Hmga2 is required for neural crest cell specification in Xenopus laevis

scientific article published on 21 January 2016

Hmga2 is required for neural crest cell specification in Xenopus laevis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YDBIO.2016.01.014
P698PubMed publication ID26806704

P50authorLuca SimulaQ56384347
Silvia PegoraroQ56409349
Simone MacrìQ56883950
Ilenia PellarinQ56883951
Marco OnoratiQ47698281
P2093author name stringGuidalberto Manfioletti
Riccardo Sgarra
Robert Vignali
P2860cites workAjuba LIM proteins are snail/slug corepressors required for neural crest development in XenopusQ24309249
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transitionQ24318681
CHD7 cooperates with PBAF to control multipotent neural crest formationQ24630725
Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf ExpressionQ24658265
Current perspectives of the signaling pathways directing neural crest inductionQ27024905
Neural crest induction at the neural plate border in vertebratesQ27026327
Epithelial-mesenchymal transitions in development and diseaseQ27860630
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasisQ28131703
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cellsQ28143877
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasisQ28283104
Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-CQ28588994
ADAM 13: a novel ADAM expressed in somitic mesoderm and neural crest cells during Xenopus laevis developmentQ30470157
Use of large-scale expression cloning screens in the Xenopus laevis tadpole to identify gene function.Q30632279
Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development.Q32106979
An NF-kappaB and slug regulatory loop active in early vertebrate mesodermQ33268281
Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transitionQ33411645
Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotypeQ33612796
The architectural transcription factor high mobility group I(Y) participates in photoreceptor-specific gene expression.Q33919538
Molecular biology of HMGA proteins: hubs of nuclear functionQ34095287
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomasQ34135253
A major developmental transition in early Xenopus embryos: II. Control of the onset of transcriptionQ34279768
Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancerQ34347197
Induction of neural crest in Xenopus by transcription factor AP2alphaQ34470119
Reiterative AP2a activity controls sequential steps in the neural crest gene regulatory networkQ34471732
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complexQ34550834
Critical role of the HMGA2 gene in pituitary adenomasQ34565678
Epigenetic regulation in neural crest developmentQ34663839
The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transitionQ34883377
Expression and functional characterization of Xhmg-at-hook genes in Xenopus laevisQ34921467
Hmga2 regulates self-renewal of retinal progenitorsQ34999211
Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transitionQ35558027
Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7bQ48369952
Induction and patterning of the telencephalon in Xenopus laevisQ48459006
Twist function is required for the morphogenesis of the cephalic neural tube and the differentiation of the cranial neural crest cells in the mouse embryoQ48567446
Expression of HMGA2 variants during oogenesis and early embryogenesis of Xenopus laevis.Q50650925
Identification and developmental expression of Xenopus hmga2beta.Q52003335
deltaEF1 and SIP1 are differentially expressed and have overlapping activities during Xenopus embryogenesis.Q52024209
Sox10 regulates the development of neural crest-derived melanocytes in Xenopus.Q52103988
Snail precedes slug in the genetic cascade required for the specification and migration of the Xenopus neural crest.Q52111064
FGF-8 stimulates neuronal differentiation through FGFR-4a and interferes with mesoderm induction in Xenopus embryos.Q52143559
The expression pattern of the Hmgic gene during development.Q52182150
The neural crestQ56907244
Hairy2–Id3 interactions play an essential role in Xenopus neural crest progenitor specificationQ63255985
Misexpression of full-length HMGA2 induces benign mesenchymal tumors in miceQ80050810
Matrix metalloproteinase genes in Xenopus developmentQ80439094
HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genesQ35615694
Transforming growth factor-beta employs HMGA2 to elicit epithelial-mesenchymal transition.Q36118227
An essential role of metalloprotease-disintegrin ADAM12 in triple-negative breast cancerQ36315707
A novel HMGA1-CCNE2-YAP axis regulates breast cancer aggressivenessQ36326335
An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesisQ36821086
Roles of HMGA proteins in cancerQ37001370
HMGA2 is a driver of tumor metastasis.Q37025050
Molecular analysis of neural crest migrationQ37058221
HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cellsQ37150773
HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness.Q37207673
Metalloproteinase-disintegrin ADAM12 is associated with a breast tumor-initiating cell phenotype.Q37352137
HMGA molecular network: From transcriptional regulation to chromatin remodelingQ37592470
HMGA and cancerQ37685437
Neural crest transcription factor Sox10 is preferentially expressed in triple-negative and metaplastic breast carcinomas.Q37689269
The ins and outs of the epithelial to mesenchymal transition in health and diseaseQ37899185
Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migrationQ37977230
The high mobility group protein HMG I(Y) is required for NF-kappa B-dependent virus induction of the human IFN-beta geneQ38324299
Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction.Q38330996
Epigenetic regulation of the miR142-3p/interleukin-6 circuit in glioblastoma.Q39044274
ADAM12 redistributes and activates MMP-14, resulting in gelatin degradation, reduced apoptosis and increased tumor growthQ39100094
LMO4 is an essential cofactor in the Snail2-mediated epithelial-to-mesenchymal transition of neuroblastoma and neural crest cells.Q39194912
Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transitionQ39210896
A crucial role of a high mobility group protein HMGA2 in cardiogenesisQ39990325
Snail-regulated genes in malignant melanomaQ40395148
Expression of Pax-3 in the lateral neural plate is dependent on a Wnt-mediated signal from posterior nonaxial mesodermQ41683443
Snail-related transcriptional repressors are required in Xenopus for both the induction of the neural crest and its subsequent migrationQ41731149
The LIM adaptor protein LMO4 is an essential regulator of neural crest developmentQ41971781
LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program.Q41978713
ADAM13 function is required in the 3 dimensional context of the embryo during cranial neural crest cell migration in Xenopus laevisQ42020839
Histone Demethylase JmjD2A Regulates Neural Crest SpecificationQ42071129
Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group A2 during epithelial-to-mesenchymal transitionQ42119690
A PHD12-Snail2 repressive complex epigenetically mediates neural crest epithelial-to-mesenchymal transitionQ42325939
Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in XenopusQ42953403
The expression of the high-mobility group A2 protein in colorectal cancer and surrounding fibroblasts is linked to tumor invasivenessQ43603420
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crestQ44762736
Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration.Q44882362
Dynamic interaction of HMGA1a proteins with chromatinQ47302322
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAfrican clawed frogQ654718
P304page(s)25-37
P577publication date2016-01-21
P1433published inDevelopmental BiologyQ3025402
P1476titleHmga2 is required for neural crest cell specification in Xenopus laevis
P478volume411

Reverse relations

cites work (P2860)
Q59763028A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices
Q64052248A deficiency in SUMOylation activity disrupts multiple pathways leading to neural tube and heart defects in Xenopus embryos
Q99611756Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration
Q92815312HMGA Genes and Proteins in Development and Evolution
Q92591768MicroRNA-9 exerts antitumor effects on hepatocellular carcinoma progression by targeting HMGA2
Q88173612Proteomic Characterization of the Neural Ectoderm Fated Cell Clones in the Xenopus laevis Embryo by High-Resolution Mass Spectrometry
Q59763033Specifying neural crest cells: From chromatin to morphogens and factors in between
Q42509365The HMGA gene family in chordates: evolutionary perspectives from amphioxus.
Q91811171The Many Faces of Xenopus: Xenopus laevis as a Model System to Study Wolf-Hirschhorn Syndrome
Q99367085Using an aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders

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