| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/978-3-319-26974-0_5 |
| P698 | PubMed publication ID | 27161226 |
| P2093 | author name string | Indu S Ambudkar | |
| Hwei Ling Ong | |||
| Lorena Brito de Souza | |||
| P2860 | cites work | Modulation of Ca(2+) entry by polypeptides of the inositol 1,4, 5-trisphosphate receptor (IP3R) that bind transient receptor potential (TRP): evidence for roles of TRP and IP3R in store depletion-activated Ca(2+) entry | Q22010985 |
| Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors | Q24295021 | ||
| Orai1 is an essential pore subunit of the CRAC channel | Q24300383 | ||
| STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels | Q24304975 | ||
| STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx | Q24307461 | ||
| TRPC1, a human homolog of a Drosophila store-operated channel | Q24312092 | ||
| trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry | Q24314989 | ||
| STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1 | Q24315782 | ||
| Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells | Q24321234 | ||
| Subunit composition of mammalian transient receptor potential channels in living cells | Q24530559 | ||
| Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity | Q24548526 | ||
| Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components | Q24612969 | ||
| STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels | Q24643529 | ||
| STIM1, an essential and conserved component of store-operated Ca2+ channel function | Q24678317 | ||
| Plasma membrane localization and function of TRPC1 is dependent on its interaction with beta-tubulin in retinal epithelium cells | Q39668947 | ||
| Functional interactions among STIM1, Orai1 and TRPC1 on the activation of SOCs in HL-7702 cells | Q39765265 | ||
| Regulation of TRPC1 and TRPC4 cation channels requires an alpha1-syntrophin-dependent complex in skeletal mouse myotubes. | Q39790252 | ||
| Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1. | Q39882050 | ||
| TRPC1 regulates skeletal myoblast migration and differentiation | Q39918781 | ||
| Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. | Q40026601 | ||
| Biochemical and functional characterization of Orai proteins | Q40172328 | ||
| CRACM1 multimers form the ion-selective pore of the CRAC channel. | Q40231288 | ||
| Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells | Q40258558 | ||
| Regulation of store-operated calcium entries and mitochondrial uptake by minidystrophin expression in cultured myotubes | Q40357297 | ||
| Distinct Ca(2+)-permeable cation currents are activated by internal Ca(2+)-store depletion in RBL-2H3 cells and human salivary gland cells, HSG and HSY. | Q40497039 | ||
| A TRPC1/TRPC3-mediated increase in store-operated calcium entry is required for differentiation of H19-7 hippocampal neuronal cells | Q40527910 | ||
| Human TRPC5 channel activated by a multiplicity of signals in a single cell | Q40535856 | ||
| Expression level of the canonical transient receptor potential 3 (TRPC3) channel determines its mechanism of activation | Q40657183 | ||
| Selective association of TRPC channel subunits in rat brain synaptosomes | Q40697831 | ||
| Trp1, a candidate protein for the store-operated Ca(2+) influx mechanism in salivary gland cells | Q40903218 | ||
| Gated regulation of CRAC channel ion selectivity by STIM1. | Q40999366 | ||
| STIM1 and STIM2 proteins differently regulate endogenous store-operated channels in HEK293 cells. | Q41657816 | ||
| Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx. | Q41897197 | ||
| An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry | Q41968043 | ||
| ATP depletion induces translocation of STIM1 to puncta and formation of STIM1-ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP. | Q42110439 | ||
| Role of TRPC1 and TRPC3 channels in contraction and relaxation of mouse thoracic aorta | Q42116750 | ||
| Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel | Q42222477 | ||
| Translocation between PI(4,5)P2-poor and PI(4,5)P2-rich microdomains during store depletion determines STIM1 conformation and Orai1 gating | Q42619655 | ||
| Lipid rafts modulate the activation but not the maintenance of store-operated Ca(2+) entry. | Q42988620 | ||
| Expression and association of TRPC subtypes with Orai1 and STIM1 in human parathyroid | Q43145636 | ||
| STIM1, Orai1 and hTRPC1 are important for thrombin- and ADP-induced aggregation in human platelets. | Q43288918 | ||
| Endogenously expressed Trp1 is involved in store-mediated Ca2+ entry by conformational coupling in human platelets | Q44114999 | ||
| TRPC1 is required for functional store-operated Ca2+ channels. Role of acidic amino acid residues in the S5-S6 region. | Q44283756 | ||
| Capacitative calcium entry and TRPC channel proteins are expressed in rat distal pulmonary arterial smooth muscle | Q44691480 | ||
| A role for hTRPC1 and lipid raft domains in store-mediated calcium entry in human platelets | Q44714247 | ||
| A role for SNAP-25 but not VAMPs in store-mediated Ca2+ entry in human platelets. | Q44879652 | ||
