Profiling gene mutations, translocations, and multidrug resistance in pediatric acute lymphoblastic leukemia: a step forward to personalizing medicine

scientific article published on 23 July 2016

Profiling gene mutations, translocations, and multidrug resistance in pediatric acute lymphoblastic leukemia: a step forward to personalizing medicine is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1006506656
P356DOI10.1007/S12032-016-0809-X
P698PubMed publication ID27449773

P2093author name stringSuraj K George
P Kusumakumary
R Shiji
T T Sreelekha
Manjusha Nair
Alphy Rose-James
P2860cites workIsolation and expression of a complementary DNA that confers multidrug resistanceQ24295219
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A case of pediatric B-Lymphoblastic leukemia presenting with a t(9;12)(p24;q11.2) involving JAK2 and concomitant MLL rearrangement with apparent insertion at 6q27Q34256192
The t(1;19)(q23;p13) results in consistent fusion of E2A and PBX1 coding sequences in acute lymphoblastic leukemiasQ34529043
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TEL/AML-1 fusion gene. its frequency and prognostic significance in childhood acute lymphoblastic leukemiaQ40735765
The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentialsQ41694396
FLT3 INHIBITORS: RECENT ADVANCES AND PROBLEMS FOR CLINICAL APPLICATION.Q43188286
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Expression of multidrug resistance 1 (MDR1), multidrug resistance-related protein 1 (MRP1), lung resistance protein (LRP), and breast cancer resistance protein (BCRP) genes and clinical outcome in childhood acute lymphoblastic leukemia.Q53527272
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Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications.Q54242225
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Acute lymphoblastic leukaemiaQ56722375
E2A-PBX1 fusion in adult acute lymphoblastic leukaemia: biological and clinical featuresQ60171404
Tandem duplication of the FLT3 gene in acute lymphoblastic leukemia: a marker for the monitoring of minimal residual diseaseQ73555805
Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemiaQ73631267
Cytogenetics and prognosis in childhood lymphoblastic leukaemia: results of MRC UKALL X. Medical Research Council Working Party in Childhood LeukaemiaQ73851055
Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemiaQ74576864
Acute lymphoblastic leukemiaQ77153499
Association of 5' CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cellsQ78016517
Translocation t(1;19) is related to low cellular drug resistance in childhood acute lymphoblastic leukaemiaQ80962315
P433issue9
P921main subjectmultiple drug resistanceQ643839
lymphoblastic leukemiaQ18553852
P304page(s)98
P577publication date2016-07-23
P1433published inMedical OncologyQ2152666
P1476titleProfiling gene mutations, translocations, and multidrug resistance in pediatric acute lymphoblastic leukemia: a step forward to personalizing medicine
P478volume33