Organophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells

scientific article published on 21 January 2016

Organophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/TOXSCI/KFW012
P698PubMed publication ID26794138

P2093author name stringBarbara F Hales
Bernard Robaire
Gauthier Schang
P2860cites workReproductive tract lesions resulting from subchronic administration (63 days) of tri-o-cresyl phosphate in male ratsQ23921706
Testicular toxicity following oral administration of tri-O-cresyl phosphate (TOCP) in roostersQ23921715
Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cellsQ28239151
Polybrominated diphenyl ether (PBDE)-induced alterations in vitamin A and thyroid hormone concentrations in the rat during lactation and early postnatal developmentQ28304866
Molecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cellsQ30495487
House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parametersQ33789881
Relationships between polybrominated diphenyl ether concentrations in house dust and serumQ34051781
Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.Q34263543
Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrationsQ34302805
cAMP regulates P450scc gene expression by a cycloheximide-insensitive mechanism in cultured mouse Leydig MA-10 cellsQ34310833
Persistent organic pollutants including polychlorinated and polybrominated dibenzo-p-dioxins and dibenzofurans in firefighters from Northern California.Q34326997
Serum concentrations of polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyl (PBB) in the United States population: 2003-2004.Q34762990
Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.Q34950954
Children show highest levels of polybrominated diphenyl ethers in a California family of four: a case studyQ35113160
After the PBDE phase-out: a broad suite of flame retardants in repeat house dust samples from CaliforniaQ36474540
Effect of glutathione depletion on Leydig cell steroidogenesis in young and old brown Norway ratsQ36578815
Exposure to flame retardant chemicals on commercial airplanesQ36688893
Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat.Q37358799
Effects of TDCPP or TPP on gene transcriptions and hormones of HPG axis, and their consequences on reproduction in adult zebrafish (Danio rerio).Q38451176
2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) decreases progesterone synthesis through cAMP-PKA pathway and P450scc downregulation in mouse Leydig tumor cellsQ39301745
Effects of di-(2-ethylhexyl) phthalate and four of its metabolites on steroidogenesis in MA-10 cells.Q39413708
Cholesterol movement between the plasma membrane and the cholesteryl ester droplets of cultured Leydig tumour cellsQ42133665
Immunologic and endocrine effects of the flame-retardant pentabromodiphenyl ether (DE-71) in C57BL/6J mice.Q42498982
New details on organophosphate flame retardants: exposure in men appears stable over timeQ43140046
Age-related increase in mitochondrial superoxide generation in the testosterone-producing cells of Brown Norway rat testes: relationship to reduced steroidogenic function?Q43767593
Steroid secretion following exposure of ovarian follicular cells to single congeners and defined mixture of polybrominateddibenzoethers (PBDEs), p,p'-DDT and its metabolite p,p'-DDE.Q46649461
Exposure of male mice to two kinds of organophosphate flame retardants (OPFRs) induced oxidative stress and endocrine disruptionQ46699567
Polybrominated diphenyl ethers in human serum and sperm qualityQ46718688
Characterization of delayed neurotoxicity in the mouse following chronic oral administration of tri-o-cresyl phosphateQ48479108
The relationship between neurological damage and neurotoxic esterase inhibition in rats acutely exposed to tri-ortho-cresyl phosphate.Q48506111
Evaluation of micronuclei induction capacity and mutagenicity of organochlorine and organophosphate pesticidesQ50021372
The effects of chronic high dose androgen or estrogen treatment on the human prostate [corrected]Q50986851
The interaction of Sertoli and Leydig cells in the testicular toxicity of tri-o-cresyl phosphate.Q52240799
N-acetyl cysteine attenuates diazinon exposure-induced oxidative stress in rat testis.Q52739838
P433issue2
P921main subjectorganophosphateQ411097
flame retardantQ902863
P304page(s)499-509
P577publication date2016-01-21
P1433published inToxicological SciencesQ2446966
P1476titleOrganophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells
P478volume150

Reverse relations

cites work (P2860)
Q90017058Associations between urinary organophosphate ester metabolites and measures of adiposity among U.S. children and adults: NHANES 2013-2014
Q48116616Characterization of Individual Isopropylated and tert-Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585.
Q88457316Children's residential exposure to organophosphate ester flame retardants and plasticizers: Investigating exposure pathways in the TESIE study
Q41354120Chlorinated biphenyls effect on estrogen-related receptor expression, steroid secretion, mitochondria ultrastructure but not on mitochondrial membrane potential in Leydig cells
Q36346284Exploring adduct formation between human serum albumin and eleven organophosphate ester flame retardants and plasticizers using MALDI-TOF/TOF and LC-Q/TOF
Q47564958Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization
Q66476446The association between urinary concentrations of phosphorous-containing flame retardant metabolites and semen parameters among men from a fertility clinic

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