Piceatannol Enhances the Antitumor Efficacy of Gemcitabine in Human A549 Non-Small Cell Lung Cancer Cells

scientific article published on January 2015

Piceatannol Enhances the Antitumor Efficacy of Gemcitabine in Human A549 Non-Small Cell Lung Cancer Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3727/096504015X14386062091398
P698PubMed publication ID26351210

P7228access restriction statusopen accessQ232932
P2093author name stringBin Xu
Ze-Zhang Tao
P2860cites workSignal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer linesQ24799458
Cancer statistics, 2010Q27860525
Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblastsQ33183062
Retrospective analysis of adverse drug reactions induced by gemcitabine treatment in patients with non-small cell lung cancerQ33358573
The phytochemical piceatannol induces the loss of CBL and CBL-associated proteinsQ33414474
Inhibition of lipopolysaccharide-induced interferon regulatory factor 3 activation and protection from septic shock by hydroxystilbenesQ34130251
Piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene) is a naturally occurring protein-tyrosine kinase inhibitorQ34473126
A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacyQ34618606
Synergistic induction of apoptosis in A549 cells by dihydroartemisinin and gemcitabineQ35066769
Treatment of advanced non small cell lung cancerQ35667817
Role of Bcl-2 family proteins and caspases in the regulation of apoptosis.Q37826384
The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update.Q38331196
Redox regulation in radiation-induced cytochrome c release from mitochondria of human lung carcinoma A549 cells.Q39899748
Anti-allergic activity of stilbenes from Korean rhubarb (Rheum undulatum L.): structure requirements for inhibition of antigen-induced degranulation and their effects on the release of TNF-alpha and IL-4 in RBL-2H3 cellsQ40521310
Piceatannol inhibits TNF-induced NF-kappaB activation and NF-kappaB-mediated gene expression through suppression of IkappaBalpha kinase and p65 phosphorylationQ40688390
Synergistic interaction between sorafenib and gemcitabine in EGFR-TKI-sensitive and EGFR-TKI-resistant human lung cancer cell linesQ41969486
Inhibition sites in F1-ATPase from bovine heart mitochondria.Q42134189
Catechol and hydroquinone have different redox properties responsible for their differential DNA-damaging abilityQ43860243
Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases.Q44039908
National survey of the medical treatment status for non-small cell lung cancer (NSCLC) in ChinaQ44515440
Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocytes: implications for anticancer propertiesQ46512344
Inhibitors of tyrosine kinase signaling cascade attenuated antigen challenge of guinea-pig airways in vitroQ46644298
Piceatannol, a stilbene phytochemical, inhibits mitochondrial F0F1-ATPase activity by targeting the F1 complexQ48150718
Inhibition of eukaryote serine/threonine-specific protein kinases by piceatannolQ48473039
Antioxidant activity of resveratrol, piceatannol and 3,3',4,4',5,5'-hexahydroxy-trans-stilbene in three leukemia cell lines.Q53343691
Isolation, Identification, and Antioxidant Activity of Three Stilbene Glucosides Newly Extracted fromVitis viniferaCell CulturesQ58985637
Synthesis and protein-tyrosine kinase inhibitory activity of polyhydroxylated stilbene analogues of piceatannolQ70507745
Use of potato disc and brine shrimp bioassays to detect activity and isolate piceatannol as the antileukemic principle from the seeds of Euphorbia lagascaeQ71396639
Genetic and pharmacological analyses of Syk function in alphaIIbbeta3 signaling in plateletsQ77293881
P433issue4
P921main subjectPicea glaucaQ128116
Picea abiesQ145992
Abies albaQ146992
Picea sitchensisQ147426
Picea engelmanniiQ165387
Picea marianaQ218425
Picea rubensQ469151
Picea obovataQ1137607
Picea glehniiQ1151932
piceatannolQ7190608
4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diolQ27164196
Picea jezoensis jezoensisQ104415627
P6954online access statusopen accessQ232932
P304page(s)213-217
P577publication date2015-01-01
P1433published inOncology ResearchQ15750114
P1476titlePiceatannol Enhances the Antitumor Efficacy of Gemcitabine in Human A549 Non-Small Cell Lung Cancer Cells
P478volume22

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cites work (P2860)
Q90119514Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway
Q114873387Arginase: An emerging and promising therapeutic target for cancer treatment
Q96345484Combination treatment of gemcitabine and sorafenib exerts a synergistic inhibitory effect on non-small cell lung cancer in vitro and in vivo via the epithelial-to-mesenchymal transition process
Q91397470Light-Cross-linked Enediyne Small-Molecule Micelle-Based Drug-Delivery System
Q59195878Oligostilbenoids in Vitis vinifera L. Pinot Noir grape cane extract: Isolation, characterization, in vitro antioxidant capacity and anti-proliferative effect on cancer cells
Q42690681Piceatannol induced apoptosis through up-regulation of microRNA-181a in melanoma cells
Q90514071Piceatannol pretreatment alleviates acute cardiac injury via regulating PI3K-Akt-eNOS signaling in H9c2 cells
Q92570719Piceatannol: A natural stilbene for the prevention and treatment of cancer
Q102206168Poly(anhydride-ester) gemcitabine: Synthesis and particle engineering of a high payload hydrolysable polymeric drug for cancer therapy
Q38721221Resveratrol and capsaicin used together as food complements reduce tumor growth and rescue full efficiency of low dose gemcitabine in a pancreatic cancer model
Q38965212Therapeutic Potential and Molecular Targets of Piceatannol in Chronic Diseases
Q47147122Trichosanthin enhances the antitumor effect of gemcitabine in non-small cell lung cancer via inhibition of the PI3K/AKT pathway