| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1050481291 |
| P356 | DOI | 10.1007/S12017-016-8394-X |
| P698 | PubMed publication ID | 27103430 |
| P2093 | author name string | Eng-Ang Ling | |
| Yun Yuan | |||
| Ming Fang | |||
| Chun-Yun Wu | |||
| P2860 | cites work | TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease | Q21093232 |
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| Comparative Metabolomic Analysis of the Neuroprotective Effects of Scutellarin and Scutellarein against Ischemic Insult | Q28546284 | ||
| Scutellarin's Cardiovascular Endothelium Protective Mechanism: Important Role of PKG-Iα | Q28550064 | ||
| Expression of Notch-1 receptor and its ligands Jagged-1 and Delta-1 in amoeboid microglia in postnatal rat brain and murine BV-2 cells | Q28581215 | ||
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| Focal cerebral ischemia in the TNFalpha-transgenic rat. | Q33378976 | ||
| Scutellarin exerts its anti-hypertrophic effects via suppressing the Ca2+-mediated calcineurin and CaMKII signaling pathways | Q33522258 | ||
| Scutellarin protects against Aβ-induced learning and memory deficits in rats: involvement of nicotinic acetylcholine receptors and cholinesterase | Q33566782 | ||
| Inflammatory mechanisms in ischemic stroke: role of inflammatory cells | Q33806613 | ||
| Anti-inflammatory effects of Edaravone and Scutellarin in activated microglia in experimentally induced ischemia injury in rats and in BV-2 microglia | Q34584715 | ||
| Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia | Q35047449 | ||
| Astrocytes and stroke: networking for survival? | Q35074272 | ||
| Protective effects of scutellarin on type II diabetes mellitus-induced testicular damages related to reactive oxygen species/Bcl-2/Bax and reactive oxygen species/microcirculation/staving pathway in diabetic rat. | Q35227158 | ||
| Inhibition of nuclear factor kappa B (NF-B): an emerging theme in anti-inflammatory therapies | Q35679402 | ||
| Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats | Q35853281 | ||
| Pathophysiology and therapy of experimental stroke | Q36482587 | ||
| Transformation of amoeboid microglial cells into microglia in the corpus callosum of the postnatal rat brain. An electron microscopical study | Q36496705 | ||
| Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia | Q36516922 | ||
| Microglia in cerebral ischemia: molecular actions and interactions | Q36538353 | ||
| Inflammation in stroke and focal cerebral ischemia. | Q36578756 | ||
| A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion | Q36604211 | ||
| Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage | Q36677396 | ||
| The inflammatory response in stroke | Q36692346 | ||
| Systemic inflammation exacerbates behavioral and histopathological consequences of isolated traumatic brain injury in rats | Q36731635 | ||
| Microglial CD14 activated by iNOS contributes to neuroinflammation in cerebral ischemia | Q36736059 | ||
| Microglial activation and its implications in the brain diseases. | Q36822646 | ||
| Effects of scutellarin on apoptosis induced by cobalt chloride in PC12 cells. | Q46622581 | ||
| Proliferating resident microglia after focal cerebral ischaemia in mice | Q48199281 | ||
| MRI monitoring of neuroinflammation in mouse focal ischemia. | Q48361026 | ||
| Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke. | Q48551433 | ||
| Neuroprotective effects of scutellarin against hypoxic-ischemic-induced cerebral injury via augmentation of antioxidant defense capacity | Q48721782 | ||
| Microglia protect neurons against ischemia by synthesis of tumor necrosis factor. | Q48767062 | ||
| Tumor necrosis factor-alpha neutralization reduced cerebral edema through inhibition of matrix metalloproteinase production after transient focal cerebral ischemia | Q49021460 | ||
| Neuroprotective effects of scutellarin and scutellarein on repeatedly cerebral ischemia-reperfusion in rats. | Q50695859 | ||
| Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. | Q52088310 | ||
| A new and efficient synthesis of 6-O-methylscutellarein, the major metabolite of the natural medicine scutellarin. | Q53216907 | ||
| Vascular inflammatory, oxidative and protease-based processes: implications for neuronal cell death in Alzheimer's disease. | Q53263153 | ||
| [The beta-amyloid cascade hypothesis: a sequence of events leading to neurodegeneration in Alzheimer's disease]. | Q53265708 | ||
| Brain macrophages: evaluation of microglia and their functions | Q68222913 | ||
| Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice | Q73315270 | ||
| Quantitative changes in interleukin proteins following focal stroke in the rat | Q73549222 | ||
| Scutellarin blocks sodium current in freshly isolated mouse hippocampal CA1 neurons | Q83460093 | ||
| Acute and subacute toxicological evaluation of scutellarin in rodents | Q83554255 | ||
| Scutellarin-induced apoptosis in HepG2 hepatocellular carcinoma cells via a STAT3 pathway | Q85564442 | ||
| Functional Recovery after Scutellarin Treatment in Transient Cerebral Ischemic Rats: A Pilot Study with (18) F-Fluorodeoxyglucose MicroPET. | Q36861375 | ||
| Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke | Q36875714 | ||
| Notch and NFkappaB signaling pathways: Do they collaborate in normal vertebrate brain development and function? | Q36944897 | ||
| Interleukin-1 and inflammatory neurodegeneration | Q36979642 | ||
| Tumor necrosis factor-alpha potentiates intraneuronal Ca2+ signaling via regulation of the inositol 1,4,5-trisphosphate receptor | Q36981009 | ||
| Delayed neural network degeneration after neonatal hypoxia-ischemia | Q37019522 | ||
| Debris clearance by microglia: an essential link between degeneration and regeneration. | Q37092476 | ||
| Scutellarin attenuates hypertension-induced expression of brain Toll-like receptor 4/nuclear factor kappa B. | Q37239794 | ||
| Phagocytosis executes delayed neuronal death after focal brain ischemia | Q37255890 | ||
| Post-ischemic brain damage: pathophysiology and role of inflammatory mediators. | Q37352179 | ||
| Injury and repair mechanisms in ischemic stroke: considerations for the development of novel neurotherapeutics. | Q37541913 | ||
| Interleukin-6, a mental cytokine. | Q37828952 | ||
| Heterogeneity in the penumbra | Q37897922 | ||
| Notch signaling in the central nervous system with special reference to its expression in microglia | Q38139116 | ||
| Determination of aglycone conjugated metabolites of scutellarin in rat plasma by HPLC. | Q38512909 | ||
| In vitro inhibitory effects of scutellarin on six human/rat cytochrome P450 enzymes and P-glycoprotein. | Q38997725 | ||
| Scutellarin and caffeic acid ester fraction, active components of Dengzhanxixin injection, upregulate neurotrophins synthesis and release in hypoxia/reoxygenation rat astrocytes | Q39098865 | ||
| Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin | Q39172809 | ||
| N9 microglial cells polarized by LPS and IL4 show differential responses to secondary environmental stimuli | Q39250352 | ||
| Novel function of scutellarin in inhibiting cell proliferation and inducing cell apoptosis of human Burkitt lymphoma Namalwa cells | Q39348753 | ||
| Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells | Q39468269 | ||
| Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia. | Q39510849 | ||
| Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation | Q39552093 | ||
| Nuclear factor-κB/p65 responds to changes in the Notch signaling pathway in murine BV-2 cells and in amoeboid microglia in postnatal rats treated with the γ-secretase complex blocker DAPT. | Q39677488 | ||
| Estrogenic and neuroprotective properties of scutellarin from Erigeron breviscapus: a drug against postmenopausal symptoms and Alzheimer's disease | Q39836986 | ||
| Na+ channels as targets for neuroprotective drugs | Q40372481 | ||
