 | Oxidation resistance 1 is a novel senolytic target |
| Q47927484 | Pathways from senescence to melanoma: focus on MITF sumoylation. |
| Q89669919 | Pharmacotherapy to gene editing: potential therapeutic approaches for Hutchinson-Gilford progeria syndrome |
| Q90268612 | Plasma exosomes in OSA patients promote endothelial senescence: effect of long-term adherent continuous positive airway pressure |
| Q39404378 | Proteostasis in cardiac health and disease. |
| Q50531270 | Proximity of Cytomegalovirus-Specific CD8+ T Cells to Replicative Senescence in Human Immunodeficiency Virus-Infected Individuals. |
| Q64122672 | Recent Advances in Cell Penetrating Peptide-Based Anticancer Therapies |
| Q50115780 | Recent insights into the cellular and molecular determinants of aging. |
| Q51773684 | Reflections on telomere dynamics and ageing-related diseases in humans. |
| Q52717506 | Regulation of cellular senescence via the FOXO4-p53 axis. |
| Q92678605 | Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age |
| Q64076963 | Relationships Between Ion Channels, Mitochondrial Functions and Inflammation in Human Aging |
| Q49383418 | Relevance of the p53-MDM2 axis to aging |
| Q64262055 | Replicative senescent human cells possess altered circadian clocks with a prolonged period and delayed peak-time |
| Q92425993 | Restored immune cell functions upon clearance of senescence in the irradiated splenic environment |
| Q90603663 | Retinoic acid inducible gene-I slows down cellular senescence through negatively regulating the integrin β3/p38 MAPK pathway |
| Q60932159 | Role of Forkhead Box O Transcription Factors in Oxidative Stress-Induced Chondrocyte Dysfunction: Possible Therapeutic Target for Osteoarthritis? |
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| Q55516438 | Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis. |
| Q90281563 | SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells |
| Q63916359 | Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2 |
| Q102054051 | Send in the senolytics |
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| Q64250359 | Senescent Cells in Early Vascular Ageing and Bone Disease of Chronic Kidney Disease-A Novel Target for Treatment |
| Q59677148 | Senescent Microvesicles: A Novel Advance in Molecular Mechanisms of Atherosclerotic Calcification |
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| Q93204940 | Senescent cells: A new Achilles' heel to exploit for cancer medicine? |
| Q88243444 | Senescent cells: a therapeutic target for cardiovascular disease |
| Q39449103 | Senescent cells: an emerging target for diseases of ageing |
| Q96577243 | Senolytic CAR T cells reverse senescence-associated pathologies |
| Q89169330 | Senolytic activity of piperlongumine analogues: Synthesis and biological evaluation |
| Q91987095 | Senolytics and Senostatics: A Two-Pronged Approach to Target Cellular Senescence for Delaying Aging and Age-Related Diseases |
| Q64286784 | Senolytics and senostatics as adjuvant tumour therapy |
| Q64272017 | Senotherapeutics: emerging strategy for healthy aging and age-related disease |
| Q99574277 | Single-cell analyses of aging, inflammation and senescence |
| Q54964433 | Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype. |
| Q52613750 | Strategies targeting cellular senescence. |
| Q88885453 | Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death |
| Q55618747 | T cell senescence and CAR-T cell exhaustion in hematological malignancies. |
| Q92654927 | Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging |
| Q107476758 | Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity |
| Q58721330 | Targeting senescence to delay progression of multiple sclerosis |
| Q91598124 | Targeting senescent cells: approaches, opportunities, challenges |
| Q89723568 | Targeting the progression of chronic kidney disease |
| Q92099306 | Telomere attrition predicts reduced survival in a wild social bird, but short telomeres do not |
| Q39312260 | The Clinical Potential of Senolytic Drugs |
| Q47132545 | The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy. |
| Q92636632 | The Evolving Role of CD8+CD28- Immunosenescent T Cells in Cancer Immunology |
| Q91811038 | The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut Feeling |
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| Q64898617 | The cell-penetrating FOXM1 N-terminus (M1-138) demonstrates potent inhibitory effects on cancer cells by targeting FOXM1 and FOXM1-interacting factor SMAD3. |
| Q61807694 | The curcumin analog EF24 is a novel senolytic agent |
| Q92232209 | The effect of retro-inverse D-amino acid Aβ-peptides on Aβ-fibril formation |
| Q39432413 | The emerging role of alternative splicing in senescence and aging. |
| Q92511767 | The emerging role of cellular senescence in renal diseases |
| Q48499773 | The quest for osteoporosis mechanisms and rational therapies: How far we've come, how much further we need to go. |
| Q95936711 | The quest to slow ageing through drug discovery |
| Q90246578 | The role of cellular senescence in ageing and endocrine disease |
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| Q50541793 | The role of telomeres in the mechanisms and evolution of life-history trade-offs and ageing. |
| Q90089213 | The senotherapeutic drug ABT-737 disrupts aberrant p21 expression to restore liver regeneration in adult mice |
| Q101564352 | Therapeutic strategies targeting FOXO transcription factors |
| Q50088224 | To stay young, kill zombie cells |
| Q92873304 | Transplanting cells from old but not young donors causes physical dysfunction in older recipients |
| Q90854384 | Turning back time with emerging rejuvenation strategies |
| Q93000927 | Unmasking senescence: context-dependent effects of SASP in cancer |
| Q60047178 | Urothelial Senescence in the Pathophysiology of Diabetic Bladder Dysfunction-A Novel Hypothesis |
| Q93216288 | Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity |
| Q51761509 | Vascular Senescence in Cardiovascular and Metabolic Diseases. |
| Q98771644 | Wnt Signaling Inhibits High-Density Cell Sheet Culture Induced Mesenchymal Stromal Cell Aging by Targeting Cell Cycle Inhibitor p27 |
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| Q59806849 | p53-Sensitive Epileptic Behavior and Inflammation in Hypomorphic Mice |
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