Hypoxia enhances tenocyte differentiation of adipose-derived mesenchymal stem cells by inducing hypoxia-inducible factor-1α in a co-culture system

scientific article published on 29 March 2016

Hypoxia enhances tenocyte differentiation of adipose-derived mesenchymal stem cells by inducing hypoxia-inducible factor-1α in a co-culture system is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/CPR.12250
P932PMC publication ID6496829
P698PubMed publication ID27021233

P2093author name stringYing Chen
Yang Yu
Tao Cheng
Yulong Zhou
Jianjun Hong
Kehe Yu
Yifei Zhou
Xiaolang Lu
P2860cites workDifferential effects of hypoxia on osteochondrogenic potential of human adipose-derived stem cells.Q43235373
Hypoxia induces osteogenesis in rabbit adipose-derived stem cells overexpressing bone morphogenic protein-2.Q43874393
Porous membrane with reverse gradients of PDGF-BB and BMP-2 for tendon-to-bone repair: in vitro evaluation on adipose-derived stem cell differentiationQ44790974
Trophic effects of mesenchymal stem cells increase chondrocyte proliferation and matrix formation.Q45196670
Equine adipose-tissue derived mesenchymal stem cells and platelet concentrates: their association in vitro and in vivoQ46443669
Co-culture of human adipose-derived stem cells with tenocytes increases proliferation and induces differentiation into a tenogenic lineageQ48408305
Co-culture with cardiomyocytes enhanced the myogenic conversion of mesenchymal stromal cells in a dose-dependent manner.Q50569820
Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cells.Q51726624
HIF1alpha regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis.Q51976057
Development of a new co-culture system, the "separable-close co-culture system," to enhance stem-cell-to-chondrocyte differentiation.Q53229346
Human adipose-derived stem cells accelerate the restoration of tensile strength of tendon and alleviate the progression of rotator cuff injury in a rat model.Q53625490
Defined xenogeneic-free and hypoxic environment provides superior conditions for long-term expansion of human adipose-derived stem cells.Q53656252
Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potentialsQ59135959
Hypoxia-preconditioned adipose tissue-derived mesenchymal stem cell increase the survival and gene expression of engineered neural stem cells in a spinal cord injury modelQ82886945
A review on the use of cell therapy in the treatment of tendon disease and injuriesQ28251262
Adipose-derived mesenchymal stem cells treated with growth differentiation factor-5 express tendon-specific markersQ30430940
Osteogenic differentiation of adipose-derived stem cells is hypoxia-inducible factor-1 independentQ30540100
Use of culture geometry to control hypoxia-induced vascular endothelial growth factor secretion from adipose-derived stem cells: optimizing a cell-based approach to drive vascular growthQ30554316
Indirect co-culture with tendons or tenocytes can program amniotic epithelial cells towards stepwise tenogenic differentiationQ34163318
Hypoxia-inducible factors, stem cells, and cancerQ34625782
Biologics for tendon repairQ35900746
Randomized placebo-controlled dose-ranging and pharmacodynamics study of roxadustat (FG-4592) to treat anemia in nondialysis-dependent chronic kidney disease (NDD-CKD) patientsQ36058555
Hypoxia enhances proliferation and stemness of human adipose-derived mesenchymal stem cellsQ36237006
Equine tendonitis therapy using mesenchymal stem cells and platelet concentrates: a randomized controlled trial.Q37372264
Indirect co-culture with tenocytes promotes proliferation and mRNA expression of tendon/ligament related genes in rat bone marrow mesenchymal stem cellsQ37480969
The role of prolyl hydroxylase domain protein (PHD) during rosiglitazone-induced adipocyte differentiation.Q37536518
Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix.Q37634215
Tendon regeneration and repair with adipose derived stem cellsQ37639353
Hypoxia and adipose-derived stem cell-based tissue regeneration and engineering.Q37854071
Concise review: human adipose-derived stem cells: separating promise from clinical needQ37855743
Cellular and molecular stimulation of adipose-derived stem cells under hypoxiaQ38180398
Mitochondrial complex III ROS regulate adipocyte differentiationQ38666697
In vitro mutual interaction between tenocytes and adipose-derived mesenchymal stromal cellsQ39080298
[(4-Hydroxyl-benzo[4,5]thieno[3,2-c]pyridine-3-carbonyl)-amino]-acetic acid derivatives; HIF prolyl 4-hydroxylase inhibitors as oral erythropoietin secretagoguesQ39095004
Differentiation of adipose-derived stem cells for tendon repair.Q39816444
Schwann-like cell differentiation of rat adipose-derived stem cells by indirect co-culture with Schwann cells in vitro.Q39821962
Comparative study on functional effects of allotransplantation of bone marrow stromal cells and adipose derived stromal vascular fraction on tendon repair: a biomechanical study in rabbitsQ40176254
Human adipose-derived stem cells display myogenic potential and perturbed function in hypoxic conditionsQ40324028
Reduction of reactive oxygen species ameliorates metabolism-secretion coupling in islets of diabetic GK rats by suppressing lactate overproductionQ40946041
Hypoxia, HIFs and bone developmentQ41812685
Differentiation arrest by hypoxiaQ42797711
P433issue2
P921main subjecttendon cellQ7699651
hypoxiaQ105688
mesenchymal stem cellQ1922379
roxadustatQ27088611
P304page(s)173-184
P577publication date2016-03-29
P1433published inCell ProliferationQ1952798
P1476titleHypoxia enhances tenocyte differentiation of adipose-derived mesenchymal stem cells by inducing hypoxia-inducible factor-1α in a co-culture system
P478volume49

Reverse relations

cites work (P2860)
Q90348411From the perspective of embryonic tendon development: various cells applied to tendon tissue engineering
Q99555728In Vitro Innovation of Tendon Tissue Engineering Strategies
Q37228761Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study
Q47726440Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation
Q55110887Physioxia: a more effective approach for culturing human adipose-derived stem cells for cell transplantation.
Q47258231Tendon explant cultures to study the communication between adipose stem cells and native tendon niche.

Search more.