scholarly article | Q13442814 |
P50 | author | Chrisostomos Prodromou | Q28317140 |
P2093 | author name string | Laurence H Pearl | |
Zhaobo Li | |||
Velibor Savic | |||
Lihong Zhou | |||
P2860 | cites work | Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition | Q24297748 |
The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara | Q24306505 | ||
CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex | Q24336508 | ||
p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function | Q24554532 | ||
The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains | Q24599484 | ||
Building and remodelling Cullin-RING E3 ubiquitin ligases | Q27027816 | ||
Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues | Q27644429 | ||
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone | Q27740876 | ||
Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin | Q27766755 | ||
ErbB2 degradation mediated by the co-chaperone protein CHIP | Q28208008 | ||
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis | Q28276567 | ||
Interaction between syntaxin 8 and HECTd3, a HECT domain ligase | Q28587299 | ||
Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases | Q28609156 | ||
HSP90 at the hub of protein homeostasis: emerging mechanistic insights | Q29616824 | ||
Physiological functions of the HECT family of ubiquitin ligases | Q29617293 | ||
Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex | Q29617515 | ||
Animal HECT ubiquitin ligases: evolution and functional implications | Q33533462 | ||
E3 ubiquitin ligase Cullin-5 modulates multiple molecular and cellular responses to heat shock protein 90 inhibition in human cancer cells | Q33606911 | ||
ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo | Q33889333 | ||
Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu | Q34190181 | ||
ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system | Q34333456 | ||
Biogenesis of lysosome-related organelles complex-1 subunit 1 (BLOS1) interacts with sorting nexin 2 and the endosomal sorting complex required for transport-I (ESCRT-I) component TSG101 to mediate the sorting of epidermal growth factor receptor int | Q34355752 | ||
p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2. | Q34377527 | ||
Inhibition of HSP90 by AT13387 delays the emergence of resistance to BRAF inhibitors and overcomes resistance to dual BRAF and MEK inhibition in melanoma models | Q34677194 | ||
Hsp90 molecular chaperone inhibitors: are we there yet? | Q35655105 | ||
Hsp90 and Cdc37 -- a chaperone cancer conspiracy. | Q36015525 | ||
Inhibitors of the HSP90 molecular chaperone: current status | Q36543819 | ||
The HECTD3 E3 ubiquitin ligase suppresses cisplatin-induced apoptosis via stabilizing MALT1. | Q36567564 | ||
The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth | Q36926960 | ||
The HECTD3 E3 ubiquitin ligase facilitates cancer cell survival by promoting K63-linked polyubiquitination of caspase-8 | Q37357126 | ||
Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase | Q37453413 | ||
Hallmarks of alternative splicing in cancer | Q38171229 | ||
CHIP: a co-chaperone for degradation by the proteasome | Q38285306 | ||
Molecular functions of NEDD4 E3 ubiquitin ligases in cancer | Q38538927 | ||
Overcoming acquired BRAF inhibitor resistance in melanoma via targeted inhibition of Hsp90 with ganetespib | Q39036720 | ||
Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin | Q41168181 | ||
Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association | Q41282697 | ||
Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor | Q41617016 | ||
A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells | Q43577973 | ||
Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies | Q46551678 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
ImageQuant | Q112270642 | ||
P433 | issue | 12 | |
P304 | page(s) | 2515-2528 | |
P577 | publication date | 2017-06-01 | |
P1433 | published in | Cell Reports | Q5058165 |
P1476 | title | HECTD3 Mediates an HSP90-Dependent Degradation Pathway for Protein Kinase Clients | |
P478 | volume | 19 |
Q88641892 | Decanalizing thinking on genetic canalization |
Q58763474 | Expression profiling of ubiquitin-related genes in LKB1 mutant lung adenocarcinoma |
Q54111191 | Herpes Simplex Virus 1 Inhibits TANK-Binding Kinase 1 through Formation of the Us11-Hsp90 Complex. |
Q92864486 | Hsp90B enhances MAST1-mediated cisplatin resistance by protecting MAST1 from proteosomal degradation |
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Q90482001 | The functions and properties of cullin-5, a potential therapeutic target for cancers |
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