Next generation sequencing: implications in personalized medicine and pharmacogenomics

scientific article published on 12 April 2016

Next generation sequencing: implications in personalized medicine and pharmacogenomics is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1039/C6MB00115G
P8608Fatcat IDrelease_vjcgxhqsivhcjmr2xnzmqukbcq
P698PubMed publication ID27066891

P50authorMustafa TekinQ58979405
Bahareh RabbaniQ87917631
Hirofumi NakaokaQ95979353
P2093author name stringShahin Akhondzadeh
Nejat Mahdieh
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeQ21183894
The Sequence of the Human GenomeQ22065842
DNA sequencing with chain-terminating inhibitorsQ22066207
Genetic diagnosis by whole exome capture and massively parallel DNA sequencingQ22066282
Structural variation in the human genomeQ22122017
An integrated map of genetic variation from 1,092 human genomesQ22122153
Finishing the euchromatic sequence of the human genomeQ22122488
Genome sequencing in microfabricated high-density picolitre reactorsQ24544260
Genome-wide analysis of transcription factor binding sites based on ChIP-Seq dataQ24595121
A new method for sequencing DNAQ24605576
Clinical assessment incorporating a personal genomeQ24612653
A map of human genome variation from population-scale sequencingQ24617794
VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencingQ24628978
Graphene as a subnanometre trans-electrode membraneQ24630567
Genome-wide maps of chromatin state in pluripotent and lineage-committed cellsQ24632506
CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research NetworkQ24632735
Accurate whole human genome sequencing using reversible terminator chemistryQ24641887
Mapping short DNA sequencing reads and calling variants using mapping quality scoresQ24644612
Genome-wide association study identifies novel breast cancer susceptibility lociQ24645441
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesityQ24650037
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetesQ24652324
Selective aluminum passivation for targeted immobilization of single DNA polymerase molecules in zero-mode waveguide nanostructuresQ24652783
Mammalian social odours: attraction and individual recognitionQ24675952
A haplotype map of the human genomeQ24679827
Genetic variation and the de novo assembly of human genomesQ26786788
Computational and bioinformatics frameworks for next-generation whole exome and genome sequencingQ26859702
An obesity-associated gut microbiome with increased capacity for energy harvestQ27860515
Sequencing technologies - the next generationQ27860568
Comparative analysis of algorithms for next-generation sequencing read alignmentQ42613622
Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patientsQ44351201
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterolQ46902379
Meeting summary: Ethical aspects of whole exome and whole genome sequencing studies (WES/WGS) in rare diseases, Tel Aviv, Israel, January 2013.Q48188602
Genomics. Semiconductors inspire new sequencing technologies.Q51559858
The grand challenge to decipher the cancer proteome.Q51901383
Comparison of next-generation sequencing and mutation-specific platforms in clinical practice.Q53575690
Solexa Ltd.Q53639385
Integration of cytogenetic landmarks into the draft sequence of the human genomeQ55898423
Pharmacogenomics steps toward personalized medicineQ56446183
Nanotechnology: Holes with an edgeQ85008422
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.Q36508365
Adjuvant trastuzumab therapy for HER2-overexpressing breast cancer: what we know and what we still need to learnQ36522424
Metabolic programming in the pathogenesis of insulin resistanceQ36893734
Whole-genome sequencing of Trypanosoma brucei reveals introgression between subspecies that is associated with virulenceQ37105635
Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistanceQ37138662
Correlates of metabolic abnormalities in bipolar I disorder at initiation of acute phase treatmentQ37484086
Identification of immunity-related genes in Ostrinia furnacalis against entomopathogenic fungi by RNA-seq analysisQ37490915
The genetics of quantitative traits: challenges and prospectsQ37544241
Pharmacogenetics of warfarinQ37580929
Pharmacogenetics: implications of race and ethnicity on defining genetic profiles for personalized medicineQ37600573
The Database of Genomic Variants: a curated collection of structural variation in the human genome.Q37661947
Genome-wide association studies in pharmacogenomics.Q37714294
Molecular biomarkers: a US FDA effortQ37734421
Duplication of cervical oesophagus: a case report and review of literaturesQ37790891
Innovation: Metabolomics: the apogee of the omics trilogyQ37995821
Next-generation sequencing: impact of exome sequencing in characterizing Mendelian disordersQ38029472
Challenges in pharmacogeneticsQ38103767
Next-generation sequencing of dried blood spot specimens: a novel approach to HIV drug-resistance surveillanceQ38484839
Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatmentQ39189879
Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failure.Q42227057
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing dataQ27860742
Detection of large-scale variation in the human genomeQ28131803
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphismsQ28203288
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistanceQ28240815
A copy number variation map of the human genomeQ28256361
