review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1152/AJPRENAL.00348.2015 |
P698 | PubMed publication ID | 27147674 |
P50 | author | Henry Krum | Q82083581 |
P2093 | author name string | Andrew R Kompa | |
Suree Lekawanvijit | |||
P2860 | cites work | Role of Gut-Derived Protein-Bound Uremic Toxins in Cardiorenal Syndrome and Potential Treatment Modalities | Q26783196 |
Cardiorenal syndrome: the emerging role of protein-bound uremic toxins | Q26830674 | ||
Cystatin C as a marker of GFR--history, indications, and future research | Q28298855 | ||
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites | Q29619788 | ||
Chronic kidney disease-induced cardiac fibrosis is ameliorated by reducing circulating levels of a non-dialysable uremic toxin, indoxyl sulfate | Q31076633 | ||
Carcinogenesis studies of cresols in rats and mice | Q33677149 | ||
p-Cresol and cardiovascular risk in mild-to-moderate kidney disease | Q33944858 | ||
Novel method for simultaneous determination of p-cresylsulphate and p-cresylglucuronide: clinical data and pathophysiological implications | Q34100425 | ||
Uremic toxins induce kidney fibrosis by activating intrarenal renin-angiotensin-aldosterone system associated epithelial-to-mesenchymal transition | Q34221944 | ||
Podocyte injury caused by indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand | Q34227115 | ||
Galacto-oligosaccharides attenuate renal injury with microbiota modification | Q34297383 | ||
Indoxyl Sulfate–Induced Endothelial Dysfunction in Patients with Chronic Kidney Disease via an Induction of Oxidative Stress | Q34497254 | ||
p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease | Q34593224 | ||
An update on uremic toxins | Q34641464 | ||
Uremia | Q34693851 | ||
The uremic toxin adsorbent AST-120 abrogates cardiorenal injury following myocardial infarction | Q35071066 | ||
Colonic contribution to uremic solutes. | Q35210230 | ||
Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice | Q35466116 | ||
Gas chromatographic-mass spectrometric analysis for measurement of p-cresol and its conjugated metabolites in uremic and normal serum. | Q46616212 | ||
Indoxyl sulfate reduces superoxide scavenging activity in the kidneys of normal and uremic rats | Q46832073 | ||
Oral sorbent AST-120 increases renal NO synthesis in uremic rats | Q46843782 | ||
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients. | Q46900369 | ||
Indoxyl sulfate induces complex redox alterations in mesangial cells | Q46910093 | ||
P-cresylsulphate, the main in vivo metabolite of p-cresol, activates leucocyte free radical production | Q49168516 | ||
p-Cresol sulfate and indoxyl sulfate induce similar cellular inflammatory gene expressions in cultured proximal renal tubular cells. | Q51366095 | ||
Independent components of chronic kidney disease as a cardiovascular risk state: results from the Kidney Early Evaluation Program (KEEP). | Q51750503 | ||
Indoxyl sulfate stimulates proliferation of rat vascular smooth muscle cells. | Q53627736 | ||
Indoxyl sulfate, a uremic toxin, promotes cell senescence in aorta of hypertensive rats | Q54657758 | ||
Indoxyl sulfate induces IL-6 expression in vascular endothelial and smooth muscle cells through OAT3-mediated uptake and activation of AhR/NF-κB pathway. | Q55070323 | ||
Alteration of the Intestinal Environment by Lubiprostone Is Associated with Amelioration of Adenine-Induced CKD. | Q35530569 | ||
Contribution of microRNA to pathological fibrosis in cardio-renal syndrome: impact of uremic toxins | Q35588665 | ||
Randomized Placebo-Controlled EPPIC Trials of AST-120 in CKD. | Q35790521 | ||
Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation. | Q35835293 | ||
p-Cresyl sulfate aggravates cardiac dysfunction associated with chronic kidney disease by enhancing apoptosis of cardiomyocytes | Q36141979 | ||
Molecular mechanisms and therapeutic strategies of chronic renal injury: the role of nuclear factor kappaB activation in the development of renal fibrosis | Q36362308 | ||
Protein-bound uremic toxins stimulate crosstalk between leukocytes and vessel wall | Q37340172 | ||
Serum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients | Q37378435 | ||
Kidney injury molecule-1 in renal disease | Q37634474 | ||
Effect of short-term synbiotic treatment on plasma p-cresol levels in patients with chronic renal failure: a randomized clinical trial. | Q38428422 | ||
Uremic toxin p-cresol induces disassembly of gap junctions of cardiomyocytes | Q39311803 | ||
