Transcriptional Repression of IFN Regulatory Factor 7 by MYC Is Critical for Type I IFN Production in Human Plasmacytoid Dendritic Cells

scientific article published on 14 September 2016

Transcriptional Repression of IFN Regulatory Factor 7 by MYC Is Critical for Type I IFN Production in Human Plasmacytoid Dendritic Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.1502385
P932PMC publication ID5101139
P698PubMed publication ID27630164

P50authorYin C LinQ55458944
Elise MuratQ95953253
P2093author name stringYong-Jun Liu
Virginia Pascual
HyeMee Joo
Seunghee Hong
Tae Whan Kim
Taeil Kim
P2860cites workA Toll-like receptor recognizes bacterial DNAQ24290668
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Myc represses transcription through recruitment of DNA methyltransferase corepressorQ24557458
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Immunomodulatory functions of type I interferonsQ26823904
c-Myc-regulated microRNAs modulate E2F1 expressionQ27861046
Regulation of the promoter activity of interferon regulatory factor-7 gene. Activation by interferon snd silencing by hypermethylationQ28115670
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c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation functionQ28143677
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Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivoQ28609049
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3Q28609763
Interferon regulatory factor-7 synergizes with other transcription factors through multiple interactions with p300/CBP coactivatorsQ28703540
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The nature of the principal type 1 interferon-producing cells in human bloodQ29619763
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Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cellsQ34209662
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MHC class II signaling function is regulated during maturation of plasmacytoid dendritic cellsQ44224972
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.Q52582850
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Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferonQ57275922
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A new mode of transcriptional repression by c-myc: methylationQ81232076
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IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblastsQ35122228
Regulation of IRF7 through cell type-specific protein stabilityQ35148066
Type I interferon modulation of cellular responses to cytokines and infectious pathogens: potential role in SLE pathogenesisQ35675517
Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expressionQ35774136
Dcp2 decapping protein modulates mRNA stability of the critical interferon regulatory factor (IRF) IRF-7.Q35806638
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Activation of type I interferon-dependent genes characterizes the "core response" induced by CpG DNA.Q36232223
The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infectionQ36402648
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responsesQ36567669
Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivoQ36589100
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Sin3 corepressor function in Myc-induced transcription and transformationQ37409356
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Activation of the transcription factor ISGF3 by interferon-gammaQ38322204
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OASL1 inhibits translation of the type I interferon-regulating transcription factor IRF7.Q39193091
The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptorQ39791268
C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphomaQ40185161
Virus or TLR agonists induce TRAIL-mediated cytotoxic activity of plasmacytoid dendritic cells.Q40338330
Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.Q40424280
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon inductionQ40437839
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} inductionQ40446857
Tamoxifen and interferon-beta for the treatment of metastatic breast cancer.Q40674553
Ras enhances Myc protein stability.Q40967066
Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cellsQ41477085
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The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone.Q41953880
Possible induction of systemic lupus erythematosus by interferon-α treatment in a patient with a malignant carcinoid tumourQ42099573
E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS eliminationQ42814364
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)3348-3359
P577publication date2016-09-14
P1433published inJournal of ImmunologyQ3521441
P1476titleTranscriptional Repression of IFN Regulatory Factor 7 by MYC Is Critical for Type I IFN Production in Human Plasmacytoid Dendritic Cells
P478volume197

Reverse relations

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Q40068214The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus

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