Human genome sequencing using unchained base reads on self-assembling DNA nanoarraysQ28263829
Metabolic profiles of cancer cellsQ28269762
Large-scale copy number polymorphism in the human genomeQ28273726
A genome-wide association study identifies novel risk loci for type 2 diabetesQ28287727
Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence readsQ28296838
Copy-number variation and association studies of human diseaseQ28307763
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing dataQ29547161
Integrating common and rare genetic variation in diverse human populationsQ29547220
A framework for variation discovery and genotyping using next-generation DNA sequencing dataQ29547262
Next-generation DNA sequencingQ29547447
Human genetic variation and its contribution to complex traitsQ29614580
Personal omics profiling reveals dynamic molecular and medical phenotypesQ29614800
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthmaQ29614903
Exome sequencing as a tool for Mendelian disease gene discoveryQ29615382
DNA methylation and human diseaseQ29615417
Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short readsQ29617402
Hypomethylation distinguishes genes of some human cancers from their normal counterpartsQ29619217
Computational neuroanatomy of speech production.Q30360356
Universal amplification, next-generation sequencing, and assembly of HIV-1 genomesQ30421453
Common variants in the GDF5-UQCC region are associated with variation in human heightQ30435234
Whole genome sequencing highlights genetic changes associated with laboratory domestication of C. elegansQ30478649
Computational repositioning of the anticonvulsant topiramate for inflammatory bowel diseaseQ30526431
High-throughput sequencing of Bacillus anthracis in France: investigating genome diversity and population structure using whole-genome SNP discoveryQ30578286
Diagnostic and prognostic prediction using gene expression profiles in high-dimensional microarray dataQ30883005
Cypiripi: exact genotyping of CYP2D6 using high-throughput sequencing dataQ30971296
Direct comparisons of Illumina vs. Roche 454 sequencing technologies on the same microbial community DNA sampleQ31048918
Imaging cytometry by multiparameter fluorescenceQ33298075
ChIP-seq: using high-throughput sequencing to discover protein-DNA interactionsQ33416643
Challenges of sequencing human genomesQ33592630
Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosisQ33822497
Trastuzumab combined to neoadjuvant chemotherapy in patients with HER2-positive breast cancer: a systematic review and meta-analysisQ33969694
Discovery and preclinical validation of drug indications using compendia of public gene expression dataQ33995422
Therapy and epidemiology of autism--clostridial spores as key elementsQ34007199
Continuous base identification for single-molecule nanopore DNA sequencingQ34016957
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samplesQ34020284
Defective N-oxidation of sparteine in man: A new pharmacogenetic defectQ34053243
Polymorphic hydroxylation of Debrisoquine in man.Q34057031
Rep-Seq: uncovering the immunological repertoire through next-generation sequencing.Q34063790
The genetic architecture of quantitative traitsQ34100924
Metabonomics: a platform for studying drug toxicity and gene functionQ34139125
A window into third-generation sequencingQ34139314
CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: a first step towards subpopulation-specific dosagesQ34352560
The promise of whole-exome sequencing in medical geneticsQ34382912
CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysisQ34394876
Common VKORC1 and GGCX polymorphisms associated with warfarin doseQ34417386
An integrated map of structural variation in 2,504 human genomesQ34496621
Whole-exome sequencing efficiently detects rare mutations in autosomal recessive nonsyndromic hearing lossQ34505663
Pharmacogenetics and antiepileptic drugsQ34558112
Whole-genome re-sequencingQ34571951
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancerQ34631785
Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variabilityQ34652997
Deep sequencing of patient genomes for disease diagnosis: when will it become routine?Q34691675
Molecular mechanisms for genomic disordersQ34762662
Human metabolic phenotype diversity and its association with diet and blood pressure.Q34772005
Comparison of custom capture for targeted next-generation DNA sequencingQ34786626
Interpopulation variation frequency of human inosine 5'-monophosphate dehydrogenase type II (IMPDH2) genetic polymorphisms.Q34870084
Integrated next-generation sequencing and avatar mouse models for personalized cancer treatmentQ35067532
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasisQ35144610
The concept of epigenetics and its role in the development of cardiovascular disease: commentary on "new and emerging theories of cardiovascular disease".Q35798449
Pharmacogenetics - five decades of therapeutic lessons from genetic diversityQ35889619
Bisphenol A alters the development of the rhesus monkey mammary glandQ35991627
Mendelian disorders deserve more attentionQ36420704
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectpharmacogenomicsQ1152227
personalized medicineQ2072214
P304page(s)1818-1830
P577publication date2016-04-12
P1433published inMolecular BioSystemsQ3319467
P1476titleNext generation sequencing: implications in personalized medicine and pharmacogenomics
P478volume12

