scholarly article | Q13442814 |
P50 | author | Roy A Quinlan | Q56493450 |
P2093 | author name string | Stephen Barnes | |
P2860 | cites work | Radiocarbon dating of the human eye lens crystallines reveal proteins without carbon turnover throughout life | Q21092225 |
Molecular cloning of human mevalonate kinase and identification of a missense mutation in the genetic disease mevalonic aciduria | Q24292898 | ||
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans | Q24339604 | ||
LP2, a differentiation-associated lipid-binding protein expressed in bovine lens | Q24529986 | ||
Mutations in the Delta7-sterol reductase gene in patients with the Smith-Lemli-Opitz syndrome | Q24670249 | ||
Non-cardiovascular effects associated with statins | Q27026332 | ||
αA-crystallin peptide SDRDKFVIFLDVKHF accumulating in aging lens impairs the function of α-crystallin and induces lens protein aggregation | Q27345377 | ||
The structured core domain of B-crystallin can prevent amyloid fibrillation and associated toxicity | Q27683083 | ||
Membrane proteins bind lipids selectively to modulate their structure and function. | Q27684088 | ||
Lanosterol reverses protein aggregation in cataracts | Q28114922 | ||
Toxicologic lesions associated with two related inhibitors of oxidosqualene cyclase in the dog and mouse | Q28203261 | ||
Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat | Q28566325 | ||
No turnover in lens lipids for the entire human lifespan | Q28650424 | ||
Lipids and the ocular lens | Q28749880 | ||
Alpha-crystallin can function as a molecular chaperone | Q29618672 | ||
Comprehensive analysis of maillard protein modifications in human lenses: effect of age and cataract | Q30316666 | ||
NMR-detected brownian dynamics of αB-crystallin over a wide range of concentrations | Q30316863 | ||
Lens β-crystallins: the role of deamidation and related modifications in aging and cataract. | Q30360031 | ||
A method to prevent protein delocalization in imaging mass spectrometry of non-adherent tissues: application to small vertebrate lens imaging | Q30389464 | ||
Examining the influence of ultraviolet C irradiation on recombinant human γD-crystallin. | Q30398019 | ||
Tissue localization and solubilities of αA-crystallin and its numerous C-terminal truncation products in pre- and postcataractous ICR/f rat lenses | Q30476044 | ||
Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat. | Q30498113 | ||
Pharmacological chaperone for α-crystallin partially restores transparency in cataract models | Q30700509 | ||
Quantitative measurement of deamidation in lens betaB2-crystallin and peptides by direct electrospray injection and fragmentation in a Fourier transform mass spectrometer | Q33231198 | ||
Protein aging: truncation of aquaporin 0 in human lens regions is a continuous age-dependent process | Q33398876 | ||
Age-related changes in the spatial distribution of human lens alpha-crystallin products by MALDI imaging mass spectrometry | Q33433847 | ||
UVA light-excited kynurenines oxidize ascorbate and modify lens proteins through the formation of advanced glycation end products: implications for human lens aging and cataract formation | Q33761317 | ||
Nutritional modulation of cataract | Q33900780 | ||
Volume change of the ocular lens during accommodation. | Q50992209 | ||
NMR spectroscopy of human eye tissues: a new insight into ocular biochemistry. | Q53657385 | ||
Photooxidation of lens alpha-crystallin by hypericin (active ingredient in St. John's Wort). | Q55034161 | ||
Small-angle X-ray scattering studies of the intact eye lens: effect of crystallin composition and concentration on microstructure | Q56948957 | ||
Cholesterol Oxides Accumulate in Human Cataracts | Q57843441 | ||
In vitro studies on the photosensitized oxidation of lens proteins by porphyrins | Q68683568 | ||
Defective superoxide-dismutase molecules accumulate with age in human lenses | Q68957655 | ||
G6PD molecules devoid of catalytic activity are present in the nucleus of the rat lens | Q69545778 | ||
Age-dependent changes in the distribution and concentration of human lens cholesterol and phospholipids | Q69685350 | ||
Electrogenic Na+-ascorbate cotransport in cultured bovine pigmented ciliary epithelial cells | Q69938392 | ||
Dietary prevention of cataracts in the pink-eyed RCS rat | Q70076284 | ||
Lipids of human lens fiber cell membranes | Q70585122 | ||
Glyceraldehyde 3-phosphate dehydrogenase activity in rat and human lenses and the fate of enzyme molecules in the aging lens | Q70740627 | ||
Filensin is proteolytically processed during lens fiber cell differentiation by multiple independent pathways | Q71814604 | ||
