A novel derivative of tetrandrine (H1) induces endoplasmic reticulum stress-mediated apoptosis and prosurvival autophagy in human non-small cell lung cancer cells

scientific article published on 4 February 2016

A novel derivative of tetrandrine (H1) induces endoplasmic reticulum stress-mediated apoptosis and prosurvival autophagy in human non-small cell lung cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1049977191
P356DOI10.1007/S13277-016-4950-0
P698PubMed publication ID26846103

P50authorLing SuQ59451808
P2093author name stringYu Wang
Yidan Lin
Xiangguo Liu
Xianfang Liu
Jiamei Yan
P2860cites workCHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cellsQ24301679
Roles of CHOP/GADD153 in endoplasmic reticulum stressQ24302185
EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistanceQ24335999
FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosisQ24548247
Atomistic autophagy: the structures of cellular self-digestionQ27028021
Death receptors: signaling and modulationQ28280897
Apoptosis: a review of programmed cell deathQ28305845
Methods in mammalian autophagy researchQ29547276
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunitiesQ29617768
New insights into apoptosis signaling by Apo2L/TRAIL.Q34022690
Roles of c-FLIP in Apoptosis, Necroptosis, and AutophagyQ34449938
Tetrandrine Suppresses Cancer Angiogenesis and Metastasis in 4T1 Tumor Bearing MiceQ34769302
TRAIL and its receptors as targets for cancer therapyQ35927476
The caspase-8 modulator c-FLIP.Q36099496
Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells.Q37043022
Salermide up-regulates death receptor 5 expression through the ATF4-ATF3-CHOP axis and leads to apoptosis in human cancer cellsQ37295559
Tetrandrine blocks autophagic flux and induces apoptosis via energetic impairment in cancer cellsQ37680285
The role of autophagy in cancer: therapeutic implicationsQ37924056
Tetrandrine induces cell death in SAS human oral cancer cells through caspase activation-dependent apoptosis and LC3-I and LC3-II activation-dependent autophagyQ39148997
PKCδ regulates death receptor 5 expression induced by PS-341 through ATF4-ATF3/CHOP axis in human lung cancer cells.Q39305270
H1, a derivative of Tetrandrine, exerts anti-MDR activity by initiating intrinsic apoptosis pathway and inhibiting the activation of Erk1/2 and Akt1/2.Q39485388
H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein.Q39678602
Involvement of c-FLIP and survivin down-regulation in flexible heteroarotinoid-induced apoptosis and enhancement of TRAIL-initiated apoptosis in lung cancer cellsQ39918813
The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells.Q40134426
Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous proteinQ40402303
Coupling of endoplasmic reticulum stress to CDDO-Me-induced up-regulation of death receptor 5 via a CHOP-dependent mechanism involving JNK activationQ41131934
Tetrandrine prevents acquired drug resistance of K562 cells through inhibition of mdr1 gene transcriptionQ43245983
CAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction is a major component of SHetA2-induced apoptosis in lung cancer cells.Q46507423
Combination of Tetrandrine with cisplatin enhances cytotoxicity through growth suppression and apoptosis in ovarian cancer in vitro and in vivo.Q53266848
Autophagy. Explaining exerciseQ83302132
P433issue8
P921main subjectendoplasmic reticulumQ79927
autophagyQ288322
P304page(s)10403-10413
P577publication date2016-02-04
P1433published inTumor BiologyQ15757842
P1476titleA novel derivative of tetrandrine (H1) induces endoplasmic reticulum stress-mediated apoptosis and prosurvival autophagy in human non-small cell lung cancer cells
P478volume37

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cites work (P2860)
Q64269060High Performance Liquid Chromatography Determination and Optimization of the Extraction Process for the Total Alkaloids from Traditional Herb Hayata
Q37690890Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer
Q91918858Targeting the unfolded protein response in head and neck and oral cavity cancers
Q37685102Tetrandrine Exerts a Radiosensitization Effect on Human Glioma through Inhibiting Proliferation by Attenuating ERK Phosphorylation
Q38740290Tetrandrine Induces Apoptosis of Human Nasopharyngeal Carcinoma NPC-TW 076 Cells through Reactive Oxygen Species Accompanied by an Endoplasmic Reticulum Stress Signaling Pathway.
Q26749391Tetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapy