Effect of roflumilast on airway remodelling in a murine model of chronic asthma

scientific article published on 5 November 2015

Effect of roflumilast on airway remodelling in a murine model of chronic asthma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/CEA.12670
P698PubMed publication ID26542330

P50authorSoon S KwonQ56993418
Chin Kook RheeQ40351138
P2093author name stringS Y Lee
J H Kim
Y K Kim
S W Kim
C K Park
T J Kim
H K Yoon
P2860cites workPathology of asthmaQ57901630
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Asthma. From bronchoconstriction to airways inflammation and remodelingQ33915771
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Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjectsQ35560440
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Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPDQ36169173
Eosinophil activation of fibroblasts from chronic allergen-induced disease utilizes stem cell factor for phenotypic changesQ36357396
Airway modeling and remodeling in the pathogenesis of asthmaQ37054846
Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling.Q37071840
Effect of aging on airway remodeling and muscarinic receptors in a murine acute asthma modelQ37245517
The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary diseaseQ37728398
Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease.Q38077614
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Theophylline for COPD.Q42764447
Local administration of antisense phosphorothioate oligonucleotides to the c-kit ligand, stem cell factor, suppresses airway inflammation and IL-4 production in a murine model of asthmaQ42832073
The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthmaQ43873557
Inhibition of inflammation and remodeling by roflumilast and dexamethasone in murine chronic asthmaQ44572920
Inhibition of stem cell factor reduces pulmonary cytokine levels during allergic airway responsesQ44805067
Treatment of cockroach allergen asthma model with imatinib attenuates airway responsesQ45063930
The expression of stem cell factor and c-kit receptor in human asthmatic airwaysQ47346396
TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis.Q51695315
Effect of nilotinib on airway remodeling in a murine model of chronic asthma.Q53054357
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Persistent airway hyperresponsiveness and histologic alterations after chronic antigen challenge in cats.Q54185709
P433issue5
P921main subjectmurine modelQ122890741
P304page(s)754-763
P577publication date2015-11-05
P1433published inClinical & Experimental AllergyQ5133747
P1476titleEffect of roflumilast on airway remodelling in a murine model of chronic asthma
P478volume46

Reverse relations

cites work (P2860)
Q42287278Co-inhalation of roflumilast, rather than formoterol, with fluticasone more effectively improves asthma in asthmatic mice.
Q45070970Developments in the field of allergy in 2016 through the eyes of Clinical and Experimental Allergy
Q50002026Dose dependent effects of tadalafil and roflumilast on ovalbumin-induced airway hyperresponsiveness in guinea pigs
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Q36252920New and developing non-adrenoreceptor small molecule drugs for the treatment of asthma
Q38756064Novel approaches to the management of noneosinophilic asthma
Q58806313Pharmacological mechanism of roflumilast in the treatment of asthma-COPD overlap
Q42368264Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice
Q58606499Phosphodiesterase-4 Inhibitors for the Treatment of Inflammatory Diseases
Q90103145Risk Factors for Acute Exacerbations in Elderly Asthma: What Makes Asthma in Older Adults Distinctive?
Q90048297Role of phosphodiesterase-4 inhibitors in chronic obstructive pulmonary disease

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