Binding capacity of alpha-crystallin to bovine lens lipids | Q71836243 | ||
Genetic analysis of a Japanese cerebrotendinous xanthomatosis family: identification of a novel mutation in the adrenodoxin binding region of the CYP 27 gene | Q71847797 | ||
A protective role for glutathione-dependent reduction of dehydroascorbic acid in lens epithelium | Q71959544 | ||
Ascorbic acid mediated alteration of alpha-crystallin secondary structure | Q72281256 | ||
Selenite cataract and its attenuation by vitamin E in Wistar rats | Q73585108 | ||
Singlet oxygen production correlates with his and Trp destruction in brunescent cataract water-insoluble proteins | Q77431479 | ||
An impediment to glutathione diffusion in older normal human lenses: a possible precondition for nuclear cataract | Q77759968 | ||
Effect of the isoflavone genistein against galactose-induced cataracts in rats | Q79486102 | ||
Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibility | Q81529613 | ||
alpha-Crystallin binding in vitro to lipids from clear human lenses | Q81871040 | ||
Phospholipid composition of the rat lens is independent of diet | Q81973716 | ||
Alterations in the lenticular protein profile in experimental selenite-induced cataractogenesis and prevention by ellagic acid | Q83761221 | ||
Response to letter on "statins use and risk of cataracts: firm conclusions are still far off" | Q87121513 | ||
The small heat shock proteins family: the long forgotten chaperones | Q37997166 | ||
The evolution of lenses | Q38051403 | ||
Dynamical structure of αB-crystallin. | Q38199864 | ||
Preserve the (intraocular) environment: the importance of maintaining normal oxygen gradients in the eye. | Q38200972 | ||
The etiology of human age-related cataract. Proteins don't last forever | Q38575861 | ||
Tight binding of proteins to membranes from older human cells. | Q39239294 | ||
Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity | Q39984142 | ||
Calcium and the Physiology of Cataract | Q40079504 | ||
Anti-inflammatory effects of isoflavones are dependent on flow and human endothelial cell PPARgamma | Q40181191 | ||
C-terminal interactions mediate the quaternary dynamics of αB-crystallin. | Q40183520 | ||
Delivery of glutathione to the lens nucleus | Q41442727 | ||
Cataracts in the Smith-Lemli-Opitz syndrome | Q41938344 | ||
Partially folded aggregation intermediates of human gammaD-, gammaC-, and gammaS-crystallin are recognized and bound by human alphaB-crystallin chaperone | Q42073561 | ||
Glycation by ascorbic acid oxidation products leads to the aggregation of lens proteins | Q42174300 | ||
Mevalonic aciduria--an inborn error of cholesterol and nonsterol isoprene biosynthesis | Q42205835 | ||
Fluorescence studies on tryptophan and sulfhydryl group changes of bovine lens crystallins in a photodynamic system | Q42229141 | ||
Moringa oleiferaPrevents Selenite-Induced Cataractogenesis in Rat Pups | Q42873732 | ||
Age-dependent denaturation of enzymes in the human lens: a paradigm for organismic aging? | Q43002298 | ||
Low vitamin E level as a subliminal risk factor in a rat model of prednisolone-induced cataract | Q43940026 | ||
Procyanidin-rich extract from grape seeds prevents cataract formation in hereditary cataractous (ICR/f) rats | Q44093683 | ||
Lutein, but not alpha-tocopherol, supplementation improves visual function in patients with age-related cataracts: a 2-y double-blind, placebo-controlled pilot study | Q44266631 | ||
A reassessment of protein synthesis by lens nuclear fiber cells | Q44328950 | ||
Vitamin E supplementation in the mitigation of carbon tetrachloride induced oxidative stress in rats | Q44456101 | ||
Molecular identification and cellular localization of a potential transport system involved in cystine/cysteine uptake in human lenses | Q44643048 | ||
Oxygen tension in the rabbit lens and vitreous before and after vitrectomy | Q44820102 | ||
Direct perturbation of lens membrane structure may contribute to cataracts caused by U18666A, an oxidosqualene cyclase inhibitor | Q44854860 | ||
Tryptophan metabolites from young human lenses and the photooxidation of ascorbic acid by UVA light | Q46098756 | ||
Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats | Q46197764 | ||
Revealing anti-inflammatory mechanisms of soy isoflavones by flow: modulation of leukocyte-endothelial cell interactions | Q46417506 | ||
alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells | Q46476357 | ||
Effect of ambroxol, spirulina and vitamin-E in naphthalene induced cataract in female rats | Q46480048 | ||
Coats' disease and bilateral cataract in a child with Turner syndrome: a case report | Q46549630 | ||