| ATP-induced mitogenesis is mediated by cyclic AMP response element-binding protein-enhanced TRPC4 expression and activity in human pulmonary artery smooth muscle cells | Q44960170 | ||
| During post-natal human myogenesis, normal myotube size requires TRPC1- and TRPC4-mediated Ca²⁺ entry. | Q45282418 | ||
| Characteristics of transient receptor potential canonical calcium-permeable channels and their relevance to vascular physiology and disease | Q27010256 | ||
| STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction | Q28115928 | ||
| RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability | Q28206364 | ||
| STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels | Q28257477 | ||
| Functional interaction between InsP3 receptors and store-operated Htrp3 channels | Q28291524 | ||
| A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function | Q28305026 | ||
| Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice | Q28510773 | ||
| Formation of novel TRPC channels by complex subunit interactions in embryonic brain | Q28568573 | ||
| Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity | Q28593398 | ||
| Role of lipid rafts in the interaction between hTRPC1, Orai1 and STIM1 | Q28614727 | ||
| TRP channels | Q29616673 | ||
| Store-operated calcium channels | Q29617459 | ||
| Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1. | Q30492038 | ||
| TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells | Q30516435 | ||
| Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice | Q31929609 | ||
| Role of TRPC1 channel in skeletal muscle function | Q33589307 | ||
| TRPC3 regulates agonist-stimulated Ca2+ mobilization by mediating the interaction between type I inositol 1,4,5-trisphosphate receptor, RACK1, and Orai1 | Q33707020 | ||
| Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry | Q33814695 | ||
| Molecular basis of calcium signaling in lymphocytes: STIM and ORAI | Q33819323 | ||
| Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions | Q33847729 | ||
| TRPC channels are necessary mediators of pathologic cardiac hypertrophy | Q33859656 | ||
| TRPC4 knockdown suppresses epidermal growth factor-induced store-operated channel activation and growth in human corneal epithelial cells | Q33896548 | ||
| TRPC1 channels are critical for hypertrophic signaling in the heart | Q33896913 | ||
| Molecular cloning of a widely expressed human homologue for the Drosophila trp gene | Q34297844 | ||
| STIM1-dependent and STIM1-independent Function of Transient Receptor Potential Canonical (TRPC) Channels Tunes Their Store-operated Mode | Q34352403 | ||
| Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells | Q34428327 | ||
| Distinct contributions of Orai1 and TRPC1 to agonist-induced [Ca(2+)](i) signals determine specificity of Ca(2+)-dependent gene expression | Q34463485 | ||
| Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells. | Q34493914 | ||
| TRP channel proteins and signal transduction | Q34578739 | ||
| Caveolin-1 enhances rapid mucosal restitution by activating TRPC1-mediated Ca2+ signaling | Q34631892 | ||
| Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels | Q34759760 | ||
| Classical Transient Receptor Potential 1 (TRPC1): Channel or Channel Regulator? | Q34774691 | ||
| Genetic and pharmacologic inhibition of the Ca2+ influx channel TRPC3 protects secretory epithelia from Ca2+-dependent toxicity. | Q35028058 | ||
| Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P₂ between distinct membrane pools | Q35112295 | ||
| Regulation of calcium influx by second messengers in rat mast cells. | Q45863546 | ||
| Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains. | Q45866800 | ||
| TRPC1 and STIM1 mediate capacitative Ca2+ entry in mouse pulmonary arterial smooth muscle cells | Q46068670 | ||
| Interaction between TRPC1/TRPC4 assembly and STIM1 contributes to store-operated Ca2+ entry in mesangial cells. | Q46078178 | ||
| Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways. | Q46100660 | ||
| Role of Trpc channels, Stim1 and Orai1 in PGF(2α)-induced calcium signaling in NRK fibroblasts | Q46405256 | ||
| Molecular cloning and functional characterization of a novel receptor-activated TRP Ca2+ channel from mouse brain | Q48037830 | ||
| Combined single channel and single molecule detection identifies subunit composition of STIM1-activated transient receptor potential canonical (TRPC) channels. | Q50444240 | ||
| Positive regulation of capacitative Ca2+ entry by intracellular Ca2+ in Xenopus oocytes expressing rat TRP4. | Q50722810 | ||
| The store-operated calcium current I(CRAC): nonlinear activation by InsP3 and dissociation from calcium release. | Q52262061 | ||
| Second messenger-activated calcium influx in rat peritoneal mast cells. | Q54104148 | ||
| Evidence that TRPC4 supports the calcium selective I(CRAC)-like current in human gingival keratinocytes. | Q54577159 | ||
| Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability | Q74452970 | ||
| Phenotype of a recombinant store-operated channel: highly selective permeation of Ca2+ | Q78040183 | ||
| Interaction of STIM1 with endogenously expressed human canonical TRP1 upon depletion of intracellular Ca2+ stores | Q79998854 | ||
