Rational design of multifunctional small-molecule prodrugs for simultaneous suppression of cancer cell growth and metastasis in vitro and in vivo

scientific article published on 30 March 2016

Rational design of multifunctional small-molecule prodrugs for simultaneous suppression of cancer cell growth and metastasis in vitro and in vivo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C5CC10367C
P698PubMed publication ID27027105

P2093author name stringLingling Li
Haiyang Xie
Lin Zhou
Shusen Zheng
Xiao Xu
Jianguo Wang
Hangxiang Wang
Tao Fang
Jianmei Chen
P2860cites workBiotin-guided anticancer drug delivery with acidity-triggered drug releaseQ38877017
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EphA2 Up-regulation induced by deoxycholic acid in human colon carcinoma cells, an involvement of extracellular signal-regulated kinase and p53-independenceQ40625283
Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular CarcinomaQ41074002
Identification and activities of human carboxylesterases for the activation of CPT-11, a clinically approved anticancer drugQ43804754
An activatable theranostic for targeted cancer therapy and imaging.Q51747526
Timeline: Chemotherapy and the war on cancer.Q53313789
A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing TumorsQ57911941
A bivalent small molecule-drug conjugate directed against carbonic anhydrase IX can elicit complete tumour regression in miceQ57911942
Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodellingQ57983629
Bis-sulfide bioconjugates for glutathione triggered tumor responsive drug releaseQ58202911
A perspective on cancer cell metastasisQ28307891
Tumour-cell invasion and migration: diversity and escape mechanismsQ29547894
Antibody conjugate therapeutics: challenges and potentialQ34224801
Small targeted cytotoxics: current state and promises from DNA-encoded chemical librariesQ34538606
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Tissue-penetrating delivery of compounds and nanoparticles into tumorsQ35016106
Structure-based rational design of prodrugs to enable their combination with polymeric nanoparticle delivery platforms for enhanced antitumor efficacy.Q35241553
Non-invasive, real-time reporting drug release in vitro and in vivoQ35800904
Neuropilins in tumor biologyQ37400423
Unravelling the complexity of metastasis - molecular understanding and targeted therapiesQ37937424
Prodrug and nanomedicine approaches for the delivery of the camptothecin analogue SN38.Q38127545
Antibody-drug conjugates: an emerging concept in cancer therapyQ38200071
Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance.Q38311815
Cell-specific, activatable, and theranostic prodrug for dual-targeted cancer imaging and therapyQ38785651
P433issue32
P921main subjectcell growthQ189159
P304page(s)5601-5604
P577publication date2016-03-30
P1433published inChemical CommunicationsQ426303
P1476titleRational design of multifunctional small-molecule prodrugs for simultaneous suppression of cancer cell growth and metastasis in vitro and in vivo
P478volume52

Reverse relations

cites work (P2860)
Q57377325A facile supramolecular approach to fabricate multifunctional upconversion nanoparticles as a versatile platform for drug loading, in vivo delivery and tumor imaging
Q40333912Albumin nanoparticle encapsulation of potent cytotoxic therapeutics shows sustained drug release and alleviates cancer drug toxicity
Q43095122Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations.
Q47427416Self-assembly of peptide amphiphiles for drug delivery: the role of peptide primary and secondary structures.
Q64890853The regio-selective synthesis of 10-hydroxy camptothecin norcantharidin conjugates and their biological activity evaluation in vitro.

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