Histopathologic findings after treatment with different oxidosqualene cyclase (OSC) inhibitors in hamsters and dogs | Q46642031 | ||
Prevention of selenite-induced cataractogenesis in Wistar rats by the polyphenol, ellagic acid | Q46858843 | ||
Modulation of methylglyoxal and glutathione by soybean isoflavones in mild streptozotocin-induced diabetic rats | Q46865113 | ||
Clinical and radiological findings of a cerebrotendinous xanthomatosis patient with a novel p.A335V mutation in the CYP27A1 gene | Q48436761 | ||
alpha-Crystallin chaperone-like activity and membrane binding in age-related cataracts | Q33989116 | ||
Dietary linolenic acid intake is positively associated with five-year change in eye lens nuclear density | Q34004429 | ||
Detection and prevention of ocular phototoxicity of ciprofloxacin and other fluoroquinolone antibiotics | Q34020997 | ||
Structural and functional roles of deamidation of N146 and/or truncation of NH2- or COOH-termini in human αB-crystallin. | Q34041520 | ||
Coats' disease: a study of 62 histologically confirmed cases | Q34262391 | ||
Recruitment of enzymes and stress proteins as lens crystallins. | Q34330251 | ||
Ageing and vision: structure, stability and function of lens crystallins | Q34339776 | ||
Inhibitory effects of grape seed proanthocyanidin extract on selenite-induced cataract formation and possible mechanism | Q34377516 | ||
Development of a macromolecular diffusion pathway in the lens. | Q34448472 | ||
A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency | Q34478037 | ||
The ether lipid-deficient mouse: tracking down plasmalogen functions | Q34572093 | ||
7-ketocholesterol accumulates in ocular tissues as a consequence of aging and is present in high levels in drusen | Q34624421 | ||
Protection of membrane cholesterol by sphingomyelin against free radical-mediated oxidation | Q34691523 | ||
The ageing lens and cataract: a model of normal and pathological ageing | Q34699914 | ||
Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice | Q34700522 | ||
Cross-linking of lens crystallins in a photodynamic system: a process mediated by singlet oxygen | Q34718189 | ||
α- and β-crystallins modulate the head group order of human lens membranes during aging | Q34735381 | ||
Blind sterile 2 (bs2), a hypomorphic mutation in Agps, results in cataracts and male sterility in mice | Q34851541 | ||
Analysis of concurrent glucose consumption by the hexose monophosphate shunt, glycolysis, and the polyol pathway in the crystalline lens | Q34975199 | ||
Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model | Q35130805 | ||
Lipid domains in intact fiber-cell plasma membranes isolated from cortical and nuclear regions of human eye lenses of donors from different age groups. | Q35155886 | ||
Vitamin C degradation products and pathways in the human lens | Q35423356 | ||
Functions of cholesterol and the cholesterol bilayer domain specific to the fiber-cell plasma membrane of the eye lens. | Q35785790 | ||
Age-related nuclear cataract-oxidation is the key. | Q36111043 | ||
Glutathione-related enzymes and the eye. | Q36371822 | ||
Molecular basis of pH and Ca2+ regulation of aquaporin water permeability | Q36447239 | ||
UV-A-induced structural and functional changes in human lens deamidated alphaB-crystallin. | Q36479056 | ||
The human crystallin gene families | Q36560918 | ||
Carbon turnover in the water-soluble protein of the adult human lens. | Q36634643 | ||
Evolution of crystallins for a role in the vertebrate eye lens. | Q36722216 | ||
The water permeability of lens aquaporin-0 depends on its lipid bilayer environment | Q37166334 | ||
The αA66-80 peptide interacts with soluble α-crystallin and induces its aggregation and precipitation: a contribution to age-related cataract formation | Q37228116 | ||
Oxidative stress, lens gap junctions, and cataracts | Q37285156 | ||
Biological glass: structural determinants of eye lens transparency | Q37852898 | ||
P304 | page(s) | 87-94 | |
P577 | publication date | 2016-03-31 | |
P1433 | published in | Experimental Eye Research | Q15754753 |
P1476 | title | Small molecules, both dietary and endogenous, influence the onset of lens cataracts | |
P478 | volume | 156 |
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Q91609310 | Molecular Processes Implicated in Human Age-Related Nuclear Cataract |
Q55153731 | Non-invasive in vivo quantification of the developing optical properties and graded index of the embryonic eye lens using SPIM. |
Q57802761 | Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers |
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