Production and characterization of functional recombinant hybrid heteropolymers of camel hepcidin and human ferritin H and L chains

scientific article published on 15 December 2016

Production and characterization of functional recombinant hybrid heteropolymers of camel hepcidin and human ferritin H and L chains is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/PROTEIN/GZW066
P698PubMed publication ID27980120

P50authorFernando CarmonaQ58575049
Alessandra GianoncelliQ43277715
Paolo ArosioQ56446594
P2093author name stringMohamed Nejib Marzouki
Maura Poli
Michela Asperti
Mohamed Boumaiza
Paola Ruzzenenti
Michela Bertuzzi
P2860cites workLEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activityQ24290410
Hepcidin, a urinary antimicrobial peptide synthesized in the liverQ24290609
Hepcidin revisited, disulfide connectivity, dynamics, and structureQ24651444
Tissue sulfhydryl groupsQ26778486
Mechanisms of mammalian iron homeostasisQ27010510
Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammationQ28186993
Regulation of iron metabolism by hepcidinQ28252744
Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cellsQ28507904
Presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and down-regulated by hepcidinQ28513640
Self-assembling influenza nanoparticle vaccines elicit broadly neutralizing H1N1 antibodiesQ30430925
Hepcidin targets ferroportin for degradation in hepatocytesQ33707486
Designed nanocage displaying ligand-specific Peptide bunches for high affinity and biological activityQ34362717
Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overloadQ35578602
Expression and purification of a new recombinant camel hepcidin able to promote the degradation of the iron exporter ferroportin1.Q35689860
The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function studyQ35848479
Circulating Hepcidin-25 Is Reduced by Endogenous Estrogen in HumansQ35920651
Hepcidin: iron-hormone and anti-microbial peptideQ36276140
Immunochemical characterization of human liver and heart ferritins with monoclonal antibodies.Q36430612
Hepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coliQ36624644
Modulation of hepcidin to treat iron deregulation: potential clinical applicationsQ36847852
Ferritins: a family of molecules for iron storage, antioxidation and more.Q37301997
Iron regulatory proteins: from molecular mechanisms to drug developmentQ37705384
Ferritin: a versatile building block for bionanotechnology.Q38356225
Development of an immunoassay for all human isoferritins, and its application to serum ferritin evaluationQ42102789
Molecular characterization of a novel hepcidin (HepcD) from Camelus dromedarius. Synthetic peptide forms exhibit antibacterial activityQ42664129
Distinct stability of recombinant L and H subunits of human ferritin: calorimetric and ANS binding studiesQ47775539
Production of biologically active forms of recombinant hepcidin, the iron-regulatory hormone.Q54420959
Recombinant ferritin: modulation of subunit stoichiometry in bacterial expression systems.Q54560494
P433issue2
P921main subjectCamelusQ7375
P304page(s)77-84
P577publication date2016-12-15
P1433published inProtein Engineering Design and SelectionQ15762396
P1476titleProduction and characterization of functional recombinant hybrid heteropolymers of camel hepcidin and human ferritin H and L chains
P478volume30