NF-κB plays an important role in indoxyl sulfate-induced cellular senescence, fibrotic gene expression, and inhibition of proliferation in proximal tubular cells | Q39492071 | ||
Effect of repeated oral administrations of the oral adsorbent AST-120 on serum creatinine and other markers of renal function. A randomized controlled study in patients with chronic kidney disease | Q40341418 | ||
Role of organic anion transporters in the tubular transport of indoxyl sulfate and the induction of its nephrotoxicity | Q40721603 | ||
Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts | Q41931102 | ||
Indoxyl sulfate downregulates renal expression of Klotho through production of ROS and activation of nuclear factor-ĸB. | Q42746597 | ||
Indoxyl Sulfate Stimulates Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells by Inducing Oxidative Stress Through Activation of the NADPH Oxidase-Nuclear Factor-.KAPPA.B Pathway | Q42917319 | ||
Pilot study of probiotic dietary supplementation for promoting healthy kidney function in patients with chronic kidney disease | Q42933107 | ||
Cost-effectiveness of administering oral adsorbent AST-120 to patients with diabetes and advance-stage chronic kidney disease | Q42937685 | ||
Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes? | Q43202700 | ||
Free p-cresylsulphate is a predictor of mortality in patients at different stages of chronic kidney disease | Q43241952 | ||
p-Cresyl sulfate serum concentrations in haemodialysis patients are reduced by the prebiotic oligofructose-enriched inulin. | Q43289498 | ||
Effects of synbiotic treatment on serum level of p-cresol in haemodialysis patients: a preliminary study | Q43321758 | ||
Association between AST-120 and abdominal aortic calcification in predialysis patients with chronic kidney disease | Q43461034 | ||
Renal function as a predictor of outcome in a broad spectrum of patients with heart failure | Q43500856 | ||
Oral charcoal adsorbent (AST-120) prevents progression of cardiac damage in chronic kidney disease through suppression of oxidative stress | Q43609975 | ||
Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. | Q43683472 | ||
Serum indoxyl sulfate levels in patients with diabetic nephropathy: relation to renal function | Q43959918 | ||
P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines | Q44213000 | ||
Effects of the oral adsorbent AST-120 on tryptophan metabolism in uremic patients | Q44337949 | ||
Bifidobacterium in gastro-resistant seamless capsule reduces serum levels of indoxyl sulfate in patients on hemodialysis | Q44338020 | ||
Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells | Q44390483 | ||
Very low protein diet reduces indoxyl sulfate levels in chronic kidney disease | Q44527821 | ||
Protein restriction and AST-120 improve lipoprotein lipase and VLDL receptor in focal glomerulosclerosis | Q44609801 | ||
Evidence for impaired assimilation of protein in chronic renal failure | Q44665693 | ||
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair | Q44724729 | ||
Oral ADSORBENT AST-120 decreases carotid intima-media thickness and arterial stiffness in patients with chronic renal failure | Q44820468 | ||
Protective effect of an oral adsorbent on renal function in chronic renal failure: determinants of its efficacy in diabetic nephropathy | Q44904214 | ||
Effect of a carbonaceous oral adsorbent on the progression of CKD: a multicenter, randomized, controlled trial. | Q45926202 | ||
The uremic retention solute p-cresyl sulfate and markers of endothelial damage. | Q45926204 | ||
Long-term effects of the oral adsorbent, AST-120, in patients with chronic renal failure | Q46122815 | ||
Indoxyl sulphate induces oxidative stress and the expression of osteoblast-specific proteins in vascular smooth muscle cells. | Q46150965 | ||
Urinary neutrophil gelatinase-associated lipocalin levels reflect damage to glomeruli, proximal tubules, and distal nephrons | Q46160566 | ||
Activation of aryl hydrocarbon receptor mediates indoxyl sulfate-induced monocyte chemoattractant protein-1 expression in human umbilical vein endothelial cells | Q46536842 | ||
Long-term prognosis of acute kidney injury after acute myocardial infarction | Q46599330 | ||
P433 | issue | 1 | |
P921 | main subject | oversight | Q60697989 |
P304 | page(s) | F52-62 | |
P577 | publication date | 2016-05-04 | |
P1433 | published in | American Journal of Physiology - Renal Physiology | Q2610177 |
P1476 | title | Protein-bound uremic toxins: a long overlooked culprit in cardiorenal syndrome | |
P478 | volume | 311 |