| The origin and nature of ramified and amoeboid microglia: a historical review and current concepts | Q40870421 | ||
| TGFβ signalling plays an important role in IL4-induced alternative activation of microglia | Q41508902 | ||
| Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as "continuum" phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain | Q42150350 | ||
| Microglia expressing interleukin-13 undergo cell death and contribute to neuronal survival in vivo | Q42459118 | ||
| Scutellarin inhibits high glucose-induced and hypoxia-mimetic agent-induced angiogenic effects in human retinal endothelial cells through reactive oxygen species/hypoxia-inducible factor-1α/vascular endothelial growth factor pathway | Q42704282 | ||
| Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation | Q43297203 | ||
| Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain. | Q43489000 | ||
| Effects of cortical ischemia and postischemic environmental enrichment on hippocampal cell genesis and differentiation in the adult rat. | Q44079761 | ||
| Protection against hydrogen peroxide-induced cytotoxicity in PC12 cells by scutellarin | Q44820024 | ||
| Suppression of diet-induced hypercholesterolemia by scutellarin in rats | Q44917495 | ||
| Effect of scutellarin on nitric oxide production in early stages of neuron damage induced by hydrogen peroxide | Q45231763 | ||
| Protective effects of scutellarin against cerebral ischemia in rats: evidence for inhibition of the apoptosis-inducing factor pathway | Q46230272 | ||
| Blockade of microglial glutamate release protects against ischemic brain injury | Q46385482 | ||
| The neurotoxicity of β-amyloid peptide toward rat brain is associated with enhanced oxidative stress, inflammation and apoptosis, all of which can be attenuated by scutellarin | Q46436597 | ||
| P433 | issue | 3 | |
| P921 | main subject | neuronitis | Q17157137 |
| cerebral infarction | Q1209150 | ||
| microglia | Q1622829 | ||
| P304 | page(s) | 264-273 | |
| P577 | publication date | 2016-04-21 | |
| P1433 | published in | NeuroMolecular Medicine | Q15716731 |
| P1476 | title | Scutellarin as a Potential Therapeutic Agent for Microglia-Mediated Neuroinflammation in Cerebral Ischemia | |
| P478 | volume | 18 |
| Q42220056 | Anti-Inflammatory and Neuroprotective Effects of Co-UltraPEALut in a Mouse Model of Vascular Dementia. |
| Q64120878 | Anti-inflammatory Effects of Traditional Chinese Medicines on Preclinical Models of Brain Ischemia-Reperfusion-Injury: Prospects for Neuroprotective Drug Discovery and Therapy |
| Q51182174 | CDK11p58 Promotes Microglia Activation via Inducing Cyclin D3 Nuclear Localization. |
| Q64055046 | Effect of Inflammation on the Process of Stroke Rehabilitation and Poststroke Depression |
| Q47891467 | Effect of Scutellarin inhibits collagen‑induced arthritis through TLR4/NF‑κB‑mediated inflammation |
| Q88417394 | Histone Deacetylase 2 Inhibitor CAY10683 Alleviates Lipopolysaccharide Induced Neuroinflammation Through Attenuating TLR4/NF-κB Signaling Pathway |
| Q55074318 | Isolation and characterization of a multifunctional flavonoid glycosyltransferase from Ornithogalum caudatum with glycosidase activity. |
| Q41051944 | Molecular mechanisms underlying the involvement of the sigma-1 receptor in methamphetamine-mediated microglial polarization. |
| Q47117360 | Production of proinflammatory mediators in activated microglia is synergistically regulated by Notch-1, glycogen synthase kinase (GSK-3β) and NF-κB/p65 signalling. |
| Q49195429 | Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis |
| Q88431770 | Scutellarin suppresses neuroinflammation via the inhibition of the AKT/NF-κB and p38/JNK pathway in LPS-induced BV-2 microglial cells |
| Q93148234 | Scutellarin-treated exosomes increase claudin 5, occludin and ZO1 expression in rat brain microvascular endothelial cells |
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