Reverse relations

cites work (P2860)
Q414633053D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders
Q57152715Biomarkers: paving stones on the road towards the personalized precision medicine for oral squamous cell carcinoma
Q64084978Clinical relevance of circulating molecules in cancer: focus on gastrointestinal stromal tumors
Q48104036CoVaCS: a consensus variant calling system
Q59794799Genomic Interventions in Medicine
Q59806888Highlights on the Application of Genomics and Bioinformatics in the Fight Against Infectious Diseases: Challenges and Opportunities in Africa
Q38626087Human genomics projects and precision medicine
Q91846300Integrated analysis identifies DUSP5 as a novel prognostic indicator for thyroid follicular carcinoma
Q91719511MOSClip: multi-omic and survival pathway analysis for the identification of survival associated gene and modules
Q28584456MalaCards: an amalgamated human disease compendium with diverse clinical and genetic annotation and structured search
Q39324692Molecular approaches to the diagnosis and monitoring of production diseases in pigs.
Q38691180Molecular dynamics investigations of membrane-bound CYP2C19 polymorphisms reveal distinct mechanisms for peripheral variants by long-range effects on the enzymatic activity.
Q91004074New Challenges in Oncology for the Brazilian Private Health Sector: Specialists' Concerns After the ISPOR International Congress in Boston, Massachusetts, 2017
Q47805269Next generation sequencing applications for cardiovascular disease
Q47786696Pharmacogenetics and Pharmacogenomics in Moderate-to-Severe Psoriasis
Q92628483RNA‑seq analyses of antibiotic resistance mechanisms in Serratia marcescens
Q38941642Role of pharmacogenetics in public health and clinical health care: a SWOT analysis
Q38774417SDM: a server for predicting effects of mutations on protein stability
Q60930247SMARTcleaner: identify and clean off-target signals in SMART ChIP-seq analysis
Q54226470Simultaneous sequencing of coding and non-coding RNA reveals a human transcriptome dominated by a small number of highly expressed non-coding genes.
Q48168906Sudden Arrhythmic Death During Exercise: A Post-Mortem Genetic Analysis.
Q47556879Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues.
Q37550834Transcriptome Sequencing of Gynostemma pentaphyllum to Identify Genes and Enzymes Involved in Triterpenoid Biosynthesis
Q38740539Utilizing nutritional genomics to tailor diets for the prevention of cardiovascular disease: a guide for upcoming studies and implementations

Search more.