| Canonical transient receptor potential 1 channel is involved in contractile function of glomerular mesangial cells | Q80050764 | ||
| Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells | Q82285456 | ||
| Lipid rafts are essential for the regulation of SOCE by plasma membrane resident STIM1 in human platelets | Q83263825 | ||
| TRPC1. | Q38206420 | ||
| TRPC2. | Q38206421 | ||
| TRPC3: a multifunctional signaling molecule. | Q38206422 | ||
| TRPC4- and TRPC4-containing channels | Q38206423 | ||
| TRPC5. | Q38206424 | ||
| TRPC6: physiological function and pathophysiological relevance | Q38206425 | ||
| Physiological functions and regulation of TRPC channels | Q38222951 | ||
| The TRPCs-STIM1-Orai interaction. | Q38222952 | ||
| Structural and functional mechanisms of CRAC channel regulation | Q38256949 | ||
| Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3. | Q38327904 | ||
| Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site | Q38885774 | ||
| Mechanosensitive store-operated calcium entry regulates the formation of cell polarity. | Q38914426 | ||
| STIM1 regulates TRPC6 heteromultimerization and subcellular location. | Q38969078 | ||
| Coordinated oscillations in cortical actin and Ca2+ correlate with cycles of vesicle secretion | Q39246519 | ||
| Electrophysiological properties of heteromeric TRPV4-C1 channels. | Q39483608 | ||
| STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions. | Q35240454 | ||
| The dynamic complexity of the TRPC1 channelosome | Q35592091 | ||
| Orai proteins interact with TRPC channels and confer responsiveness to store depletion. | Q35721728 | ||
| Heteromeric canonical transient receptor potential 1 and 4 channels play a critical role in epileptiform burst firing and seizure-induced neurodegeneration | Q35776768 | ||
| The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells | Q35846857 | ||
| Trpc1 ion channel modulates phosphatidylinositol 3-kinase/Akt pathway during myoblast differentiation and muscle regeneration. | Q35922471 | ||
| Different agonists recruit different stromal interaction molecule proteins to support cytoplasmic Ca2+ oscillations and gene expression | Q35935758 | ||
| Polyamines regulate intestinal epithelial restitution through TRPC1-mediated Ca²+ signaling by differentially modulating STIM1 and STIM2. | Q36175731 | ||
| Emerging functions of 10 types of TRP cationic channel in vascular smooth muscle | Q36239738 | ||
| Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels | Q36498394 | ||
| Cation channels of the transient receptor potential superfamily: their role in physiological and pathophysiological processes of smooth muscle cells. | Q36536869 | ||
| Ca2+ signaling, TRP channels, and endothelial permeability | Q36645346 | ||
| Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE) | Q36719287 | ||
| Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1 | Q36731463 | ||
| Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1. | Q36752210 | ||
| Organization and function of TRPC channelosomes | Q36814439 | ||
| Transient receptor potential canonical 7: a diacylglycerol-activated non-selective cation channel | Q36817594 | ||
| TRPC1 regulates calcium-activated chloride channels in salivary gland cells | Q36915868 | ||
| Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane | Q36976158 | ||
| Canonical transient receptor potential channel (TRPC)3 and TRPC6 associate with large-conductance Ca2+-activated K+ (BKCa) channels: role in BKCa trafficking to the surface of cultured podocytes | Q37104933 | ||
| A role for Orai in TRPC-mediated Ca2+ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca2+ entry. | Q37117639 | ||
| SOAR and the polybasic STIM1 domains gate and regulate Orai channels | Q37145533 | ||
| Canonical transient receptor potential 5 channel in conjunction with Orai1 and STIM1 allows Sr2+ entry, optimal influx of Ca2+, and degranulation in a rat mast cell line | Q37189697 | ||
| Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cells | Q37283364 | ||
| A TRPC1 protein-dependent pathway regulates osteoclast formation and function. | Q37311840 | ||
| Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides | Q37344099 | ||
| Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis. | Q37376405 | ||
| Capacitative calcium entry revisited | Q37573268 | ||
| Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1). | Q37622523 | ||
| Transient receptor potential channelopathies | Q37686351 | ||
| Evolutionary origins of STIM1 and STIM2 within ancient Ca2+ signaling systems | Q37834772 | ||
| The closing and opening of TRPC channels by Homer1 and STIM1. | Q37868765 | ||
| Balancing calcium signals through TRPC5 and TRPC6 in podocytes | Q37943290 | ||
| The neglected CRAC proteins: Orai2, Orai3, and STIM2. | Q38124447 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 87-109 | |
| P577 | publication date | 2016-01-01 | |
| P1433 | published in | Advances in Experimental Medicine and Biology | Q4686385 |
| P1476 | title | Role of TRPC Channels in Store-Operated Calcium Entry | |
| P478 | volume | 898 |
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