Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

scientific article published on 14 January 2016

Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1043656287
P356DOI10.1007/S13277-016-4790-Y
P8608Fatcat IDrelease_i7clxnxugfhbjjrq35dhulhozi
P698PubMed publication ID26768617

P50authorPeter LeungQ56224384
Jung-Chien ChengQ73110519
Vincent T W ChangQ87083275
P2093author name stringCongjian Xu
Jianfang Zhao
Wai-Kin So
Yingtao Liu
P2860cites worksprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airwaysQ24336220
Clinical investigation of receptor and non-receptor tyrosine kinase inhibitors for the treatment of epithelial ovarian cancerQ27024235
Untangling the ErbB signalling networkQ27860884
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?Q29547559
EGF-ERBB signalling: towards the systems levelQ29619032
Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells.Q33637424
The expression of the Sprouty 1 protein inversely correlates with growth, proliferation, migration and invasion of ovarian cancer cellsQ33756953
The developing story of Sprouty and cancerQ33962853
Expression of Sprouty genes 1, 2 and 4 during mouse organogenesisQ34103833
EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells?Q34222070
Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancerQ34481087
The prognostic value of epidermal growth factor receptor mRNA expression in primary ovarian cancerQ36135007
Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.Q36336041
Clinical significance of heparin-binding epidermal growth factor-like growth factor in peritoneal fluid of ovarian cancerQ36616823
Sprouty proteins: modified modulators, matchmakers or missing links?Q37474068
Targeting tyrosine-kinases in ovarian cancerQ38118388
Transforming growth factor-α induces human ovarian cancer cell invasion by down-regulating E-cadherin in a Snail-independent mannerQ38887866
Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasionQ38926129
Amphiregulin induces human ovarian cancer cell invasion by down-regulating E-cadherin expressionQ38952915
Epidermal growth factor induces human oviductal epithelial cell invasion by down-regulating E-cadherin expressionQ39351888
Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells.Q39363770
Sprouty-4 inhibits transformed cell growth, migration and invasion, and epithelial-mesenchymal transition, and is regulated by Wnt7A through PPARgamma in non-small cell lung cancerQ39700563
Bimodal expression of Sprouty2 during the cell cycle is mediated by phase-specific Ras/MAPK and c-Cbl activitiesQ39704810
Validation of HB-EGF and amphiregulin as targets for human cancer therapy.Q40049169
Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activationQ40787356
ERK pathway positively regulates the expression of Sprouty genesQ40789529
The increased Sprouty4 expression in response to serum is transcriptionally controlled by Specific protein 1.Q40957092
Sprouty 2 protein, but not Sprouty 4, is an independent prognostic biomarker for human epithelial ovarian cancerQ41513194
Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed.Q41692233
Atypical role of sprouty in colorectal cancer: sprouty repression inhibits epithelial-mesenchymal transitionQ42333786
Amphiregulin is much more abundantly expressed than transforming growth factor-alpha and epidermal growth factor in human follicular fluid obtained from patients undergoing in vitro fertilization-embryo transferQ48762512
Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling.Q51999726
P433issue7
P921main subjectovarian cancerQ172341
P304page(s)9197-9207
P577publication date2016-01-14
P1433published inTumor BiologyQ15757842
P1476titleSprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells
P478volume37

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cites work (P2860)
Q48559871An updated meta-analysis of the prognostic value of decreased E-cadherin expression in ovarian cancer
Q88548168Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice
Q48095542Knockdown of SPRY4 and SPRY4-IT1 inhibits cell growth and phosphorylation of Akt in human testicular germ cell tumours
Q58617724Oncogenic microRNA-411 promotes lung carcinogenesis by directly targeting suppressor genes SPRY4 and TXNIP
Q37697198Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.
Q42137707Sprouty4 mRNA variants and protein expressions in breast and lung-derived cells.
Q57040103Zeb1 potentiates genome-wide gene transcription with Lef1 to promote glioblastoma cell invasion

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