Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force

scientific article published on 29 May 2016

Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force is …
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scholarly articleQ13442814

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P356DOI10.1113/JP271893
P932PMC publication ID4967729
P698PubMed publication ID27477609

P2093author name stringQi Cao
Xian-Ping Dong
Xue Sun
Xi Zoë Zhong
P2860cites workIdentification of a vesicular nucleotide transporterQ34765722
Extracellular ATP as a signaling molecule for epithelial cellsQ35209159
Microglial migration mediated by ATP-induced ATP release from lysosomesQ36009219
Vesicular neurotransmitter transporters as targets for endogenous and exogenous toxic substancesQ36947112
P2X4: an ATP-activated ionotropic receptor cloned from rat brainQ37666937
From glutamate co-release to vesicular synergy: vesicular glutamate transportersQ37854416
Vesicular neurotransmitter transporter: bioenergetics and regulation of glutamate transportQ37879648
Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?Q38134724
Divalent cation transport by vesicular nucleotide transporterQ39708253
Involvement of SLC17A9-dependent vesicular exocytosis in the mechanism of ATP release during T cell activationQ40813156
Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosisQ41919650
Exome sequencing identifies SLC17A9 pathogenic gene in two Chinese pedigrees with disseminated superficial actinic porokeratosisQ42680081
SLC17A9 protein functions as a lysosomal ATP transporter and regulates cell viabilityQ42790544
ATP storage and uptake by isolated pancreatic zymogen granulesQ43074659
Mechanism underlying ATP release in human epidermal keratinocytesQ44250330
Regulated ATP release from astrocytes through lysosome exocytosisQ48112140
Mutation of histidine 286 of the human P2X4 purinoceptor removes extracellular pH sensitivityQ48896388
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neuronsQ57203231
Effects of ATP, vanadate, and molybdate on cathepsin D-catalyzed proteolysisQ69896619
Characterization of ATP transport into chromaffin granule ghosts. Synergy of ATP and serotonin accumulation in chromaffin granule ghostsQ71143969
The contents of adenine nucleotides, phosphagens and some glycolytic intermediates in resting muscles from vertebrates and invertebratesQ24530120
Multiplex genome engineering using CRISPR/Cas systemsQ24609428
Mechanism of ivermectin facilitation of human P2X4 receptor channelsQ24644507
Exploring the ATP-binding site of P2X receptorsQ26852221
Cathepsin D--many functions of one aspartic proteaseQ28275626
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomesQ28276964
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channelQ28294133
PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosomeQ29543488
Fusion-activated Ca2+ entry via vesicular P2X4 receptors promotes fusion pore opening and exocytotic content release in pneumocytesQ30503984
The solute carrier (SLC) complement of the human genome: phylogenetic classification reveals four major families.Q30849868
P2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH.Q33792971
The ABCs of membrane transporters in health and disease (SLC series): introductionQ34333686
The small chemical vacuolin-1 alters the morphology of lysosomes without inhibiting Ca2+-regulated exocytosisQ34360542
Physiological levels of ATP negatively regulate proteasome function.Q34376187
Cathepsin D deficiency is associated with a human neurodegenerative disorderQ34658270
P433issue15
P407language of work or nameEnglishQ1860
P1104number of pages14
P304page(s)4253-4266
P577publication date2016-05-29
P1433published inJournal of PhysiologyQ7743612
P1476titleActivation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force
P478volume594