Metformin; a review of its history and future: from lilac to longevity

scientific article published on February 2017

Metformin; a review of its history and future: from lilac to longevity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/PEDI.12473
P698PubMed publication ID28052534

P2093author name stringBrigid Gregg
Inas Thomas
P2860cites workMetformin: An UpdateQ22241145
Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 DiabetesQ22241283
Incidence of lactic acidosis in metformin usersQ22241284
Metformin Treatment to Prevent Early Puberty in Girls with Precocious PubarcheQ22241661
Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or MetforminQ22250892
Repurposing metformin: an old drug with new tricks in its binding pocketsQ22250976
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenaseQ22251079
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMPQ22251081
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes StudyQ24633604
Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC.Q39340562
Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in miceQ39640373
Synergistic Benefit of Statin and Metformin in Gastrointestinal MalignanciesQ40950693
Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain InjuryQ42041465
Effect of Metformin on mortality in patients with heart failure and type 2 diabetes mellitusQ42883064
Pubertal metformin therapy to reduce total, visceral, and hepatic adiposityQ43272937
Metformin treatment for four years to reduce total and visceral fat in low birth weight girls with precocious pubarche.Q46719157
Metformin treatment to reduce central adiposity after prenatal growth restraint: a placebo-controlled pilot study in prepubertal children.Q50458133
Effect of metformin treatment on insulin action in diabetic rats: in vivo and in vitro correlations.Q51616426
Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of DiabetesQ24642503
Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition at 2 years of age.Q30407478
Clinical review: Drugs commonly associated with weight change: a systematic review and meta-analysisQ33570239
A risk-benefit assessment of metformin in type 2 diabetes mellitusQ33678321
Potential biomarker of metformin actionQ33686430
Metformin pharmacogenomics: current status and future directionsQ33959731
An update on the pharmacogenomics of metformin: progress, problems and potentialQ34003050
Effects of low dose metformin in adolescents with type I diabetes mellitus: a randomized, double-blinded placebo-controlled studyQ34288242
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Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.Q34506457
Short- and long-term outcomes of metformin compared with insulin alone in pregnancy: a systematic review and meta-analysisQ34525288
Metformin--mode of action and clinical implications for diabetes and cancerQ34658712
Traditional plant medicines as treatments for diabetesQ34675107
Metabolic effects of metformin in non-insulin-dependent diabetes mellitusQ34720764
Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trialQ35031127
Metformin use and lung cancer risk in patients with diabetes.Q35046673
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiotaQ35860108
Therapeutic Challenges in Diabetes Prevention: We Have Not Found the "Exercise Pill"Q35880380
Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes StudyQ36217890
Lipid and inflammatory cardiovascular risk worsens over 3 years in youth with type 2 diabetes: the TODAY clinical trialQ36868110
Effects of Metformin and Exercise Training, Alone or in Combination, on Cardiac Function in Individuals with Insulin ResistanceQ36999950
Once-daily delayed-release metformin lowers plasma glucose and enhances fasting and postprandial GLP-1 and PYY: results from two randomised trialsQ37059366
Treatment with L-citrulline and metformin in Duchenne muscular dystrophy: study protocol for a single-centre, randomised, placebo-controlled trialQ37150891
Metformin: prevention and treatment of antipsychotic-induced weight gainQ37378262
An energetic tale of AMPK-independent effects of metformin.Q37767575
Efficacy and safety of metformin for treatment of overweight and obesity in adolescents: an updated systematic review and meta-analysis.Q38056388
Metformin: from mechanisms of action to therapiesQ38279824
Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes: A Randomized Clinical TrialQ38399028
Evaluating the Effects of Metformin Use on Height in Children and Adolescents: A Meta-analysis of Randomized Clinical TrialsQ38594496
Insulin resistance, role of metformin and other non-insulin therapies in pediatric type 1 diabetesQ38642435
Reasons and outcomes of conversion of laparoscopic sleeve gastrectomy to Roux-en-Y gastric bypass for nonrespondersQ38708649
Adjunctive metformin for antipsychotic-induced hyperprolactinemia: A systematic reviewQ38715241
Involvement of glucagon-like peptide-1 in the glucose-lowering effect of metformin.Q38855893
Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trialQ38996447
P433issue1
P921main subjectmetforminQ19484
P304page(s)10-16
P577publication date2017-02-01
P1433published inPediatric DiabetesQ7159203
P1476titleMetformin; a review of its history and future: from lilac to longevity
P478volume18

Reverse relations

cites work (P2860)
Q48302673A Review of Insulin Resistance in Type 1 Diabetes: Is There a Place for Adjunctive Metformin?
Q47240106A reappraisal on metformin
Q64254281Association of preadmission metformin use and mortality in patients with sepsis and diabetes mellitus: a systematic review and meta-analysis of cohort studies
Q60698427Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers
Q49193708Comparative Study on Adding Pioglitazone or Sitagliptin to Patients with Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin
Q93364919Diabetes pharmacotherapy and effects on the musculoskeletal system
Q64114703Distinct Fractions of an Extract Contain Compounds With Novel Adipogenic Bioactivity
Q93079853Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels
Q51733866Groundsel Bush (Baccharis halimifolia) Extract Promotes Adipocyte Differentiation In Vitro and Increases Adiponectin Expression in Mature Adipocytes.
Q62495171Machine Learning on Human Muscle Transcriptomic Data for Biomarker Discovery and Tissue-Specific Drug Target Identification
Q52668163Metformin and berberine, two versatile drugs in treatment of common metabolic diseases.
Q50050510Metformin for Rapidly Maturing Girls with Central Adiposity: Less Liver Fat and Slower Bone Maturation
Q39376655Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity
Q38692444Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies.
Q50015016Population specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern European patient populations.
Q44871485Structural constraints and importance of caffeic acid moiety for anti-hyperglycemic effects of caffeoylquinic acids from chicory
Q94528642Translational Geroscience: From invertebrate models to companion animal and human interventions

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