EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice

scientific article published on 18 April 2016

EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1004792109
P356DOI10.1038/SREP24580
P932PMC publication ID5263857
P698PubMed publication ID27087279
P5875ResearchGate publication ID301508492

P2093author name stringYi Wang
Jun Wang
Yali Zhang
Xiaokun Li
Weixin Li
Guang Liang
Jingying Wang
Lingfeng Chen
Lintao Wang
Peng Zhong
Qilu Fang
P2860cites workERBB1/EGFR and ERBB2 (HER2/neu)--targeted therapies in cancer and cardiovascular system with cardiovascular drugs.Q54329358
Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart StudyQ72779135
A role of heparin-binding epidermal growth factor-like growth factor in cardiac remodeling after myocardial infarctionQ74800826
Angiotensin II-induced transactivation of epidermal growth factor receptor regulates fibronectin and transforming growth factor-beta synthesis via transcriptional and posttranscriptional mechanismsQ77744387
An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophyQ80093639
Potential use of an anticancer drug gefinitib, an EGFR inhibitor, on allergic airway inflammationQ80550710
The epidermal growth factor receptors and their family of ligands: their putative role in atherogenesisQ24312466
Molecular mechanisms of cancer development in obesityQ28253823
Impact of obesity on cardiac metabolism, fibrosis, and function.Q30369122
Transactivation of the epidermal growth factor receptor by heat shock protein 90 via Toll-like receptor 4 contributes to the migration of glioblastoma cellsQ30498022
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in miceQ34178121
Can We Prevent Obesity-Related Metabolic Diseases by Dietary Modulation of the Gut Microbiota?Q35895693
Erlotinib protects against LPS-induced endotoxicity because TLR4 needs EGFR to signalQ35946356
Tackling the EGFR in pathological tissue remodellingQ36175280
Punicalagin, an active component in pomegranate, ameliorates cardiac mitochondrial impairment in obese rats via AMPK activationQ36274048
Increased epidermal growth factor-like ligands are associated with elevated vascular nicotinamide adenine dinucleotide phosphate oxidase in a primate model of atherosclerosisQ36319377
Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ miceQ37264435
Macrophages and fibroblasts during inflammation, tissue damage and organ injuryQ37410537
A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitusQ37560339
Targeting non-malignant disorders with tyrosine kinase inhibitors.Q37814085
NF-κB, inflammation, and metabolic disease.Q37825008
Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II.Q38555026
EGFR inhibition protects cardiac damage and remodeling through attenuating oxidative stress in STZ-induced diabetic mouse modelQ38901466
Toll-like receptor 4 differentially regulates epidermal growth factor-related growth factors in response to intestinal mucosal injuryQ39700792
Helicobacter pylori protein HP0175 transactivates epidermal growth factor receptor through TLR4 in gastric epithelial cellsQ39937536
Activation of the epidermal growth factor receptor (EGFR) by a novel metalloprotease pathway.Q39943187
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.Q40816506
Activation of epithelial growth factor receptor pathway by unsaturated fatty acidsQ40918772
Regulation of epidermal-growth-factor-receptor signal transduction by cis-unsaturated fatty acids. Evidence for a protein kinase C-independent mechanismQ41665311
Obesity-related cardiomyopathy is an adipocyte-mediated paracrine diseaseQ42333851
Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunityQ42810693
Antisense to epidermal growth factor receptor prevents the development of left ventricular hypertrophyQ44353860
The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinaseQ48084939
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecthyperlipidemiaQ1079120
P304page(s)24580
P577publication date2016-04-18
P1433published inScientific ReportsQ2261792
P1476titleEGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice
P478volume6

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cites work (P2860)
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